Understanding the drug exposure–response relationship of bedaquiline to predict efficacy for novel dosing regimens in the treatment of multidrug‐resistant tuberculosis

por Tanneau, Lénaïg, Karlsson, Mats O., Svensson, Elin M.
Publicado 2020

Exposure–safety analysis of QTc interval and transaminase levels following bedaquiline administration in patients with drug‐resistant tuberculosis

por Tanneau, Lénaïg, Svensson, Elin M., Rossenu, Stefaan, Karlsson, Mats O.
Publicado 2021

Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avel...

por Grisic, Ana-Marija, Xiong, Wenyuan, Tanneau, Lénaïg, Jönsson, Siv, Friberg, Lena E., Karlsson, Mats O., Dai, Haiqing, Zheng, Jenny, Girard, Pascal, Khandelwal, Akash
Publicado 2022

Population Pharmacokinetics of Delamanid and its Main Metabolite DM-6705 in Drug-Resistant Tuberculosis Patients Receiving Delamanid Alone or Coadministered with Bedaquiline

por Tanneau, Lénaïg, Karlsson, Mats O., Diacon, Andreas H., Shenje, Justin, De Los Rios, Jorge, Wiesner, Lubbe, Upton, Caryn M., Dooley, Kelly E., Maartens, Gary, Svensson, Elin M.
Publicado 2022

Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens

por Tanneau, Lénaïg, Karlsson, Mats O., Rosenkranz, Susan L., Cramer, Yoninah S., Shenje, Justin, Upton, Caryn M., Morganroth, Joel, Diacon, Andreas H., Maartens, Gary, Dooley, Kelly E., Svensson, Elin M.
Publicado 2022

Model-Predicted Impact of ECG Monitoring Strategies During Bedaquiline Treatment

por van Beek, Stijn W, Tanneau, Lénaïg, Meintjes, Graeme, Wasserman, Sean, Gandhi, Neel R, Campbell, Angie, Viljoen, Charle A, Wiesner, Lubbe, Aarnoutse, Rob E, Maartens, Gary, Brust, James C M, Svensson, Elin M
Publicado 2022