E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity

por Yoon, Jeehyun, Grinchuk, Oleg V., Tirado-Magallanes, Roberto, Ngian, Zhen Kai, Tay, Emmy Xue Yun, Chuah, You Heng, Lee, Bernice Woon Li, Feng, Jia, Crasta, Karen Carmelina, Ong, Chin Tong, Benoukraf, Touati, Ong, Derrick Sek Tong
Publicado 2022

CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma

por Chuah, You Heng, Tay, Emmy Xue Yun, Grinchuk, Oleg V., Yoon, Jeehyun, Feng, Jia, Kannan, Srinivasaraghavan, Robert, Matius, Jakhar, Rekha, Liang, Yajing, Lee, Bernice Woon Li, Wang, Loo Chien, Lim, Yan Ting, Zhao, Tianyun, Sobota, Radoslaw M., Lu, Guang, Low, Boon Chuan, Crasta, Karen Carmelina, Verma, Chandra Shekhar, Lin, Zhewang, Ong, Derrick Sek Tong
Publicado 2023

A chemical biology approach reveals a dependency of glioblastoma on biotin distribution

por Yoon, Jeehyun, Grinchuk, Oleg V., Kannan, Srinivasaraghavan, Ang, Melgious Jin Yan, Li, Zhenglin, Tay, Emmy Xue Yun, Lok, Ker Zhing, Lee, Bernice Woon Li, Chuah, You Heng, Chia, Kimberly, Tirado Magallanes, Roberto, Liu, Chenfei, Zhao, Haonan, Hor, Jin Hui, Lim, Jhin Jieh, Benoukraf, Touati, Toh, Tan Boon, Chow, Edward Kai-Hua, Kovalik, Jean-Paul, Ching, Jianhong, Ng, Shi-Yan, Koh, Ming Joo, Liu, Xiaogang, Verma, Chandra Shekhar, Ong, Derrick Sek Tong
Publicado 2021