Using docking and alchemical free energy approach to determine the binding mechanism of eEF2K inhibitors and prioritizing the compound synthesis

por Wang, Qiantao, Edupuganti, Ramakrishna, Tavares, Clint D. J., Dalby, Kevin N., Ren, Pengyu
Publicado 2015

Targeted Silencing of Elongation Factor 2 Kinase Suppresses Growth and Sensitizes Tumors to Doxorubicin in an Orthotopic Model of Breast Cancer

por Tekedereli, Ibrahim, Alpay, S. Neslihan, Tavares, Clint D. J., Cobanoglu, Zehra E., Kaoud, Tamer S., Sahin, Ibrahim, Sood, Anil K., Lopez-Berestein, Gabriel, Dalby, Kevin N., Ozpolat, Bulent
Publicado 2012

Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo

por Kaoud, Tamer S., Johnson, William H., Ebelt, Nancy D., Piserchio, Andrea, Zamora-Olivares, Diana, Van Ravenstein, Sabrina X., Pridgen, Jacey R., Edupuganti, Ramakrishna, Sammons, Rachel, Cano, Micael, Warthaka, Mangalika, Harger, Matthew, Tavares, Clint D. J., Park, Jihyun, Radwan, Mohamed F., Ren, Pengyu, Anslyn, Eric V., Tsai, Kenneth Y., Ghose, Ranajeet, Dalby, Kevin N.
Publicado 2019