Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions

por Britz, Hannah, Hanke, Nina, Taub, Mitchell E., Wang, Ting, Prasad, Bhagwat, Fernandez, Éric, Stopfer, Peter, Nock, Valerie, Lehr, Thorsten
Publicado 2020

Effects of Metformin and Furosemide on Rosuvastatin Pharmacokinetics in Healthy Volunteers: Implications for Their Use as Probe Drugs in a Transporter Cocktail

por Stopfer, Peter, Giessmann, Thomas, Hohl, Kathrin, Sharma, Ashish, Ishiguro, Naoki, Taub, Mitchell E., Jungnik, Arvid, Gansser, Dietmar, Ebner, Thomas, Müller, Fabian
Publicado 2017

Optimization of a drug transporter probe cocktail: potential screening tool for transporter‐mediated drug–drug interactions

por Stopfer, Peter, Giessmann, Thomas, Hohl, Kathrin, Hutzel, Sabine, Schmidt, Sven, Gansser, Dietmar, Ishiguro, Naoki, Taub, Mitchell E., Sharma, Ashish, Ebner, Thomas, Müller, Fabian
Publicado 2018

Validation of a Drug Transporter Probe Cocktail Using the Prototypical Inhibitors Rifampin, Probenecid, Verapamil, and Cimetidine

por Wiebe, Sabrina T., Giessmann, Thomas, Hohl, Kathrin, Schmidt-Gerets, Sven, Hauel, Edith, Jambrecina, Alen, Bader, Kerstin, Ishiguro, Naoki, Taub, Mitchell E., Sharma, Ashish, Ebner, Thomas, Mikus, Gerd, Fromm, Martin F., Müller, Fabian, Stopfer, Peter
Publicado 2020