Targeting the Sphingolipid System as a Therapeutic Direction for Glioblastoma

por Tea, Melinda N., Poonnoose, Santosh I., Pitson, Stuart M.
Publicado 2020

Characterising Distinct Migratory Profiles of Infiltrating T-Cell Subsets in Human Glioblastoma

por Kollis, Paris M., Ebert, Lisa M., Toubia, John, Bastow, Cameron R., Ormsby, Rebecca J., Poonnoose, Santosh I., Lenin, Sakthi, Tea, Melinda N., Pitson, Stuart M., Gomez, Guillermo A., Brown, Michael P., Gargett, Tessa
Publicado 2022

A Drug Screening Pipeline Using 2D and 3D Patient-Derived In Vitro Models for Pre-Clinical Analysis of Therapy Response in Glioblastoma

por Lenin, Sakthi, Ponthier, Elise, Scheer, Kaitlin G., Yeo, Erica C. F., Tea, Melinda N., Ebert, Lisa M., Oksdath Mansilla, Mariana, Poonnoose, Santosh, Baumgartner, Ulrich, Day, Bryan W., Ormsby, Rebecca J., Pitson, Stuart M., Gomez, Guillermo A.
Publicado 2021

Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition

por Bennett, Melissa K., Li, Manjun, Tea, Melinda N., Pitman, Melissa R., Toubia, John, Wang, Paul P.-S., Anderson, Dovile, Creek, Darren J., Orlowski, Robert Z., Gliddon, Briony L., Powell, Jason A., Wallington-Beddoe, Craig T., Pitson, Stuart M.
Publicado 2021

Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma

por Neubauer, Heidi A., Tea, Melinda N., Zebol, Julia R., Gliddon, Briony L., Stefanidis, Cassandra, Moretti, Paul A. B., Pitman, Melissa R., Costabile, Maurizio, Kular, Jasreen, Stringer, Brett W., Day, Bryan W., Samuel, Michael S., Bonder, Claudine S., Powell, Jason A., Pitson, Stuart M.
Publicado 2018

GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma

por Gargett, Tessa, Ebert, Lisa M, Truong, Nga T H, Kollis, Paris M, Sedivakova, Kristyna, Yu, Wenbo, Yeo, Erica C F, Wittwer, Nicole L, Gliddon, Briony L, Tea, Melinda N, Ormsby, Rebecca, Poonnoose, Santosh, Nowicki, Jake, Vittorio, Orazio, Ziegler, David S, Pitson, Stuart M, Brown, Michael P
Publicado 2022

3D-printed microplate inserts for long term high-resolution imaging of live brain organoids

por Oksdath Mansilla, Mariana, Salazar-Hernandez, Camilo, Perrin, Sally L., Scheer, Kaitlin G., Cildir, Gökhan, Toubia, John, Sedivakova, Kristyna, Tea, Melinda N., Lenin, Sakthi, Ponthier, Elise, Yeo, Erica C. F., Tergaonkar, Vinay, Poonnoose, Santosh, Ormsby, Rebecca J., Pitson, Stuart M., Brown, Michael P., Ebert, Lisa M., Gomez, Guillermo A.
Publicado 2021

Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy

por Ebert, Lisa M, Yu, Wenbo, Gargett, Tessa, Toubia, John, Kollis, Paris M, Tea, Melinda N, Ebert, Brenton W, Bardy, Cedric, van den Hurk, Mark, Bonder, Claudine S, Manavis, Jim, Ensbey, Kathleen S, Oksdath Mansilla, Mariana, Scheer, Kaitlin G, Perrin, Sally L, Ormsby, Rebecca J, Poonnoose, Santosh, Koszyca, Barbara, Pitson, Stuart M, Day, Bryan W, Gomez, Guillermo A, Brown, Michael P
Publicado 2020

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia

por Lewis, Alexander C., Pope, Victoria S., Tea, Melinda N., Li, Manjun, Nwosu, Gus O., Nguyen, Thao M., Wallington-Beddoe, Craig T., Moretti, Paul A. B., Anderson, Dovile, Creek, Darren J., Costabile, Maurizio, Ali, Saira R., Thompson-Peach, Chloe A. L., Dredge, B. Kate, Bert, Andrew G., Goodall, Gregory J., Ekert, Paul G., Brown, Anna L., D’Andrea, Richard, Robinson, Nirmal, Pitman, Melissa R., Thomas, Daniel, Ross, David M., Gliddon, Briony L., Powell, Jason A., Pitson, Stuart M.
Publicado 2022