The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa

por Taylor, Isabelle R., Jeffrey, Philip D., Moustafa, Dina A., Goldberg, Joanna B., Bassler, Bonnie L.
Publicado 2022

Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein–Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor...

por Taylor, Isabelle R., Paczkowski, Jon E., Jeffrey, Philip D., Henke, Brad R., Smith, Chari D., Bassler, Bonnie L.
Publicado 2021

The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in Pseudomonas aeruginosa

por Simanek, Kayla A., Taylor, Isabelle R., Richael, Erica K., Lasek-Nesselquist, Erica, Bassler, Bonnie L., Paczkowski, Jon E.
Publicado 2022

Protein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa

por Taylor, Isabelle R., Murray-Nerger, Laura A., Greco, Todd M., Liu, Dawei, Cristea, Ileana M., Bassler, Bonnie L.
Publicado 2022

Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells

por Taylor, Isabelle R., Assimon, Victoria A., Kuo, Szu Yu, Rinaldi, Silvia, Li, Xiaokai, Young, Zapporah T., Morra, Giulia, Green, Keith, Nguyen, Daniel, Shao, Hao, Garneau-Tsodikova, Sylvie, Colombo, Giorgio, Gestwicki, Jason E.
Publicado 2020