Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation

por Fan, Rong, Tenner, Andrea J
Publicado 2005

A Commentary On: “NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease”. A cautionary note regarding...

por Woodruff, Trent M., Tenner, Andrea J.
Publicado 2015

The good, the bad, and the opportunities of the complement system in neurodegenerative disease

por Schartz, Nicole D., Tenner, Andrea J.
Publicado 2020

Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics

por Garred, Peter, Tenner, Andrea J., Mollnes, Tom E.
Publicado 2021

Complement Nomenclature—Deconvoluted

por Bohlson, Suzanne S., Garred, Peter, Kemper, Claudia, Tenner, Andrea J.
Publicado 2019

The Role of Complement in Synaptic Pruning and Neurodegeneration

por Gomez-Arboledas, Angela, Acharya, Munjal M, Tenner, Andrea J
Publicado 2021

Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology

por Fonseca, Maria I, McGuire, Susan O, Counts, Scott E, Tenner, Andrea J
Publicado 2013

C5a Increases the Injury to Primary Neurons Elicited by Fibrillar Amyloid Beta

por Hernandez, Michael X., Namiranian, Pouya, Nguyen, Eric, Fonseca, Maria I., Tenner, Andrea J.
Publicado 2017

Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer’s mouse models

por Petrisko, Tiffany J., Gargus, Matthew, Chu, Shu-Hui, Selvan, Purnika, Whiteson, Katrine L., Tenner, Andrea J.
Publicado 2023

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

por Cribbs, David H, Berchtold, Nicole C, Perreau, Victoria, Coleman, Paul D, Rogers, Joseph, Tenner, Andrea J, Cotman, Carl W
Publicado 2012

Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease

por Fonseca, Maria I, Chu, Shu-Hui, Berci, Alisia M, Benoit, Marie E, Peters, Douglas G, Kimura, Yuko, Tenner, Andrea J
Publicado 2011

C5aR1 signaling promotes region and age dependent synaptic pruning in models of Alzheimer’s Disease

por Gomez-Arboledas, Angela, Fonseca, Maria I., Kramar, Enikö, Chu, Shu-Hui, Schartz, Nicole, Selvan, Purnika, Wood, Marcelo A., Tenner, Andrea J.
Publicado 2023

A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state

por Zekavat, Ghazal, Mozaffari, Raha, Arias, Vanessa J., Rostami, Susan Y., Badkerhanian, Armen, Tenner, Andrea J., Nichols, Kim E., Naji, Ali, Noorchashm, Hooman
Publicado 2010

Novel Aβ peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease

por Zhou, Jun, Fonseca, Maria I, Kayed, Rakez, Hernandez, Irma, Webster, Scott D, Yazan, Ozkan, Cribbs, David H, Glabe, Charles G, Tenner, Andrea J
Publicado 2005

Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain

por Fonseca, Maria I., Chu, Shu-Hui, Hernandez, Michael X., Fang, Melody J., Modarresi, Lila, Selvan, Pooja, MacGregor, Grant R., Tenner, Andrea J.
Publicado 2017

Impact of COVID‐19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research

por Gordon, Marcia N., Heneka, Michael T., Le Page, Lydia M., Limberger, Christian, Morgan, David, Tenner, Andrea J., Terrando, Niccolò, Willette, Auriel A., Willette, Sara A.
Publicado 2021

C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer’s model

por Schartz, Nicole D., Liang, Heidi Y., Carvalho, Klebea, Chu, Shu-Hui, Mendoza-Arvilla, Adrian, Petrisko, Tiffany J., Gomez-Arboledas, Angela, Mortazavi, Ali, Tenner, Andrea J.
Publicado 2023

Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer’s disease

por Zhang, Hai, Chen, Lujia, Johnston, Kevin G., Crapser, Joshua, Green, Kim N., Ha, Nicole My-Linh, Tenner, Andrea J., Holmes, Todd C., Nitz, Douglas A., Xu, Xiangmin
Publicado 2023

Analysis of the Putative Role of CR1 in Alzheimer’s Disease: Genetic Association, Expression and Function

por Fonseca, Maria I., Chu, Shuhui, Pierce, Aimee L., Brubaker, William D., Hauhart, Richard E., Mastroeni, Diego, Clarke, Elizabeth V., Rogers, Joseph, Atkinson, John P., Tenner, Andrea J.
Publicado 2016

Modulation of C5a–C5aR1 signaling alters the dynamics of AD progression

por Carvalho, Klebea, Schartz, Nicole D., Balderrama-Gutierrez, Gabriela, Liang, Heidi Y., Chu, Shu-Hui, Selvan, Purnika, Gomez-Arboledas, Angela, Petrisko, Tiffany J., Fonseca, Maria I., Mortazavi, Ali, Tenner, Andrea J.
Publicado 2022