Mutation Signatures Including APOBEC in Cancer Cell Lines

por Jarvis, Matthew C, Ebrahimi, Diako, Temiz, Nuri A, Harris, Reuben S
Publicado 2018

The Role of Methylation in the Intrinsic Dynamics of B- and Z-DNA

por Temiz, Nuri A., Donohue, Duncan E., Bacolla, Albino, Luke, Brian T., Collins, Jack R.
Publicado 2012

OR16-2 Steroid Receptor Co-Activator Complexes Regulate Metabolic PFKFB Enzymes to Drive Therapy Resistant ER+ Breast Cancer

por Benner, Elizabeth, Dos Santos, Camila, Hagen, Kyla, Lange, Carol, Ostrander, Julie, Temiz, Nuri, Trousdell, Marygrace, Truong, Thu
Publicado 2022

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

por Temiz, Nuri A., Moriarity, Branden S., Wolf, Natalie K., Riordan, Jesse D., Dupuy, Adam J., Largaespada, David A., Sarver, Aaron L.
Publicado 2016

Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B

por Akre, Monica K., Starrett, Gabriel J., Quist, Jelmar S., Temiz, Nuri A., Carpenter, Michael A., Tutt, Andrew N. J., Grigoriadis, Anita, Harris, Reuben S.
Publicado 2016

Human Papillomavirus E6 Triggers Upregulation of the Antiviral and Cancer Genomic DNA Deaminase APOBEC3B

por Vieira, Valdimara C., Leonard, Brandon, White, Elizabeth A., Starrett, Gabriel J., Temiz, Nuri A., Lorenz, Laurel D., Lee, Denis, Soares, Marcelo A., Lambert, Paul F., Howley, Peter M., Harris, Reuben S.
Publicado 2014

The somatic autosomal mutation matrix in cancer genomes

por Temiz, Nuri A., Donohue, Duncan E., Bacolla, Albino, Vasquez, Karen M., Cooper, David N., Mudunuri, Uma, Ivanic, Joseph, Cer, Regina Z., Yi, Ming, Stephens, Robert M., Collins, Jack R., Luke, Brian T.
Publicado 2015

Erratum to: The somatic autosomal mutation matrix in cancer genomes

por Temiz, Nuri A., Donohue, Duncan E., Bacolla, Albino, Vasquez, Karen M., Cooper, David N., Mudunuri, Uma, Ivanic, Joseph, Cer, Regina Z., Yi, Ming, Stephens, Robert M., Collins, Jack R., Luke, Brian T.
Publicado 2015

The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis

por Starrett, Gabriel J., Luengas, Elizabeth M., McCann, Jennifer L., Ebrahimi, Diako, Temiz, Nuri A., Love, Robin P., Feng, Yuqing, Adolph, Madison B., Chelico, Linda, Law, Emily K., Carpenter, Michael A., Harris, Reuben S
Publicado 2016

Non-B DB v2.0: a database of predicted non-B DNA-forming motifs and its associated tools

por Cer, Regina Z., Donohue, Duncan E., Mudunuri, Uma S., Temiz, Nuri A., Loss, Michael A., Starner, Nathan J., Halusa, Goran N., Volfovsky, Natalia, Yi, Ming, Luke, Brian T., Bacolla, Albino, Collins, Jack R., Stephens, Robert M.
Publicado 2013

Steroid Receptor Co-Activators Regulate Metabolic Kinases to Drive Therapy Resistant ER+ Breast Cancer

por Truong, Thu Ha, Benner, Elizabeth A, Hagen, Kyla M, Temiz, Nuri A, Kerkvliet, Carlos Perez, Wang, Ying, Cortes-Sanchez, Emilio, Yang, Chieh-Hsiang, Pengo, Thomas, Guillen, Katrin P, Welm, Bryan E, Telang, Sucheta, Lange, Carol A, Ostrander, Julie Hanson
Publicado 2021

Guanine Holes Are Prominent Targets for Mutation in Cancer and Inherited Disease

por Bacolla, Albino, Temiz, Nuri A., Yi, Ming, Ivanic, Joseph, Cer, Regina Z., Donohue, Duncan E., Ball, Edward V., Mudunuri, Uma S., Wang, Guliang, Jain, Aklank, Volfovsky, Natalia, Luke, Brian T., Stephens, Robert M., Cooper, David N., Collins, Jack R., Vasquez, Karen M.
Publicado 2013

Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases

por Durfee, Cameron, Temiz, Nuri Alpay, Levin-Klein, Rena, Argyris, Prokopios P., Alsøe, Lene, Carracedo, Sergio, de la Vega, Alicia Alonso, Proehl, Joshua, Holzhauer, Anna M., Seeman, Zachary J., Lin, Yu-Hsiu T., Vogel, Rachel I., Sotillo, Rocio, Nilsen, Hilde, Harris, Reuben S.
Publicado 2023

DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo

por Naumann, Jordan A., Argyris, Prokopios P., Carpenter, Michael A., Gupta, Harshita B., Chen, Yanjun, Temiz, Nuri A., Zhou, Yufan, Durfee, Cameron, Proehl, Joshua, Koniar, Brenda L., Conticello, Silvestro G., Largaespada, David A., Brown, William L., Aihara, Hideki, Vogel, Rachel I., Harris, Reuben S.
Publicado 2023

Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases

por Durfee, Cameron, Temiz, Nuri Alpay, Levin-Klein, Rena, Argyris, Prokopios P., Alsøe, Lene, Carracedo, Sergio, Alonso de la Vega, Alicia, Proehl, Joshua, Holzhauer, Anna M., Seeman, Zachary J., Liu, Xingyu, Lin, Yu-Hsiu T., Vogel, Rachel I., Sotillo, Rocio, Nilsen, Hilde, Harris, Reuben S.
Publicado 2023

Acute expression of human APOBEC3B in mice results in RNA editing and lethality

por Alonso de la Vega, Alicia, Temiz, Nuri Alpay, Tasakis, Rafail, Somogyi, Kalman, Salgueiro, Lorena, Zimmer, Eleni, Ramos, Maria, Diaz-Jimenez, Alberto, Chocarro, Sara, Fernández-Vaquero, Mirian, Stefanovska, Bojana, Reuveni, Eli, Ben-David, Uri, Stenzinger, Albrecht, Poth, Tanja, Heikenwälder, Mathias, Papavasiliou, Nina, Harris, Reuben S., Sotillo, Rocio
Publicado 2023

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer

por Law, Emily K., Sieuwerts, Anieta M., LaPara, Kelly, Leonard, Brandon, Starrett, Gabriel J., Molan, Amy M., Temiz, Nuri A., Vogel, Rachel Isaksson, Meijer-van Gelder, Marion E., Sweep, Fred C. G. J., Span, Paul N., Foekens, John A., Martens, John W. M., Yee, Douglas, Harris, Reuben S.
Publicado 2016

PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER+ breast cancer

por Truong, Thu H., Benner, Elizabeth A., Hagen, Kyla M., Temiz, Nuri A., Kerkvliet, Carlos Perez, Wang, Ying, Cortes-Sanchez, Emilio, Yang, Chieh-Hsiang, Trousdell, Marygrace C., Pengo, Thomas, Guillen, Katrin P., Welm, Bryan E., Dos Santos, Camila O., Telang, Sucheta, Lange, Carol A., Ostrander, Julie H.
Publicado 2021

R‐spondin 2 Drives Liver Tumor Development in a Yes‐Associated Protein‐Dependent Manner

por Conboy, Caitlin B., Vélez‐Reyes, Germán L., Tschida, Barbara R., Hu, Hsiangyu, Kaufmann, Gabriel, Koes, Nicholas, Keller, Bryant, Alsinet, Clara, Cornellà, Helena, Pinyol, Roser, Abrahante, Juan E., Temiz, Nuri A., Linden, Michael A., Amin, Khalid, Kuka, Timothy P., Keng, Vincent W., Llovet, Josep M., Starr, Timothy K., Largaespada, David A.
Publicado 2019

APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer

por McCann, Jennifer L., Cristini, Agnese, Law, Emily K., Lee, Seo Yun, Tellier, Michael, Carpenter, Michael A., Beghè, Chiara, Kim, Jae Jin, Sanchez, Anthony, Jarvis, Matthew C., Stefanovska, Bojana, Temiz, Nuri A., Bergstrom, Erik N., Salamango, Daniel J., Brown, Margaret R., Murphy, Shona, Alexandrov, Ludmil B., Miller, Kyle M., Gromak, Natalia, Harris, Reuben S.
Publicado 2023