Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn(2+)

por Sychantha, David, Rotondo, Caitlyn M., Tehrani, Kamaleddin H.M.E., Martin, Nathaniel I., Wright, Gerard D.
Publicado 2021

Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition

por Wade, Nicola, Tehrani, Kamaleddin H. M. E., Brüchle, Nora C., van Haren, Matthijs J., Mashayekhi, Vida, Martin, Nathaniel I.
Publicado 2021

Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem

por Tehrani, Kamaleddin H. M. E., Brüchle, Nora C., Wade, Nicola, Mashayekhi, Vida, Pesce, Diego, van Haren, Matthijs J., Martin, Nathaniel I.
Publicado 2020

Cephalosporin Prodrug Inhibitors Overcome Metallo‐β‐Lactamase Driven Antibiotic Resistance

por van Haren, Matthijs J., Tehrani, Kamaleddin H. M. E., Kotsogianni, Ioli, Wade, Nicola, Brüchle, Nora C., Mashayekhi, Vida, Martin, Nathaniel I.
Publicado 2021

Novel Carbapenemases FLC-1 and IMI-2 Encoded by an Enterobacter cloacae Complex Isolated from Food Products

por Brouwer, Michael S. M., Tehrani, Kamaleddin H. M. E., Rapallini, Michel, Geurts, Yvon, Kant, Arie, Harders, Frank, Mashayekhi, Vida, Martin, Nathaniel I., Bossers, Alex, Mevius, Dik J., Wit, Ben, Veldman, Kees T.
Publicado 2019

Novel Cephalosporin Conjugates Display Potent and Selective Inhibition of Imipenemase-Type Metallo-β-Lactamases

por Tehrani, Kamaleddin H. M. E., Wade, Nicola, Mashayekhi, Vida, Brüchle, Nora C., Jespers, Willem, Voskuil, Koen, Pesce, Diego, van Haren, Matthijs J., van Westen, Gerard J. P., Martin, Nathaniel I.
Publicado 2021

Darobactins Exhibiting Superior Antibiotic Activity by Cryo‐EM Structure Guided Biosynthetic Engineering

por Seyfert, Carsten E., Porten, Christoph, Yuan, Biao, Deckarm, Selina, Panter, Fabian, Bader, Chantal D., Coetzee, Janetta, Deschner, Felix, Tehrani, Kamaleddin H. M. E., Higgins, Paul G., Seifert, Harald, Marlovits, Thomas C., Herrmann, Jennifer, Müller, Rolf
Publicado 2022