Complexity in genetic cardiomyopathies and new approaches for mechanism-based precision medicine

por Greenberg, Michael J., Tardiff, Jil C.
Publicado 2021

Basic Cardiovascular Sciences Scientific Sessions 2020: Emerging Opportunities in Cardiovascular Diseases

por Sadayappan, Sakthivel, Tardiff, Jil C., Wold, Loren E.
Publicado 2020

Myosin modulators: emerging approaches for the treatment of cardiomyopathies and heart failure

por Day, Sharlene M., Tardiff, Jil C., Ostap, E. Michael
Publicado 2022

Computational and biophysical determination of pathogenicity of variants of unknown significance in cardiac thin filament

por Mason, Allison B., Lynn, Melissa L., Baldo, Anthony P., Deranek, Andrea E., Tardiff, Jil C., Schwartz, Steven D.
Publicado 2021

Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Ca...

por Szatkowski, Lukasz, Lynn, Melissa L., Holeman, Teryn, Williams, Michael R., Baldo, Anthony P., Tardiff, Jil C., Schwartz, Steven D.
Publicado 2019

Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation

por Hill, Meghan G., Sekhon, Mehtab K., Reed, Kathryn L., Anderson, Caroline F., Borjon, Nydia D., Tardiff, Jil C., Barber, Brent J.
Publicado 2015

Sex‐Related Differences in Genetic Cardiomyopathies

por Argirò, Alessia, Ho, Carolyn, Day, Sharlene M., van der Velden, Jolanda, Cerbai, Elisabetta, Saberi, Sara, Tardiff, Jil C., Lakdawala, Neal K., Olivotto, Iacopo
Publicado 2022

Thin filament cardiomyopathies: A review of genetics, disease mechanisms, and emerging therapeutics

por Keyt, Lucas K., Duran, Jason M., Bui, Quan M., Chen, Chao, Miyamoto, Michael I., Silva Enciso, Jorge, Tardiff, Jil C., Adler, Eric D.
Publicado 2022

In Vivo Cannulation Methods for Cardiomyocytes Isolation from Heart Disease Models

por Jian, Zhong, Chen, Yi-Je, Shimkunas, Rafael, Jian, Yuwen, Jaradeh, Mark, Chavez, Karen, Chiamvimonvat, Nipavan, Tardiff, Jil C., Izu, Leighton T., Ross, Robert S., Chen-Izu, Ye
Publicado 2016

Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies

por Lehman, Sarah J., Meller, Artur, Solieva, Shahlo O., Lotthammer, Jeffrey M., Greenberg, Lina, Langer, Stephen J., Greenberg, Michael J., Tardiff, Jil C., Bowman, Gregory R., Leinwand, Leslie
Publicado 2023

Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response

por Chowdhury, Shamim A. K., Warren, Chad M., Simon, Jillian N., Ryba, David M., Batra, Ashley, Varga, Peter, Kranias, Evangelia G., Tardiff, Jil C., Solaro, R. John, Wolska, Beata M.
Publicado 2020

Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts

por Powers, Joseph D., Kooiker, Kristina B., Mason, Allison B., Teitgen, Abigail E., Flint, Galina V., Tardiff, Jil C., Schwartz, Steven D., McCulloch, Andrew D., Regnier, Michael, Davis, Jennifer, Moussavi-Harami, Farid
Publicado 2020

Differences in microRNA-29 and Pro-fibrotic Gene Expression in Mouse and Human Hypertrophic Cardiomyopathy

por Liu, Yamin, Afzal, Junaid, Vakrou, Styliani, Greenland, Gabriela V., Talbot, C. Conover, Hebl, Virginia B., Guan, Yufan, Karmali, Rehan, Tardiff, Jil C., Leinwand, Leslie A., Olgin, Jeffrey E., Das, Samarjit, Fukunaga, Ryuya, Abraham, M. Roselle
Publicado 2019