Recent advances in lung organoid development and applications in disease modeling

por Vazquez-Armendariz, Ana I., Tata, Purushothama Rao
Publicado 2023

Defined conditions for long-term expansion of murine and human alveolar epithelial stem cells in three-dimensional cultures

por Konishi, Satoshi, Tata, Aleksandra, Tata, Purushothama Rao
Publicado 2022

IL-1 and TNFα Contribute to the Inflammatory Niche to Enhance Alveolar Regeneration

por Katsura, Hiroaki, Kobayashi, Yoshihiko, Tata, Purushothama Rao, Hogan, Brigid L.M.
Publicado 2019

An In Vitro Microfluidic Alveolus Model to Study Lung Biomechanics

por Kumar, Vardhman, Madhurakkat Perikamana, Sajeesh Kumar, Tata, Aleksandra, Hoque, Jiaul, Gilpin, Anna, Tata, Purushothama Rao, Varghese, Shyni
Publicado 2022

Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice

por Uezu, Akiyoshi, Hisey, Erin, Kobayashi, Yoshihiko, Gao, Yudong, Bradshaw, Tyler WA, Devlin, Patrick, Rodriguiz, Ramona, Tata, Purushothama Rao, Soderling, Scott
Publicado 2019

Parent stem cells can serve as niches for their own daughter cells

por Pardo-Saganta, Ana, Tata, Purushothama Rao, Law, Brandon M., Saez, Borja, Chow, Ryan Dz-Wei, Prabhu, Mythili, Gridley, Thomas, Rajagopal, Jayaraj
Publicado 2015

Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations

por Leinroth, Abigail P., Mirando, Anthony J., Rouse, Douglas, Kobayahsi, Yoshihiko, Tata, Purushothama Rao, Rueckert, Helen E., Liao, Yihan, Long, Jason T., Chakkalakal, Joe V., Hilton, Matthew J.
Publicado 2022

Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair

por Ide, Shintaro, Ide, Kana, Abe, Koki, Kobayashi, Yoshihiko, Kitai, Hiroki, McKey, Jennifer, Strausser, Sarah A., O’Brien, Lori L., Tata, Aleksandra, Tata, Purushothama Rao, Souma, Tomokazu
Publicado 2022

Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

por Ide, Shintaro, Kobayashi, Yoshihiko, Ide, Kana, Strausser, Sarah A, Abe, Koki, Herbek, Savannah, O'Brien, Lori L, Crowley, Steven D, Barisoni, Laura, Tata, Aleksandra, Tata, Purushothama Rao, Souma, Tomokazu
Publicado 2021

Dedifferentiation of committed epithelial cells into stem cells in vivo

por Tata, Purushothama Rao, Mou, Hongmei, Pardo-Saganta, Ana, Zhao, Rui, Prabhu, Mythili, Prabhu, Mythili, Law, Brandon M., Vinarsky, Vladimir, Cho, Josalyn L., Breton, Sylvie, Sahay, Amar, Medoff, Benjamin D., Rajagopal, Jayaraj
Publicado 2013

Multi-apical polarity of alveolar stem cells and their dynamics during lung development and regeneration

por Konkimalla, Arvind, Konishi, Satoshi, Kobayashi, Yoshihiko, Kadur Lakshminarasimha Murthy, Preetish, Macadlo, Lauren, Mukherjee, Ananya, Elmore, Zachary, Kim, So-Jin, Pendergast, Ann Marie, Lee, Patty J., Asokan, Aravind, Knudsen, Lars, Bravo-Cordero, Jose Javier, Tata, Aleksandra, Tata, Purushothama Rao
Publicado 2022

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction

por Katsura, Hiroaki, Sontake, Vishwaraj, Tata, Aleksandra, Kobayashi, Yoshihiko, Edwards, Caitlin E., Heaton, Brook E., Konkimalla, Arvind, Asakura, Takanori, Mikami, Yu, Fritch, Ethan J., Lee, Patty J., Heaton, Nicholas S., Boucher, Richard C., Randell, Scott H., Baric, Ralph S., Tata, Purushothama Rao
Publicado 2020

Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration

por Moiseenko, Alena, Vazquez-Armendariz, Ana Ivonne, Kheirollahi, Vahid, Chu, Xuran, Tata, Aleksandra, Rivetti, Stefano, Günther, Stefan, Lebrigand, Kevin, Herold, Susanne, Braun, Thomas, Mari, Bernard, De Langhe, Stijn, Kwapiszewska, Grazyna, Günther, Andreas, Chen, Chengshui, Seeger, Werner, Tata, Purushothama Rao, Zhang, Jin-San, Bellusci, Saverio, El Agha, Elie
Publicado 2020

Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF‐PU.1‐DPP4 Axis

por Wang, Lihua, Wang, Ergang, Prado Balcazar, Jorge, Wu, Zhenzhen, Xiang, Kun, Wang, Yi, Huang, Qiang, Negrete, Marcos, Chen, Kai‐Yuan, Li, Wei, Fu, Yujie, Dohlman, Anders, Mines, Robert, Zhang, Liwen, Kobayashi, Yoshihiko, Chen, Tianyi, Shi, Guizhi, Shen, John Paul, Kopetz, Scott, Tata, Purushothama Rao, Moreno, Victor, Gersbach, Charles, Crawford, Gregory, Hsu, David, Huang, Emina, Bu, Pengcheng, Shen, Xiling
Publicado 2021

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

por Montoro, Daniel T., Haber, Adam L., Biton, Moshe, Vinarsky, Vladimir, Lin, Brian, Birket, Susan, Yuan, Feng, Chen, Sijia, Leung, Hui Min, Villoria, Jorge, Rogel, Noga, Burgin, Grace, Tsankov, Alexander, Waghray, Avinash, Slyper, Michal, Waldmann, Julia, Nguyen, Lan, Dionne, Danielle, Rozenblatt-Rosen, Orit, Tata, Purushothama Rao, Mou, Hongmei, Shivaraju, Manjunatha, Bihler, Hermann, Mense, Martin, Tearney, Guillermo J., Rowe, Steven M., Engelhardt, John F., Regev, Aviv, Rajagopal, Jayaraj
Publicado 2018

A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics

por Sapoznik, Etai, Chang, Bo-Jui, Huh, Jaewon, Ju, Robert J, Azarova, Evgenia V, Pohlkamp, Theresa, Welf, Erik S, Broadbent, David, Carisey, Alexandre F, Stehbens, Samantha J, Lee, Kyung-Min, Marín, Arnaldo, Hanker, Ariella B, Schmidt, Jens C, Arteaga, Carlos L, Yang, Bin, Kobayashi, Yoshihiko, Tata, Purushothama Rao, Kruithoff, Rory, Doubrovinski, Konstantin, Shepherd, Douglas P, Millett-Sikking, Alfred, York, Andrew G, Dean, Kevin M, Fiolka, Reto P
Publicado 2020

Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication

por Yaron, Tomer M., Heaton, Brook E., Levy, Tyler M., Johnson, Jared L., Jordan, Tristan X., Cohen, Benjamin M., Kerelsky, Alexander, Lin, Ting-Yu, Liberatore, Katarina M., Bulaon, Danielle K., Van Nest, Samantha J., Koundouros, Nikos, Kastenhuber, Edward R., Mercadante, Marisa N., Shobana-Ganesh, Kripa, He, Long, Schwartz, Robert E., Chen, Shuibing, Weinstein, Harel, Elemento, Olivier, Piskounova, Elena, Nilsson-Payant, Benjamin E., Lee, Gina, Trimarco, Joseph D., Burke, Kaitlyn N., Hamele, Cait E., Chaparian, Ryan R., Harding, Alfred T., Tata, Aleksandra, Zhu, Xinyu, Tata, Purushothama Rao, Smith, Clare M., Possemato, Anthony P., Tkachev, Sasha L., Hornbeck, Peter V., Beausoleil, Sean A., Anand, Shankara K., Aguet, François, Getz, Gad, Davidson, Andrew D., Heesom, Kate, Kavanagh-Williamson, Maia, Matthews, David A., tenOever, Benjamin R., Cantley, Lewis C., Blenis, John, Heaton, Nicholas S.
Publicado 2022

An integrated cell atlas of the lung in health and disease

por Sikkema, Lisa, Ramírez-Suástegui, Ciro, Strobl, Daniel C., Gillett, Tessa E., Zappia, Luke, Madissoon, Elo, Markov, Nikolay S., Zaragosi, Laure-Emmanuelle, Ji, Yuge, Ansari, Meshal, Arguel, Marie-Jeanne, Apperloo, Leonie, Banchero, Martin, Bécavin, Christophe, Berg, Marijn, Chichelnitskiy, Evgeny, Chung, Mei-i, Collin, Antoine, Gay, Aurore C. A., Gote-Schniering, Janine, Hooshiar Kashani, Baharak, Inecik, Kemal, Jain, Manu, Kapellos, Theodore S., Kole, Tessa M., Leroy, Sylvie, Mayr, Christoph H., Oliver, Amanda J., von Papen, Michael, Peter, Lance, Taylor, Chase J., Walzthoeni, Thomas, Xu, Chuan, Bui, Linh T., De Donno, Carlo, Dony, Leander, Faiz, Alen, Guo, Minzhe, Gutierrez, Austin J., Heumos, Lukas, Huang, Ni, Ibarra, Ignacio L., Jackson, Nathan D., Kadur Lakshminarasimha Murthy, Preetish, Lotfollahi, Mohammad, Tabib, Tracy, Talavera-López, Carlos, Travaglini, Kyle J., Wilbrey-Clark, Anna, Worlock, Kaylee B., Yoshida, Masahiro, van den Berge, Maarten, Bossé, Yohan, Desai, Tushar J., Eickelberg, Oliver, Kaminski, Naftali, Krasnow, Mark A., Lafyatis, Robert, Nikolic, Marko Z., Powell, Joseph E., Rajagopal, Jayaraj, Rojas, Mauricio, Rozenblatt-Rosen, Orit, Seibold, Max A., Sheppard, Dean, Shepherd, Douglas P., Sin, Don D., Timens, Wim, Tsankov, Alexander M., Whitsett, Jeffrey, Xu, Yan, Banovich, Nicholas E., Barbry, Pascal, Duong, Thu Elizabeth, Falk, Christine S., Meyer, Kerstin B., Kropski, Jonathan A., Pe’er, Dana, Schiller, Herbert B., Tata, Purushothama Rao, Schultze, Joachim L., Teichmann, Sara A., Misharin, Alexander V., Nawijn, Martijn C., Luecken, Malte D., Theis, Fabian J.
Publicado 2023

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

por Delorey, Toni M., Ziegler, Carly G. K., Heimberg, Graham, Normand, Rachelly, Yang, Yiming, Segerstolpe, Asa, Abbondanza, Domenic, Fleming, Stephen J., Subramanian, Ayshwarya, Montoro, Daniel T., Jagadeesh, Karthik A., Dey, Kushal K., Sen, Pritha, Slyper, Michal, Pita-Juárez, Yered H., Phillips, Devan, Bloom-Ackerman, Zohar, Barkas, Nick, Ganna, Andrea, Gomez, James, Normandin, Erica, Naderi, Pourya, Popov, Yury V., Raju, Siddharth S., Niezen, Sebastian, Tsai, Linus T.-Y., Siddle, Katherine J., Sud, Malika, Tran, Victoria M., Vellarikkal, Shamsudheen K., Amir-Zilberstein, Liat, Atri, Deepak S., Beechem, Joseph, Brook, Olga R., Chen, Jonathan, Divakar, Prajan, Dorceus, Phylicia, Engreitz, Jesse M., Essene, Adam, Fitzgerald, Donna M., Fropf, Robin, Gazal, Steven, Gould, Joshua, Grzyb, John, Harvey, Tyler, Hecht, Jonathan, Hether, Tyler, Jane-Valbuena, Judit, Leney-Greene, Michael, Ma, Hui, McCabe, Cristin, McLoughlin, Daniel E., Miller, Eric M., Muus, Christoph, Niemi, Mari, Padera, Robert, Pan, Liuliu, Pant, Deepti, Pe’er, Carmel, Pfiffner-Borges, Jenna, Pinto, Christopher J., Plaisted, Jacob, Reeves, Jason, Ross, Marty, Rudy, Melissa, Rueckert, Erroll H., Siciliano, Michelle, Sturm, Alexander, Todres, Ellen, Waghray, Avinash, Warren, Sarah, Zhang, Shuting, Zollinger, Daniel R., Cosimi, Lisa, Gupta, Rajat M., Hacohen, Nir, Hide, Winston, Price, Alkes L., Rajagopal, Jayaraj, Tata, Purushothama Rao, Riedel, Stefan, Szabo, Gyongyi, Tickle, Timothy L., Hung, Deborah, Sabeti, Pardis C., Novak, Richard, Rogers, Robert, Ingber, Donald E., Jiang, Z. Gordon, Juric, Dejan, Babadi, Mehrtash, Farhi, Samouil L., Stone, James R., Vlachos, Ioannis S., Solomon, Isaac H., Ashenberg, Orr, Porter, Caroline B.M., Li, Bo, Shalek, Alex K., Villani, Alexandra-Chloé, Rozenblatt-Rosen, Orit, Regev, Aviv
Publicado 2021