Discovery of a novel IL-15 based protein with improved developability and efficacy for cancer immunotherapy

por Hu, Qiyue, Ye, Xin, Qu, Xiangdong, Cui, Dongbing, Zhang, Lei, Xu, Zhibin, Wan, Hong, Zhang, Lianshan, Tao, Weikang
Publicado 2018

Visualization of Mitotic Arrest of Cell Cycle with Bioluminescence Imaging in Living Animals

por Zhang, Guo-Jun, Chen, Tsing-Bau, Davide, Joseph, Tao, Weikang, Vanko, Amy, Connolly, Brett, Williams, David L., Sur, Cyrille
Publicado 2013

Discovery of SHR9352: A Highly Potent G Protein-Biased μ-Opioid Receptor Agonist

por Li, Xin, He, Wei, Chen, Yang, Yang, Guimei, Wan, Hong, Zhang, Lei, Hu, Qiyue, Feng, Jun, Zhang, Zhigao, He, Feng, Bai, Chang, Zhang, Lianshan, You, Li, Tao, Weikang
Publicado 2017

In vivo acquired sorafenib-resistant patient-derived tumor model displays alternative angiogenic pathways, multi-drug resistance and chromosome instability

por Hu, Gang, Zhang, Yixin, Ouyang, Kedong, Xie, Fubo, Fang, Houshun, Yang, Xueyang, Liu, Kunyan, Wang, Zongyu, Tang, Xuzhen, Liu, Jibin, Yang, Lei, Jiang, Zhenzhou, Tao, Weikang, Zhou, He, Zhang, Luyong
Publicado 2018

Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis

por Liu, Suxing, Liu, Dong, Shen, Ru, Li, Di, Hu, Qiyue, Yan, Yinfa, Sun, Jiakang, Zhang, Fengqi, Wan, Hong, Dong, Ping, Feng, Jun, Zhang, Rumin, Li, Jing, Zhang, Lianshan, Tao, Weikang
Publicado 2021

A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer

por Liu, Suxing, Li, Di, Liu, Jian, Wang, Huiyun, Horecny, Ivana, Shen, Ru, Zhang, Rumin, Wu, Heping, Hu, Qiyue, Zhao, Peng, Zhang, Fengqi, Yan, Yinfa, Feng, Jun, Zhuang, Linghang, Li, Jing, Zhang, Lianshan, Tao, Weikang
Publicado 2021

SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis

por Song, Chunying, Liu, Dong, Liu, Suxing, Li, Di, Horecny, Ivana, Zhang, Xinzhu, Li, Puhui, Chen, Lei, Miller, Matthew, Chowdhury, Rasheduzzaman, Issa, Mena, Shen, Ru, Yan, Yinfa, Zhang, Fengqi, Zhang, Lei, Zhang, Limin, Bai, Chang, Feng, Jun, Zhuang, Linghang, Zhang, Rumin, Li, Jing, Wilkinson, Hilary, Liu, Jian, Tao, Weikang
Publicado 2022

Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways

por Zhou, Yu, Li, Xin, Shen, Ru, Wang, Xiangzhu, Zhang, Fan, Liu, Suxing, Li, Di, Liu, Jian, Li, Puhui, Yan, Yinfa, Dong, Ping, Zhang, Zhigao, Wu, Heping, Zhuang, Linghang, Chowdhury, Rasheduzzaman, Miller, Matthew, Issa, Mena, Mao, Yuchang, Chen, Hongli, Feng, Jun, Li, Jing, Bai, Chang, He, Feng, Tao, Weikang
Publicado 2022