Deciphering and reprogramming the cyclization regioselectivity in bifurcation of indole alkaloid biosynthesis

por Wang, Zhuo, Xiao, Yiren, Wu, Song, Chen, Jianghua, Li, Ang, Tatsis, Evangelos C.
Publicado 2022

Unprecedented Utilization of Pelargonidin and Indole for the Biosynthesis of Plant Indole Alkaloids

por Warskulat, Anne‐Christin, Tatsis, Evangelos C., Dudek, Bettina, Kai, Marco, Lorenz, Sybille, Schneider, Bernd
Publicado 2016

Unlocking the Diversity of Alkaloids in Catharanthus roseus: Nuclear Localization Suggests Metabolic Channeling in Secondary Metabolism

por Stavrinides, Anna, Tatsis, Evangelos C., Foureau, Emilien, Caputi, Lorenzo, Kellner, Franziska, Courdavault, Vincent, O’Connor, Sarah E.
Publicado 2015

Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity

por Stavrinides, Anna, Tatsis, Evangelos C., Caputi, Lorenzo, Foureau, Emilien, Stevenson, Clare E. M., Lawson, David M., Courdavault, Vincent, O'Connor, Sarah E.
Publicado 2016

Discovery of a Short‐Chain Dehydrogenase from Catharanthus roseus that Produces a New Monoterpene Indole Alkaloid

por Stavrinides, Anna K., Tatsis, Evangelos C., Dang, Thu‐Thuy, Caputi, Lorenzo, Stevenson, Clare E. M., Lawson, David M., Schneider, Bernd, O'Connor, Sarah E.
Publicado 2018

A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate

por Tatsis, Evangelos C., Carqueijeiro, Inês, Dugé de Bernonville, Thomas, Franke, Jakob, Dang, Thu-Thuy T., Oudin, Audrey, Lanoue, Arnaud, Lafontaine, Florent, Stavrinides, Anna K., Clastre, Marc, Courdavault, Vincent, O’Connor, Sarah E.
Publicado 2017

An NPF Transporter Exports a Central Monoterpene Indole Alkaloid Intermediate from the Vacuole

por Payne, Richard M. E., Xu, Deyang, Foureau, Emilien, Teto Carqueijeiro, Marta Ines Soares, Oudin, Audrey, de Bernonville, Thomas Dugé, Novak, Vlastimil, Burow, Meike, Olsen, Carl-Erik, Jones, D. Marc, Tatsis, Evangelos C., Pendle, Ali, Halkier, Barbara Ann, Geu-Flores, Fernando, Courdavault, Vincent, Nour-Eldin, Hussam Hassan, O’Connor, Sarah E.
Publicado 2017