Neuroblastoma and the epigenome

por Fetahu, Irfete S., Taschner-Mandl, Sabine
Publicado 2021

Mathematical Model of Clonal Evolution Proposes a Personalised Multi-Modal Therapy for High-Risk Neuroblastoma

por Italia, Matteo, Wertheim, Kenneth Y., Taschner-Mandl, Sabine, Walker, Dawn, Dercole, Fabio
Publicado 2023

Enriched Bone Marrow Derived Disseminated Neuroblastoma Cells Can Be a Reliable Source for Gene Expression Studies—A Validation Study

por Rifatbegovic, Fikret, Abbasi, M. Reza, Taschner-Mandl, Sabine, Kauer, Maximilian, Weinhäusel, Andreas, Handgretinger, Rupert, Ambros, Peter F.
Publicado 2015

A Preclinical Embryonic Zebrafish Xenograft Model to Investigate CAR T Cells in Vivo

por Pascoal, Susana, Salzer, Benjamin, Scheuringer, Eva, Wenninger-Weinzierl, Andrea, Sturtzel, Caterina, Holter, Wolfgang, Taschner-Mandl, Sabine, Lehner, Manfred, Distel, Martin
Publicado 2020

Comparison of three different methods to detect bone marrow involvement in patients with neuroblastoma

por Schriegel, Felix, Taschner-Mandl, Sabine, Bernkopf, Marie, Grunwald, Uwe, Siebert, Nikolai, Ambros, Peter F., Ambros, Inge, Lode, Holger N., Henze, Guenter, Ehlert, Karoline
Publicado 2021

Neuroblastoma cells undergo transcriptomic alterations upon dissemination into the bone marrow and subsequent tumor progression

por Rifatbegovic, Fikret, Frech, Christian, Abbasi, M. Reza, Taschner‐Mandl, Sabine, Weiss, Tamara, Schmidt, Wolfgang M., Schmidt, Iris, Ladenstein, Ruth, Ambros, Inge M., Ambros, Peter F.
Publicado 2017

Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide

por Byrgazov, Konstantin, Anderson, Claes, Salzer, Benjamin, Bozsaky, Eva, Larsson, Rolf, Gullbo, Joachim, Lehner, Manfred, Lehmann, Fredrik, Slipicevic, Ana, Kager, Leo, Fryknäs, Mårten, Taschner-Mandl, Sabine
Publicado 2020

Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence

por Taschner-Mandl, Sabine, Schwarz, Magdalena, Blaha, Johanna, Kauer, Maximilian, Kromp, Florian, Frank, Nelli, Rifatbegovic, Fikret, Weiss, Tamara, Ladenstein, Ruth, Hohenegger, Martin, Ambros, Inge M., Ambros, Peter F.
Publicado 2015

Human repair‐related Schwann cells adopt functions of antigen‐presenting cells in vitro

por Berner, Jakob, Weiss, Tamara, Sorger, Helena, Rifatbegovic, Fikret, Kauer, Max, Windhager, Reinhard, Dohnal, Alexander, Ambros, Peter F., Ambros, Inge M., Boztug, Kaan, Steinberger, Peter, Taschner‐Mandl, Sabine
Publicado 2022

Mutational spectrum of ATRX aberrations in neuroblastoma and associated patient and tumor characteristics

por van Gerven, Michael R., Bozsaky, Eva, Matser, Yvette A. H., Vosseberg, Julian, Taschner‐Mandl, Sabine, Koster, Jan, Tytgat, Godelieve A. M., Molenaar, Jan J., van den Boogaard, Marlinde
Publicado 2022

Schwann cell plasticity regulates neuroblastic tumor cell differentiation via epidermal growth factor-like protein 8

por Weiss, Tamara, Taschner-Mandl, Sabine, Janker, Lukas, Bileck, Andrea, Rifatbegovic, Fikret, Kromp, Florian, Sorger, Helena, Kauer, Maximilian O., Frech, Christian, Windhager, Reinhard, Gerner, Christopher, Ambros, Peter F., Ambros, Inge M.
Publicado 2021

VP2: Schwann Cells Regulate Neuronal Differentiation by Epidermal Growth Factor-Like Protein 8

por Weiss, Tamara, Taschner-Mandl, Sabine, Janker, Lukas, Bileck, Andrea, Rifatbegovic, Fikret, Kromp, Florian, Sorger, Helena, Kauer, Maximilian O., Frech, Christian, Windhager, Reinhard, Gerner, Christopher, Ambros, Peter F., Ambros, Inge M.
Publicado 2022

An annotated fluorescence image dataset for training nuclear segmentation methods

por Kromp, Florian, Bozsaky, Eva, Rifatbegovic, Fikret, Fischer, Lukas, Ambros, Magdalena, Berneder, Maria, Weiss, Tamara, Lazic, Daria, Dörr, Wolfgang, Hanbury, Allan, Beiske, Klaus, Ambros, Peter F., Ambros, Inge M., Taschner-Mandl, Sabine
Publicado 2020

Landscape of Bone Marrow Metastasis in Human Neuroblastoma Unraveled by Transcriptomics and Deep Multiplex Imaging

por Lazic, Daria, Kromp, Florian, Rifatbegovic, Fikret, Repiscak, Peter, Kirr, Michael, Mivalt, Filip, Halbritter, Florian, Bernkopf, Marie, Bileck, Andrea, Ussowicz, Marek, Ambros, Inge M., Ambros, Peter F., Gerner, Christopher, Ladenstein, Ruth, Ostalecki, Christian, Taschner-Mandl, Sabine
Publicado 2021

Comparative Multicentric Evaluation of Inter-Observer Variability in Manual and Automatic Segmentation of Neuroblastic Tumors in Magnetic Resonance Images

por Veiga-Canuto, Diana, Cerdà-Alberich, Leonor, Sangüesa Nebot, Cinta, Martínez de las Heras, Blanca, Pötschger, Ulrike, Gabelloni, Michela, Carot Sierra, José Miguel, Taschner-Mandl, Sabine, Düster, Vanessa, Cañete, Adela, Ladenstein, Ruth, Neri, Emanuele, Martí-Bonmatí, Luis
Publicado 2022

Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis

por Fetahu, Irfete S., Esser-Skala, Wolfgang, Dnyansagar, Rohit, Sindelar, Samuel, Rifatbegovic, Fikret, Bileck, Andrea, Skos, Lukas, Bozsaky, Eva, Lazic, Daria, Shaw, Lisa, Tötzl, Marcus, Tarlungeanu, Dora, Bernkopf, Marie, Rados, Magdalena, Weninger, Wolfgang, Tomazou, Eleni M., Bock, Christoph, Gerner, Christopher, Ladenstein, Ruth, Farlik, Matthias, Fortelny, Nikolaus, Taschner-Mandl, Sabine
Publicado 2023

Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroup

por Martinez-Monleon, Angela, Kryh Öberg, Hanna, Gaarder, Jennie, Berbegall, Ana P., Javanmardi, Niloufar, Djos, Anna, Ussowicz, Marek, Taschner-Mandl, Sabine, Ambros, Inge M., Øra, Ingrid, Sandstedt, Bengt, Beiske, Klaus, Ladenstein, Ruth, Noguera, Rosa, Ambros, Peter F., Gordon Murkes, Lena, Ljungman, Gustaf, Kogner, Per, Fransson, Susanne, Martinsson, Tommy
Publicado 2022

Independent Validation of a Deep Learning nnU-Net Tool for Neuroblastoma Detection and Segmentation in MR Images

por Veiga-Canuto, Diana, Cerdà-Alberich, Leonor, Jiménez-Pastor, Ana, Carot Sierra, José Miguel, Gomis-Maya, Armando, Sangüesa-Nebot, Cinta, Fernández-Patón, Matías, Martínez de las Heras, Blanca, Taschner-Mandl, Sabine, Düster, Vanessa, Pötschger, Ulrike, Simon, Thorsten, Neri, Emanuele, Alberich-Bayarri, Ángel, Cañete, Adela, Hero, Barbara, Ladenstein, Ruth, Martí-Bonmatí, Luis
Publicado 2023

Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts

por Sturtzel, C., Grissenberger, S., Bozatzi, P., Scheuringer, E., Wenninger-Weinzierl, A., Zajec, Z., Dernovšek, J., Pascoal, S., Gehl, V., Kutsch, A., Granig, A., Rifatbegovic, F., Carre, M., Lang, A., Valtingojer, I., Moll, J., Lötsch, D., Erhart, F., Widhalm, G., Surdez, D., Delattre, O., André, N., Stampfl, J., Tomašič, T., Taschner-Mandl, S., Distel, M.
Publicado 2023

The evolutionary dynamics of extrachromosomal DNA in human cancers

por Lange, Joshua T., Rose, John C., Chen, Celine Y., Pichugin, Yuriy, Xie, Liangqi, Tang, Jun, Hung, King L., Yost, Kathryn E., Shi, Quanming, Erb, Marcella L., Rajkumar, Utkrisht, Wu, Sihan, Taschner-Mandl, Sabine, Bernkopf, Marie, Swanton, Charles, Liu, Zhe, Huang, Weini, Chang, Howard Y., Bafna, Vineet, Henssen, Anton G., Werner, Benjamin, Mischel, Paul S.
Publicado 2022