Extensive Expression Analysis of Htt Transcripts in Brain Regions from the zQ175 HD Mouse Model Using a QuantiGene Multiplex Assay

por Papadopoulou, Aikaterini S., Gomez-Paredes, Casandra, Mason, Michael A., Taxy, Bridget A., Howland, David, Bates, Gillian P.
Publicado 2019

The heat shock response, determined by QuantiGene multiplex, is impaired in HD mouse models and not caused by HSF1 reduction

por Gomez-Paredes, Casandra, Mason, Michael A., Taxy, Bridget A., Papadopoulou, Aikaterini S., Paganetti, Paolo, Bates, Gillian P.
Publicado 2021

Development of novel bioassays to detect soluble and aggregated Huntingtin proteins on three technology platforms

por Landles, Christian, Milton, Rebecca E, Jean, Alexandre, McLarnon, Stuart, McAteer, Sean J, Taxy, Bridget A, Osborne, Georgina F, Zhang, Chuangchuang, Duan, Wenzhen, Howland, David, Bates, Gillian P
Publicado 2021

Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington’s Disease Knock-in Mice

por Schindler, Franziska, Praedel, Nicole, Neuendorf, Nancy, Kunz, Severine, Schnoegl, Sigrid, Mason, Michael A., Taxy, Bridget A., Bates, Gillian P., Khoshnan, Ali, Priller, Josef, Grimm, Jan, Maier, Marcel, Boeddrich, Annett, Wanker, Erich E.
Publicado 2021

Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches

por Smith, Edward J, Sathasivam, Kirupa, Landles, Christian, Osborne, Georgina F, Mason, Michael A, Gomez-Paredes, Casandra, Taxy, Bridget A, Milton, Rebecca E, Ast, Anne, Schindler, Franziska, Zhang, Chuangchuang, Duan, Wenzhen, Wanker, Erich E, Bates, Gillian P
Publicado 2023

Alternative processing of human HTT mRNA with implications for Huntington’s disease therapeutics

por Fienko, Sandra, Landles, Christian, Sathasivam, Kirupa, McAteer, Sean J, Milton, Rebecca E, Osborne, Georgina F, Smith, Edward J, Jones, Samuel T, Bondulich, Marie K, Danby, Emily C E, Phillips, Jemima, Taxy, Bridget A, Kordasiewicz, Holly B, Bates, Gillian P
Publicado 2022