Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion

por Tenor, Jennifer L., Oehlers, Stefan H., Yang, Jialu L., Tobin, David M., Perfect, John R.
Publicado 2015

605. Efficacy and pharmacokinetics-pharmacodynamics of ATI-2307 in a rabbit model of cryptococcal meningoencephalitis

por Giamberardino, Charles D, Tenor, Jennifer L, Toffaletti, Dena, Palmucci, Julia R, Cilla, Don, Hope, William, Perfect, John R
Publicado 2022

Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel...

por Miao, Yi, Tenor, Jennifer L., Toffaletti, Dena L., Maskarinec, Stacey A., Liu, Jiuyu, Lee, Richard E., Perfect, John R., Brennan, Richard G.
Publicado 2017

Amoeba Predation of Cryptococcus neoformans Results in Pleiotropic Changes to Traits Associated with Virulence

por Fu, Man Shun, Liporagi-Lopes, Livia C., dos Santos, Samuel R., Tenor, Jennifer L., Perfect, John R., Cuomo, Christina A., Casadevall, Arturo
Publicado 2021

Gene Expression of Diverse Cryptococcus Isolates during Infection of the Human Central Nervous System

por Yu, Chen-Hsin, Sephton-Clark, Poppy, Tenor, Jennifer L., Toffaletti, Dena L., Giamberardino, Charles, Haverkamp, Miriam, Cuomo, Christina A., Perfect, John R.
Publicado 2021

Genotypic diversity and clinical outcome of cryptococcosis in renal transplant recipients in Brazil

por Ponzio, Vinicius, Chen, Yuan, Rodrigues, Anderson Messias, Tenor, Jennifer L., Toffaletti, Dena L., Medina-Pestana, José Osmar, Colombo, Arnaldo Lopes, Perfect, John R.
Publicado 2019

Pleiotropic Effects of Deubiquitinating Enzyme Ubp5 on Growth and Pathogenesis of Cryptococcus neoformans

por Fang, Wei, Price, Michael S., Toffaletti, Dena L., Tenor, Jennifer, Betancourt-Quiroz, Marisol, Price, Jennifer L., Pan, Wei-hua, Liao, Wan-qing, Perfect, John R.
Publicado 2012

Landscape of gene expression variation of natural isolates of Cryptococcus neoformans in response to biologically relevant stresses

por Yu, Chen-Hsin, Chen, Yuan, Desjardins, Christopher A., Tenor, Jennifer L., Toffaletti, Dena L., Giamberardino, Charles, Litvintseva, Anastasia, Perfect, John R., Cuomo, Christina A.
Publicado 2019

168. Efficacy of the Novel gwt1 Inhibitor APX2039 in a Rabbit Model of cryptococcus Meningitis

por Shaw, Karen J, Giamberardino, Charles D, Soltow, Quinlyn A, Tenor, Jennifer, Toffaletti, Dena, Boua, Jane-Valeriane, Marius, Choiselle, Palmucci, Julia R, Perfect, John R
Publicado 2020

Transcriptional Profiles Elucidate Differential Host Responses to Infection with Cryptococcus neoformans and Cryptococcus gattii

por Holcomb, Zachary E., Steinbrink, Julie M., Zaas, Aimee K., Betancourt, Marisol, Tenor, Jennifer L., Toffaletti, Dena L., Alspaugh, J. Andrew, Perfect, John R., McClain, Micah T.
Publicado 2022

The Cryptococcus neoformans Transcriptome at the Site of Human Meningitis

por Chen, Yuan, Toffaletti, Dena L., Tenor, Jennifer L., Litvintseva, Anastasia P., Fang, Charles, Mitchell, Thomas G., McDonald, Tami R., Nielsen, Kirsten, Boulware, David R., Bicanic, Tihana, Perfect, John R.
Publicado 2014

In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus

por Shaw, Karen Joy, Schell, Wiley A., Covel, Jonathan, Duboc, Gisele, Giamberardino, C., Kapoor, Mili, Moloney, Molly, Soltow, Quinlyn A., Tenor, Jennifer L., Toffaletti, Dena L., Trzoss, Michael, Webb, Peter, Perfect, John R.
Publicado 2018

Pharmacodynamics of ATI-2307 in a rabbit model of cryptococcal meningoencephalitis

por Giamberardino, Charles D., Tenor, Jennifer L., Toffaletti, Dena L., Palmucci, Julia R., Schell, Wiley, Boua, Jane-Valeriane K., Marius, Choiselle, Stott, Katharine E., Steele, Shelby L., Hope, William, Cilla, Don, Perfect, John R.
Publicado 2023

Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii

por Chen, Yuan, Farrer, Rhys A., Giamberardino, Charles, Sakthikumar, Sharadha, Jones, Alexander, Yang, Timothy, Tenor, Jennifer L., Wagih, Omar, Van Wyk, Marelize, Govender, Nelesh P., Mitchell, Thomas G., Litvintseva, Anastasia P., Cuomo, Christina A., Perfect, John R.
Publicado 2017

Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans

por So, Yee-Seul, Maeng, Shinae, Yang, Dong-Hoon, Kim, Hyelim, Lee, Kyung-Tae, Yu, Seong-Ryong, Tenor, Jennifer L., Giri, Vinay K., Toffaletti, Dena L., Arras, Samantha, Fraser, James A., Perfect, John R., Bahn, Yong-Sun
Publicado 2019

Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans

por Desjardins, Christopher A., Giamberardino, Charles, Sykes, Sean M., Yu, Chen-Hsin, Tenor, Jennifer L., Chen, Yuan, Yang, Timothy, Jones, Alexander M., Sun, Sheng, Haverkamp, Miriam R., Heitman, Joseph, Litvintseva, Anastasia P., Perfect, John R., Cuomo, Christina A.
Publicado 2017

Efficacy of APX2039 in a Rabbit Model of Cryptococcal Meningitis

por Giamberardino, Charles D., Schell, Wiley A., Tenor, Jennifer L., Toffaletti, Dena L., Palmucci, Julia R., Marius, Choiselle, Boua, Jane-Valeriane K., Soltow, Quinlyn, Mansbach, Robert, Moseley, M. Arthur, Thompson, J. Will, Dubois, Laura G., Hope, William, Perfect, John R., Shaw, Karen Joy
Publicado 2022

Assessing the virulence of Cryptococcus neoformans causing meningitis in HIV infected and uninfected patients in Vietnam

por Thanh, Lam Tuan, Toffaletti, Dena L, Tenor, Jennifer L, Giamberardino, Charles, Sempowski, Gregory D, Asfaw, Yohannes, Phan, Hai Trieu, Van Duong, Anh, Trinh, Nguyen Mai, Thwaites, Guy E, Ashton, Philip M, Chau, Nguyen Va Vinh, Baker, Stephen G, Perfect, John R, Day, Jeremy N
Publicado 2020

Comparison of Cryptococcus gattii/neoformans Species Complex to Related Genera (Papiliotrema and Naganishia) Reveal Variances in Virulence Associated Factors and Antifungal Suscept...

por Oliveira, Lana Sarita de Souza, Pinto, Luciana Magalhães, de Medeiros, Mariana Araújo Paulo, Toffaletti, Dena L., Tenor, Jennifer L., Barros, Tânia Fraga, Neves, Rejane Pereira, Neto, Reginaldo Gonçalves de Lima, Milan, Eveline Pipolo, Padovan, Ana Carolina Barbosa, Rocha, Walicyranison Plinio da Silva, Perfect, John R., Chaves, Guilherme Maranhão
Publicado 2021

Genomic Variation across a Clinical Cryptococcus Population Linked to Disease Outcome

por Sephton-Clark, Poppy, Tenor, Jennifer L., Toffaletti, Dena L., Meyers, Nancy, Giamberardino, Charles, Molloy, Síle F., Palmucci, Julia R., Chan, Adrienne, Chikaonda, Tarsizio, Heyderman, Robert, Hosseinipour, Mina, Kalata, Newton, Kanyama, Cecilia, Kukacha, Christopher, Lupiya, Duncan, Mwandumba, Henry C., Harrison, Thomas, Bicanic, Tihana, Perfect, John R., Cuomo, Christina A.
Publicado 2022