Identifying Cytochrome P450 Functional Networks and Their Allosteric Regulatory Elements

por Liu, Jin, Tawa, Gregory J., Wallqvist, Anders
Publicado 2013

Exploiting large-scale drug-protein interaction information for computational drug repurposing

por Liu, Ruifeng, Singh, Narender, Tawa, Gregory J, Wallqvist, Anders, Reifman, Jaques
Publicado 2014

A physicochemical descriptor-based scoring scheme for effective and rapid filtering of kinase-like chemical space

por Singh, Narender, Sun, Hongmao, Chaudhury, Sidhartha, AbdulHameed, Mohamed Diwan M, Wallqvist, Anders, Tawa, Gregory
Publicado 2012

Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species

por Tawa, Gregory J., Braisted, John, Gerhold, David, Grewal, Gurmit, Mazcko, Christina, Breen, Matthew, Sittampalam, Gurusingham, LeBlanc, Amy K.
Publicado 2021

Quatramer™ encapsulation of dual‐targeted PI3‐Kδ/HDAC6 inhibitor, HSB‐510, suppresses growth of breast cancer

por Tiwari, Sachchidanand, Liu, Suiyang, Anees, Mohd, Mehrotra, Neha, Thakur, Ashish, Tawa, Gregory J., Grewal, Gurmit, Stone, Richard, Kharbanda, Surender, Singh, Harpal
Publicado 2023

Systems Level Analysis and Identification of Pathways and Networks Associated with Liver Fibrosis

por AbdulHameed, Mohamed Diwan M., Tawa, Gregory J., Kumar, Kamal, Ippolito, Danielle L., Lewis, John A., Stallings, Jonathan D., Wallqvist, Anders
Publicado 2014

A systems biology strategy to identify molecular mechanisms of action and protein indicators of traumatic brain injury

por Yu, Chenggang, Boutté, Angela, Yu, Xueping, Dutta, Bhaskar, Feala, Jacob D, Schmid, Kara, Dave, Jitendra, Tawa, Gregory J, Wallqvist, Anders, Reifman, Jaques
Publicado 2015

Novel lead structures with both Plasmodium falciparum gametocytocidal and asexual blood stage activity identified from high throughput compound screening

por Sun, Wei, Huang, Xiuli, Li, Hao, Tawa, Gregory, Fisher, Ethan, Tanaka, Takeshi Q., Shinn, Paul, Huang, Wenwei, Williamson, Kim C., Zheng, Wei
Publicado 2017

Characterization of Chemically Induced Liver Injuries Using Gene Co-Expression Modules

por Tawa, Gregory J., AbdulHameed, Mohamed Diwan M., Yu, Xueping, Kumar, Kamal, Ippolito, Danielle L., Lewis, John A., Stallings, Jonathan D., Wallqvist, Anders
Publicado 2014

Rare disease variant curation from literature: assessing gaps with creatine transport deficiency in focus

por Lyons, Erica L., Watson, Daniel, Alodadi, Mohammad S., Haugabook, Sharie J., Tawa, Gregory J., Hannah-Shmouni, Fady, Porter, Forbes D., Collins, Jack R., Ottinger, Elizabeth A., Mudunuri, Uma S.
Publicado 2023

Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational value for humans

por Mannheimer, Joshua D., Tawa, Gregory, Gerhold, David, Braisted, John, Sayers, Carly M., McEachron, Troy A., Meltzer, Paul, Mazcko, Christina, Beck, Jessica A., LeBlanc, Amy K.
Publicado 2023

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

por Kouznetsova, Jennifer, Sun, Wei, Martínez-Romero, Carles, Tawa, Gregory, Shinn, Paul, Chen, Catherine Z, Schimmer, Aaron, Sanderson, Philip, McKew, John C, Zheng, Wei, García-Sastre, Adolfo
Publicado 2014

Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines

por Kaewkhaw, Rossukon, Swaroop, Manju, Homma, Kohei, Nakamura, Jutaro, Brooks, Matthew, Kaya, Koray Dogan, Chaitankar, Vijender, Michael, Sam, Tawa, Gregory, Zou, Jizhong, Rao, Mahendra, Zheng, Wei, Cogliati, Tiziana, Swaroop, Anand
Publicado 2016

Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects

por Chen, Holly Y, Swaroop, Manju, Papal, Samantha, Mondal, Anupam K, Song, Hyun Beom, Campello, Laura, Tawa, Gregory J, Regent, Florian, Shimada, Hiroko, Nagashima, Kunio, de Val, Natalia, Jacobson, Samuel G, Zheng, Wei, Swaroop, Anand
Publicado 2023

Identification of Multiple Cryptococcal Fungicidal Drug Targets by Combined Gene Dosing and Drug Affinity Responsive Target Stability Screening

por Park, Yoon-Dong, Sun, Wei, Salas, Antonio, Antia, Avan, Carvajal, Cindy, Wang, Amy, Xu, Xin, Meng, Zhaojin, Zhou, Ming, Tawa, Gregory J., Dehdashti, Jean, Zheng, Wei, Henderson, Christina M., Zelazny, Adrian M., Williamson, Peter R.
Publicado 2016

Rapid Countermeasure Discovery against Francisella tularensis Based on a Metabolic Network Reconstruction

por Chaudhury, Sidhartha, Abdulhameed, Mohamed Diwan M., Singh, Narender, Tawa, Gregory J., D’haeseleer, Patrik M., Zemla, Adam T., Navid, Ali, Zhou, Carol E., Franklin, Matthew C., Cheung, Jonah, Rudolph, Michael J., Love, James, Graf, John F., Rozak, David A., Dankmeyer, Jennifer L., Amemiya, Kei, Daefler, Simon, Wallqvist, Anders
Publicado 2013