Involvement of insulin receptor substrates in cognitive impairment and Alzheimer’s disease

por Tanokashira, Daisuke, Fukuokaya, Wataru, Taguchi, Akiko
Publicado 2019

Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons

por Mamada, Naomi, Tanokashira, Daisuke, Hosaka, Ai, Kametani, Fuyuki, Tamaoka, Akira, Araki, Wataru
Publicado 2015

The neurotoxicity of amyloid β-protein oligomers is reversible in a primary neuron model

por Tanokashira, Daisuke, Mamada, Naomi, Yamamoto, Fumiko, Taniguchi, Kaori, Tamaoka, Akira, Lakshmana, Madepalli K., Araki, Wataru
Publicado 2017

Metformin treatment ameliorates diabetes‐associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1

por Tanokashira, Daisuke, Kurata, Eiko, Fukuokaya, Wataru, Kawabe, Kenshiro, Kashiwada, Mana, Takeuchi, Hideyuki, Nakazato, Masamitsu, Taguchi, Akiko
Publicado 2018

Serine Phosphorylation of IRS1 Correlates with Aβ-Unrelated Memory Deficits and Elevation in Aβ Level Prior to the Onset of Memory Decline in AD

por Wang, Wei, Tanokashira, Daisuke, Fukui, Yusuke, Maruyama, Megumi, Kuroiwa, Chiemi, Saito, Takashi, Saido, Takaomi C., Taguchi, Akiko
Publicado 2019

LRP1 Downregulates the Alzheimer’s β-Secretase BACE1 by Modulating Its Intraneuronal Trafficking1,2,3

por Tanokashira, Daisuke, Motoki, Kazumi, Minegishi, Seiji, Hosaka, Ai, Mamada, Naomi, Tamaoka, Akira, Okada, Takashi, Lakshmana, Madepalli K., Araki, Wataru
Publicado 2015

Effects of high‐fat diet on nutrient metabolism and cognitive functions in young APPKI(NL‐G‐F/NL‐G‐F) mice

por Wang, Wei, Tanokashira, Daisuke, Shibayama, Yudai, Tsuji, Ryuhei, Maruyama, Megumi, Kuroiwa, Chiemi, Saito, Takashi, Saido, Takaomi C., Taguchi, Akiko
Publicado 2022