HSV-1 single-cell analysis reveals the activation of anti-viral and developmental programs in distinct sub-populations

por Drayman, Nir, Patel, Parthiv, Vistain, Luke, Tay, Savaş
Publicado 2019

Computer vision reveals hidden variables underlying NF-κB activation in single cells

por Patel, Parthiv, Drayman, Nir, Liu, Ping, Bilgic, Mustafa, Tay, Savaş
Publicado 2021

Digital signaling decouples activation probability and population heterogeneity

por Kellogg, Ryan A, Tian, Chengzhe, Lipniacki, Tomasz, Quake, Stephen R, Tay, Savaş
Publicado 2015

Noise Induces Hopping between NF-κB Entrainment Modes

por Heltberg, Mathias, Kellogg, Ryan A., Krishna, Sandeep, Tay, Savaş, Jensen, Mogens H.
Publicado 2016

Spontaneous NF-κB Activation by Autocrine TNFα Signaling: A Computational Analysis

por Pękalski, Jakub, Zuk, Pawel J., Kochańczyk, Marek, Junkin, Michael, Kellogg, Ryan, Tay, Savaş, Lipniacki, Tomasz
Publicado 2013

High-Content Quantification of Single-Cell Immune Dynamics

por Junkin, Michael, Kaestli, Alicia J., Cheng, Zhang, Jordi, Christian, Albayrak, Cem, Hoffmann, Alexander, Tay, Savaş
Publicado 2016

Ultra-multiplexed analysis of single-cell dynamics reveals logic rules in differentiation

por Zhang, Ce, Tu, Hsiung-Lin, Jia, Gengjie, Mukhtar, Tanzila, Taylor, Verdon, Rzhetsky, Andrey, Tay, Savaş
Publicado 2019

Fixed single-cell RNA sequencing for understanding virus infection and host response

por Van Phan, Hoang, van Gent, Michiel, Drayman, Nir, Basu, Anindita, Gack, Michaela U., Tay, Savaş
Publicado 2021

High-throughput RNA sequencing of paraformaldehyde-fixed single cells

por Phan, Hoang Van, van Gent, Michiel, Drayman, Nir, Basu, Anindita, Gack, Michaela U., Tay, Savaş
Publicado 2021

A microfluidic device for measuring cell migration towards substrate-bound and soluble chemokine gradients

por Schwarz, Jan, Bierbaum, Veronika, Merrin, Jack, Frank, Tino, Hauschild, Robert, Bollenbach, Tobias, Tay, Savaş, Sixt, Michael, Mehling, Matthias
Publicado 2016

Spatiotemporal NF-κB dynamics encodes the position, amplitude, and duration of local immune inputs

por Son, Minjun, Frank, Tino, Holst-Hansen, Thomas, Wang, Andrew G., Junkin, Michael, Kashaf, Sara S., Trusina, Ala, Tay, Savaş
Publicado 2022

Discovery of SARS-CoV-2 main protease inhibitors using a synthesis-directed de novo design model

por Morris, Aaron, McCorkindale, William, Consortium, The COVID Moonshot, Drayman, Nir, Chodera, John D., Tay, Savaş, London, Nir, Lee, Alpha A.
Publicado 2021

Ultra-sensitive digital quantification of proteins and mRNA in single cells

por Lin, Jing, Jordi, Christian, Son, Minjun, Van Phan, Hoang, Drayman, Nir, Abasiyanik, Mustafa Fatih, Vistain, Luke, Tu, Hsiung-Lin, Tay, Savaş
Publicado 2019

Droplet-based high-throughput cultivation for accurate screening of antibiotic resistant gut microbes

por Watterson, William J, Tanyeri, Melikhan, Watson, Andrea R, Cham, Candace M, Shan, Yue, Chang, Eugene B, Eren, A Murat, Tay, Savaş
Publicado 2020

Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids

por Schuster, Brooke, Junkin, Michael, Kashaf, Sara Saheb, Romero-Calvo, Isabel, Kirby, Kori, Matthews, Jonathan, Weber, Christopher R., Rzhetsky, Andrey, White, Kevin P., Tay, Savaş
Publicado 2020

Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes

por Abasıyanık, M. Fatih, Wolfe, Krysta, Van Phan, Hoang, Lin, Jing, Laxman, Bharathi, White, Steven R., Verhoef, Philip A., Mutlu, Gökhan M., Patel, Bhakti, Tay, Savaş
Publicado 2020

OrganoID: A versatile deep learning platform for tracking and analysis of single-organoid dynamics

por Matthews, Jonathan M., Schuster, Brooke, Kashaf, Sara Saheb, Liu, Ping, Ben-Yishay, Rakefet, Ishay-Ronen, Dana, Izumchenko, Evgeny, Shen, Le, Weber, Christopher R., Bielski, Margaret, Kupfer, Sonia S., Bilgic, Mustafa, Rzhetsky, Andrey, Tay, Savaş
Publicado 2022

Discovery of New States of Immunomodulation for Vaccine Adjuvants via High Throughput Screening: Expanding Innate Responses to PRRs

por Kim, Jeremiah Y., Rosenberger, Matthew G., Chen, Siquan, IP, Carman KM, Bahmani, Azadeh, Chen, Qing, Shen, Jinjing, Tang, Yifeng, Wang, Andrew, Kenna, Emma, Son, Minjun, Tay, Savaş, Ferguson, Andrew L., Esser-Kahn, Aaron P.
Publicado 2023

Measuring SARS‐CoV‐2 aerosolization in rooms of hospitalized patients

por Yan, Kenneth, Lin, Jing, Albaugh, Shaley, Yang, Meredith, Wang, Esther, Cyberski, Thomas, Abasiyanik, Mustafa Fatih, Wroblewski, Kristen E., O'Connor, Michael, Klock, Allan, Tung, Avery, Shahul, Sajid, Kurian, Dinesh, Tay, Savaş, Pinto, Jayant M.
Publicado 2022

Development of Masitinib Derivatives with Enhanced M(pro) Ligand Efficiency and Reduced Cytotoxicity

por Menendez, Cintia A., Mohamed, Adil, Perez-Lemus, Gustavo R., Weiss, Adam M., Rawe, Benjamin W., Liu, Guancen, Crolais, Alex E., Kenna, Emma, Byléhn, Fabian, Alvarado, Walter, Mendels, Dan, Rowan, Stuart J., Tay, Savaş, de Pablo, Juan J.
Publicado 2023