Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro, and X-ray Crystallography

por Yoshino, Ryunosuke, Yasuo, Nobuaki, Hagiwara, Yohsuke, Ishida, Takashi, Inaoka, Daniel Ken, Amano, Yasushi, Tateishi, Yukihiro, Ohno, Kazuki, Namatame, Ichiji, Niimi, Tatsuya, Orita, Masaya, Kita, Kiyoshi, Akiyama, Yutaka, Sekijima, Masakazu
Publicado 2023

In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease

por Yoshino, Ryunosuke, Yasuo, Nobuaki, Hagiwara, Yohsuke, Ishida, Takashi, Inaoka, Daniel Ken, Amano, Yasushi, Tateishi, Yukihiro, Ohno, Kazuki, Namatame, Ichiji, Niimi, Tatsuya, Orita, Masaya, Kita, Kiyoshi, Akiyama, Yutaka, Sekijima, Masakazu
Publicado 2017