Incorporation of a Novel CD4+ Helper Epitope Identified from Aquifex aeolicus Enhances Humoral Responses Induced by DNA and Protein Vaccinations

por Xu, Ziyang, Chokkalingam, Neethu, Tello-Ruiz, Edgar, Walker, Susanne, Kulp, Daniel W., Weiner, David B.
Publicado 2020

Synthetic DNA delivery by electroporation promotes robust in vivo sulfation of broadly neutralizing anti-HIV immunoadhesin eCD4-Ig

por Xu, Ziyang, Wise, Megan C., Choi, Hyeree, Perales-Puchalt, Alfredo, Patel, Ami, Tello-Ruiz, Edgar, Chu, Jacqueline D., Muthumani, Kar, Weiner, David B.
Publicado 2018

Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression in vivo

por Tursi, Nicholas J., Xu, Ziyang, Helble, Michaela, Walker, Susanne, Liaw, Kevin, Chokkalingam, Neethu, Kannan, Toshitha, Wu, Yuanhan, Tello-Ruiz, Edgar, Park, Daniel H., Zhu, Xizhou, Wise, Megan C., Smith, Trevor R. F., Majumdar, Sonali, Kossenkov, Andrew, Kulp, Daniel W., Weiner, David B.
Publicado 2023

Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv...

por Xu, Ziyang, Wise, Megan C., Chokkalingam, Neethu, Walker, Susanne, Tello‐Ruiz, Edgar, Elliott, Sarah T. C., Perales‐Puchalt, Alfredo, Xiao, Peng, Zhu, Xizhou, Pumroy, Ruth A., Fisher, Paul D., Schultheis, Katherine, Schade, Eric, Menis, Sergey, Guzman, Stacy, Andersen, Hanne, Broderick, Kate E., Humeau, Laurent M., Muthumani, Kar, Moiseenkova‐Bell, Vera, Schief, William R., Weiner, David B., Kulp, Daniel W.
Publicado 2020

In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity

por Xu, Ziyang, Wise, Megan C., Chokkalingam, Neethu, Walker, Susanne, Tello‐Ruiz, Edgar, Elliott, Sarah T. C., Perales‐Puchalt, Alfredo, Xiao, Peng, Zhu, Xizhou, Pumroy, Ruth A., Fisher, Paul D., Schultheis, Katherine, Schade, Eric, Menis, Sergey, Guzman, Stacy, Andersen, Hanne, Broderick, Kate E., Humeau, Laurent M., Muthumani, Kar, Moiseenkova‐Bell, Vera, Schief, William R., Weiner, David B., Kulp, Daniel W.
Publicado 2020

Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer

por Xu, Ziyang, Walker, Susanne, Wise, Megan C., Chokkalingam, Neethu, Purwar, Mansi, Moore, Alan, Tello-Ruiz, Edgar, Wu, Yuanhan, Majumdar, Sonali, Konrath, Kylie M., Kulkarni, Abhijeet, Tursi, Nicholas J., Zaidi, Faraz I., Reuschel, Emma L., Patel, Ishaan, Obeirne, April, Du, Jianqiu, Schultheis, Katherine, Gites, Lauren, Smith, Trevor, Mendoza, Janess, Broderick, Kate E., Humeau, Laurent, Pallesen, Jesper, Weiner, David B., Kulp, Daniel W.
Publicado 2022

Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model

por Patel, Ami, Walters, Jewell N., Reuschel, Emma L., Schultheis, Katherine, Parzych, Elizabeth, Gary, Ebony N., Maricic, Igor, Purwar, Mansi, Eblimit, Zeena, Walker, Susanne N., Guimet, Diana, Bhojnagarwala, Pratik, Adeniji, Opeyemi S., Doan, Arthur, Xu, Ziyang, Elwood, Dustin, Reeder, Sophia M., Pessaint, Laurent, Kim, Kevin Y., Cook, Anthony, Chokkalingam, Neethu, Finneyfrock, Brad, Tello-Ruiz, Edgar, Dodson, Alan, Choi, Jihae, Generotti, Alison, Harrison, John, Tursi, Nicholas J., Andrade, Viviane M., Dia, Yaya, Zaidi, Faraz I., Andersen, Hanne, Abdel-Mohsen, Mohamed, Lewis, Mark G., Muthumani, Kar, Kim, J. Joseph, Kulp, Daniel W., Humeau, Laurent M., Ramos, Stephanie J., Smith, Trevor R.F., Weiner, David B., Broderick, Kate E.
Publicado 2021

Immunogenicity of a DNA vaccine candidate for COVID-19

por Smith, Trevor R. F., Patel, Ami, Ramos, Stephanie, Elwood, Dustin, Zhu, Xizhou, Yan, Jian, Gary, Ebony N., Walker, Susanne N., Schultheis, Katherine, Purwar, Mansi, Xu, Ziyang, Walters, Jewell, Bhojnagarwala, Pratik, Yang, Maria, Chokkalingam, Neethu, Pezzoli, Patrick, Parzych, Elizabeth, Reuschel, Emma L., Doan, Arthur, Tursi, Nicholas, Vasquez, Miguel, Choi, Jihae, Tello-Ruiz, Edgar, Maricic, Igor, Bah, Mamadou A., Wu, Yuanhan, Amante, Dinah, Park, Daniel H., Dia, Yaya, Ali, Ali Raza, Zaidi, Faraz I., Generotti, Alison, Kim, Kevin Y., Herring, Timothy A., Reeder, Sophia, Andrade, Viviane M., Buttigieg, Karen, Zhao, Gan, Wu, Jiun-Ming, Li, Dan, Bao, Linlin, Liu, Jiangning, Deng, Wei, Qin, Chuan, Brown, Ami Shah, Khoshnejad, Makan, Wang, Nianshuang, Chu, Jacqueline, Wrapp, Daniel, McLellan, Jason S., Muthumani, Kar, Wang, Bin, Carroll, Miles W., Kim, J. Joseph, Boyer, Jean, Kulp, Daniel W., Humeau, Laurent M. P. F., Weiner, David B., Broderick, Kate E.
Publicado 2020