A High Affinity hRpn2-Derived Peptide That Displaces Human Rpn13 from Proteasome in 293T Cells

por Lu, Xiuxiu, Liu, Fen, Durham, Sarah E., Tarasov, Sergey G., Walters, Kylie J.
Publicado 2015

Human γS-Crystallin Mutation F10_Y11delinsLN in the First Greek Key Pair Destabilizes and Impairs Tight Packing Causing Cortical Lamellar Cataract

por Vendra, Venkata Pulla Rao, Ostrowski, Christian, Dyba, Marzena A., Tarasov, Sergey G., Hejtmancik, J. Fielding
Publicado 2023

Virtual screening of ultra-large chemical libraries identifies cell-permeable small-molecule inhibitors of a “non-druggable” target, STAT3 N-terminal domain

por Bonilla, Pedro Andrade, Hoop, Cody L., Stefanisko, Karen, Tarasov, Sergey G., Sinha, Sourav, Nicklaus, Marc C., Tarasova, Nadya I.
Publicado 2023

Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination

por Stagno, Jason R., Altieri, Amanda S., Bubunenko, Mikhail, Tarasov, Sergey G., Li, Jess, Court, Donald L., Byrd, R. Andrew, Ji, Xinhua
Publicado 2011

High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site

por Chavan, Tanmay S., Jang, Hyunbum, Khavrutskii, Lyuba, Abraham, Sherwin J., Banerjee, Avik, Freed, Benjamin C., Johannessen, Liv, Tarasov, Sergey G., Gaponenko, Vadim, Nussinov, Ruth, Tarasova, Nadya I.
Publicado 2015

Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1

por Tripathi, Brajendra K., Grant, Tiera, Qian, Xiaolan, Zhou, Ming, Mertins, Philipp, Wang, Dunrui, Papageorge, Alex G., Tarasov, Sergey G., Hunter, Kent W., Carr, Steven A., Lowy, Douglas R.
Publicado 2017

Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10

por Buel, Gwen R., Chen, Xiang, Chari, Raj, O’Neill, Maura J., Ebelle, Danielle L., Jenkins, Conor, Sridharan, Vinidhra, Tarasov, Sergey G., Tarasova, Nadya I., Andresson, Thorkell, Walters, Kylie J.
Publicado 2020

Mechanisms of Unphosphorylated STAT3 Transcription Factor Binding to DNA

por Timofeeva, Olga A., Chasovskikh, Sergey, Lonskaya, Irina, Tarasova, Nadya I., Khavrutskii, Lyuba, Tarasov, Sergey G., Zhang, Xueping, Korostyshevskiy, Valeriy R., Cheema, Amrita, Zhang, Lihua, Dakshanamurthy, Sivanesan, Brown, Milton L., Dritschilo, Anatoly
Publicado 2012

Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets

por Lu, Xiuxiu, Nowicka, Urszula, Sridharan, Vinidhra, Liu, Fen, Randles, Leah, Hymel, David, Dyba, Marzena, Tarasov, Sergey G., Tarasova, Nadya I., Zhao, Xue Zhi, Hamazaki, Jun, Murata, Shigeo, Burke, Jr., Terrence R., Walters, Kylie J.
Publicado 2017

A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation

por Smith, Christopher E., Tsai, Yien Che, Liang, Yu-He, Khago, Domarin, Mariano, Jennifer, Li, Jess, Tarasov, Sergey G., Gergel, Emma, Tsai, Borong, Villaneuva, Matthew, Clapp, Michelle E., Magidson, Valentin, Chari, Raj, Byrd, R. Andrew, Ji, Xinhua, Weissman, Allan M.
Publicado 2021

Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma

por Lu, Xiuxiu, Sabbasani, Venkata R., Osei-Amponsa, Vasty, Evans, Christine N., King, Julianna C., Tarasov, Sergey G., Dyba, Marzena, Das, Sudipto, Chan, King C., Schwieters, Charles D., Choudhari, Sulbha, Fromont, Caroline, Zhao, Yongmei, Tran, Bao, Chen, Xiang, Matsuo, Hiroshi, Andresson, Thorkell, Chari, Raj, Swenson, Rolf E., Tarasova, Nadya I., Walters, Kylie J.
Publicado 2021