A high-throughput screen to identify novel synthetic lethal compounds for the treatment of E-cadherin-deficient cells

por Beetham, Henry, Chen, Augustine, Telford, Bryony J., Single, Andrew, Jarman, Kate E., Lackovic, Kurt, Luxenburger, Andreas, Guilford, Parry
Publicado 2019

E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition

por Chen, Augustine, Beetham, Henry, Black, Michael A, Priya, Rashmi, Telford, Bryony J, Guest, Joanne, Wiggins, George A R, Godwin, Tanis D, Yap, Alpha S, Guilford, Parry J
Publicado 2014

Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic

por van den Bosch, Marion T.J., Yahyanejad, Sanaz, Alemdehy, Mir Farshid, Telford, Bryony J., de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Stegink, Marieke, van Pinxteren, Laurens A.H., Schaapveld, Roel Q.J., Janicot, Michel
Publicado 2021

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology

por Telford, Bryony J., Yahyanejad, Sanaz, de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Stegink, Marieke, van den Bosch, Marion T.J., Alemdehy, Mir Farshid, van Pinxteren, Laurens A.H., Schaapveld, Roel Q.J., Janicot, Michel
Publicado 2021

E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function

por Godwin, Tanis D., Kelly, S. Thomas, Brew, Tom P., Bougen-Zhukov, Nicola M., Single, Andrew B., Chen, Augustine, Stylianou, Cassie E., Harris, Lawrence D., Currie, Sophie K., Telford, Bryony J., Beetham, Henry G., Evans, Gary B., Black, Michael A., Guilford, Parry J.
Publicado 2018