An in vitro ADME and in vivo Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives

por Tanner, Lloyd, Haynes, Richard K., Wiesner, Lubbe
Publicado 2019

Accumulation of TB-Active Compounds in Murine Organs Relevant to Infection by Mycobacterium tuberculosis

por Tanner, Lloyd, Haynes, Richard K., Wiesner, Lubbe
Publicado 2020

Experimental Model of Pulmonary Inflammation Induced by SARS-CoV-2 Spike Protein and Endotoxin

por Puthia, Manoj, Tanner, Lloyd, Petruk, Ganna, Schmidtchen, Artur
Publicado 2022

Zoledronic Acid Targeting of the Mevalonate Pathway Causes Reduced Cell Recruitment and Attenuates Pulmonary Fibrosis

por Tanner, Lloyd, Bergwik, Jesper, Single, Andrew B., Bhongir, Ravi K. V., Erjefält, Jonas S., Egesten, Arne
Publicado 2022

Substrate-specific binding of 8-oxoguanine DNA glycosylase 1 (OGG1) reprograms mucosal adaptations to chronic airway injury

por Pan, Lang, Vlahopoulos, Spiros, Tanner, Lloyd, Bergwik, Jesper, Bacsi, Attila, Radak, Zsolt, Egesten, Arne, Ba, Xueqing, Brasier, Allan R., Boldogh, Istvan
Publicado 2023

Intracellular Accumulation of Novel and Clinically Used TB Drugs Potentiates Intracellular Synergy

por Tanner, Lloyd, Mashabela, Gabriel T., Omollo, Charles C., de Wet, Timothy J., Parkinson, Christopher J., Warner, Digby F., Haynes, Richard K., Wiesner, Lubbe
Publicado 2021

Epigenetic control of type III interferon expression by 8-oxoguanine and its reader 8-oxoguanine DNA glycosylase1

por Xue, Yaoyao, Pan, Lang, Vlahopoulos, Spiros, Wang, Ke, Zheng, Xu, Radak, Zsolt, Bacsi, Attila, Tanner, Lloyd, Brasier, Allan R., Ba, Xueqing, Boldogh, Istvan
Publicado 2023

Pharmacological OGG1 inhibition decreases murine allergic airway inflammation

por Tanner, Lloyd, Bergwik, Jesper, Bhongir, Ravi K. V., Pan, Lang, Dong, Caijuan, Wallner, Olov, Kalderén, Christina, Helleday, Thomas, Boldogh, Istvan, Adner, Mikael, Egesten, Arne
Publicado 2022

Tartrate resistant acid phosphatase 5 (TRAP5) mediates immune cell recruitment in a murine model of pulmonary bacterial infection

por Tanner, Lloyd, Bergwik, Jesper, Bhongir, Ravi K. V., Puthia, Manoj, Lång, Pernilla, Ali, Mohamad N., Welinder, Charlotte, Önnerfjord, Patrik, Erjefält, Jonas S., Palmberg, Lena, Andersson, Göran, Egesten, Arne
Publicado 2022

Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions

por Zheng, Xu, Wang, Ke, Pan, Lang, Hao, Wenjing, Xue, Yaoyao, Bacsi, Attila, Vlahopoulos, Spiros A., Radak, Zsolt, Hazra, Tapas K., Brasier, Allan R., Tanner, Lloyd, Ba, Xueqing, Boldogh, Istvan
Publicado 2022

8-Oxoguanine targeted by 8-oxoguanine DNA glycosylase 1 (OGG1) is central to fibrogenic gene activation upon lung injury

por Pan, Lang, Hao, Wenjing, Xue, Yaoyao, Wang, Ke, Zheng, Xu, Luo, Jixian, Ba, Xueqing, Xiang, Yang, Qin, Xiaoqun, Bergwik, Jesper, Tanner, Lloyd, Egesten, Arne, Brasier, Allan R, Boldogh, Istvan
Publicado 2023

Lerisetron Analogues with Antimalarial Properties: Synthesis, Structure–Activity Relationship Studies, and Biological Assessment

por Mueller, Rudolf, Reddy, Virsinha, Nchinda, Aloysius T., Mebrahtu, Fanuel, Taylor, Dale, Lawrence, Nina, Tanner, Lloyd, Barnabe, Marine, Eyermann, Charles J., Zou, Bin, Kondreddi, Ravinder R., Lakshminarayana, Suresh B., Rottmann, Matthias, Street, Leslie J., Chibale, Kelly
Publicado 2020