Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma

por Fairfax, Benjamin P, Taylor, Chelsea A, Watson, Robert A, Nassiri, Isar, Danielli, Sara, Fang, Hai, Mahé, Elise A, Cooper, Rosalin, Woodcock, Victoria, Traill, Zoe, Al-Mossawi, M Hussein, Knight, Julian C, Klenerman, Paul, Payne, Miranda, Middleton, Mark R
Publicado 2020

Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele

por Al-Mossawi, Hussein, Yager, Nicole, Taylor, Chelsea A., Lau, Evelyn, Danielli, Sara, de Wit, Jelle, Gilchrist, James, Nassiri, Isar, Mahe, Elise A., Lee, Wanseon, Rizvi, Laila, Makino, Seiko, Cheeseman, Jane, Neville, Matt, Knight, Julian C., Bowness, Paul, Fairfax, Benjamin P.
Publicado 2019

Checkpoint-blocker-induced autoimmunity is associated with favourable outcome in metastatic melanoma and distinct T-cell expression profiles

por Ye, Weiyu, Olsson-Brown, Anna, Watson, Robert A., Cheung, Vincent T. F., Morgan, Robert D., Nassiri, Isar, Cooper, Rosalin, Taylor, Chelsea A., Akbani, Umair, Brain, Oliver, Matin, Rubeta N., Coupe, Nicholas, Middleton, Mark R., Coles, Mark, Sacco, Joseph J., Payne, Miranda J., Fairfax, Benjamin P.
Publicado 2021

Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity

por Gilchrist, James J., Makino, Seiko, Naranbhai, Vivek, Sharma, Piyush K., Koturan, Surya, Tong, Orion, Taylor, Chelsea A., Watson, Robert A., de los Aires, Alba Verge, Cooper, Rosalin, Lau, Evelyn, Danielli, Sara, Hameiri-Bowen, Dan, Lee, Wanseon, Ng, Esther, Whalley, Justin, Knight, Julian C., Fairfax, Benjamin P.
Publicado 2022

IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma

por Taylor, Chelsea A., Watson, Robert A., Tong, Orion, Ye, Weiyu, Nassiri, Isar, Gilchrist, James J., de los Aires, Alba Verge, Sharma, Piyush Kumar, Koturan, Surya, Cooper, Rosalin A., Woodcock, Victoria K., Jungkurth, Elsita, Shine, Brian, Coupe, Nicholas, Payne, Miranda J., Church, David N., Naranbhai, Vivek, Groha, Stefan, Emery, Paul, Mankia, Kulveer, Freedman, Matthew L., Choueiri, Toni K., Middleton, Mark R., Gusev, Alexander, Fairfax, Benjamin P.
Publicado 2022

TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer

por Beatson, Richard E., Parente-Pereira, Ana C., Halim, Leena, Cozzetto, Domenico, Hull, Caroline, Whilding, Lynsey M., Martinez, Olivier, Taylor, Chelsea A., Obajdin, Jana, Luu Hoang, Kim Ngan, Draper, Benjamin, Iqbal, Ayesha, Hardiman, Tom, Zabinski, Tomasz, Man, Francis, de Rosales, Rafael T.M., Xie, Jinger, Aswad, Fred, Achkova, Daniela, Joseph, Chung-Yang Ricardo, Ciprut, Sara, Adami, Antonella, Roider, Helge G., Hess-Stumpp, Holger, Győrffy, Balázs, Quist, Jelmar, Grigoriadis, Anita, Sommer, Anette, Tutt, Andrew N.J., Davies, David M., Maher, John
Publicado 2021

An immunodominant NP(105–113)-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

por Peng, Yanchun, Felce, Suet Ling, Dong, Danning, Penkava, Frank, Mentzer, Alexander J., Yao, Xuan, Liu, Guihai, Yin, Zixi, Chen, Ji-Li, Lu, Yongxu, Wellington, Dannielle, Wing, Peter A. C., Dominey-Foy, Delaney C. C., Jin, Chen, Wang, Wenbo, Hamid, Megat Abd, Fernandes, Ricardo A., Wang, Beibei, Fries, Anastasia, Zhuang, Xiaodong, Ashley, Neil, Rostron, Timothy, Waugh, Craig, Sopp, Paul, Hublitz, Philip, Beveridge, Ryan, Tan, Tiong Kit, Dold, Christina, Kwok, Andrew J., Rich-Griffin, Charlotte, Dejnirattisa, Wanwisa, Liu, Chang, Kurupati, Prathiba, Nassiri, Isar, Watson, Robert A., Tong, Orion, Taylor, Chelsea A., Kumar Sharma, Piyush, Sun, Bo, Curion, Fabiola, Revale, Santiago, Garner, Lucy C., Jansen, Kathrin, Ferreira, Ricardo C., Attar, Moustafa, Fry, Jeremy W., Russell, Rebecca A., Stauss, Hans J., James, William, Townsend, Alain, Ho, Ling-Pei, Klenerman, Paul, Mongkolsapaya, Juthathip, Screaton, Gavin R., Dendrou, Calliope, Sansom, Stephen N., Bashford-Rogers, Rachael, Chain, Benny, Smith, Geoffrey L., McKeating, Jane A., Fairfax, Benjamin P., Bowness, Paul, McMichael, Andrew J., Ogg, Graham, Knight, Julian C., Dong, Tao
Publicado 2021