Snapshots of Pluripotency

por Tesar, Paul J.
Publicado 2016

Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay

por Martin, Sophie, Allan, Kevin C., Pinkard, Otis, Sweet, Thomas, Tesar, Paul J., Coller, Jeff
Publicado 2022

Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis

por Zechel, Jennifer L, Doerner, Stephanie K, Lager, Angela, Tesar, Paul J, Heaney, Jason D, Nadeau, Joseph H
Publicado 2013

Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease

por Foliaki, Simote T., Groveman, Bradley R., Yuan, Jue, Walters, Ryan, Zhang, Shulin, Tesar, Paul, Zou, Wenquan, Haigh, Cathryn L.
Publicado 2020

Lgr5 Marks Post-Mitotic, Lineage Restricted Cerebellar Granule Neurons during Postnatal Development

por Miller, Tyler E., Wang, Jun, Sukhdeo, Kumar, Horbinski, Craig, Tesar, Paul J., Wechsler-Reya, Robert J., Rich, Jeremy N.
Publicado 2014

Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells

por Najm, Fadi J., Zaremba, Anita, Caprariello, Andrew V., Nayak, Shreya, Freundt, Eric C., Scacheri, Peter C., Miller, Robert H., Tesar, Paul J.
Publicado 2011

Using iPSC‐derived human DA neurons from opioid‐dependent subjects to study dopamine dynamics

por Sheng, Yang, Filichia, Emily, Shick, Elizabeth, Preston, Kenzie L., Phillips, Karran A., Cooperman, Leslie, Lin, Zhicheng, Tesar, Paul, Hoffer, Barry, Luo, Yu
Publicado 2016

Pervasive environmental chemicals impair oligodendrocyte development

por Cohn, Erin F., Clayton, Benjamin L.L., Madhavan, Mayur, Yacoub, Sara, Federov, Yuriy, Paul-Friedman, Katie, Shafer, Timothy J., Tesar, Paul J.
Publicado 2023

The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming

por Boshans, Linda L., Factor, Daniel C., Singh, Vijender, Liu, Jia, Zhao, Chuntao, Mandoiu, Ion, Lu, Q. Richard, Casaccia, Patrizia, Tesar, Paul J., Nishiyama, Akiko
Publicado 2019

An ES-Like Pluripotent State in FGF-Dependent Murine iPS cells

por Di Stefano, Bruno, Buecker, Christa, Ungaro, Federica, Prigione, Alessandro, Chen, Hsu-Hsin, Welling, Maaike, Eijpe, Maureen, Mostoslavsky, Gustavo, Tesar, Paul, Adjaye, James, Geijsen, Niels, Broccoli, Vania
Publicado 2010

Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

por Najm, Fadi J., Lager, Angela M., Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V., Factor, Daniel C., Karl, Robert T., Maeda, Tadao, Miller, Robert H., Tesar, Paul J.
Publicado 2013

Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

por Lager, Angela M., Corradin, Olivia G., Cregg, Jared M., Elitt, Matthew S., Shick, H. Elizabeth, Clayton, Benjamin L. L., Allan, Kevin C., Olsen, Hannah E., Madhavan, Mayur, Tesar, Paul J.
Publicado 2018

Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis

por Clayton, Benjamin L.L., Barbar, Lilianne, Sapar, Maria, Rusielewicz, Tomasz, Kalpana, Kriti, Migliori, Bianca, Paull, Daniel, Brenner, Katie, Moroziewicz, Dorota, Sand, Ilana Katz, Casaccia, Patrizia, Tesar, Paul J., Fossati, Valentina
Publicado 2023

Inhibition of SC4MOL and HSD17B7 shifts cellular sterol composition and promotes oligodendrocyte formation

por Pleshinger, Matthew J, Friedrich, Ryan M., Hubler, Zita, Rivera-León, Adrianna M., Gao, Farrah, Yan, David, Sax, Joel L., Srinivasan, Ramya, Bederman, Ilya, Shick, H. Elizabeth, Tesar, Paul J., Adams, Drew J.
Publicado 2021

Enteric glial hub cells coordinate intestinal motility

por Scavuzzo, Marissa A., Letai, Katherine C., Maeno-Hikichi, Yuka, Wulftange, William J., Shah, Isha K., Rameshbabu, Jeyashri S., Tomar, Alka, Shick, H. Elizabeth, Shah, Aakash K., Xiong, Ying, Cohn, Erin F., Allan, Kevin C., Tesar, Paul J.
Publicado 2023

Identification and Characterization of Cell Type–Specific and Ubiquitous Chromatin Regulatory Structures in the Human Genome

por Xi, Hualin, Shulha, Hennady P, Lin, Jane M, Vales, Teresa R, Fu, Yutao, Bodine, David M, McKay, Ronald D. G, Chenoweth, Josh G, Tesar, Paul J, Furey, Terrence S, Ren, Bing, Weng, Zhiping, Crawford, Gregory E
Publicado 2007

CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression

por Schnetz, Michael P., Handoko, Lusy, Akhtar-Zaidi, Batool, Bartels, Cynthia F., Pereira, C. Filipe, Fisher, Amanda G., Adams, David J., Flicek, Paul, Crawford, Gregory E., LaFramboise, Thomas, Tesar, Paul, Wei, Chia-Lin, Scacheri, Peter C.
Publicado 2010

Induction of Myelinating Oligodendrocytes in Human Cortical Spheroids

por Madhavan, Mayur, Nevin, Zachary S., Shick, H. Elizabeth, Garrison, Eric, Clarkson-Paredes, Cheryl, Karl, Molly, Clayton, Benjamin L.L., Factor, Daniel C., Allan, Kevin C., Barbar, Lilianne, Jain, Tanya, Douvaras, Panagiotis, Fossati, Valentina, Miller, Robert H., Tesar, Paul J.
Publicado 2018

Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease

por Elitt, Matthew S., Shick, H. Elizabeth, Madhavan, Mayur, Allan, Kevin C., Clayton, Benjamin L.L., Weng, Chen, Miller, Tyler E., Factor, Daniel C., Barbar, Lilianne, Nawash, Baraa S., Nevin, Zachary S., Lager, Angela M., Li, Yan, Jin, Fulai, Adams, Drew J., Tesar, Paul J.
Publicado 2018

Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination

por Hubler, Zita, Allimuthu, Dharmaraja, Bederman, Ilya, Elitt, Matthew S., Madhavan, Mayur, Allan, Kevin C., Shick, H. Elizabeth, Garrison, Eric, Karl, Molly, Factor, Daniel C., Nevin, Zachary S., Sax, Joel L., Thompson, Matthew A., Fedorov, Yuriy, Jin, Jing, Wilson, William K., Giera, Martin, Bracher, Franz, Miller, Robert H., Tesar, Paul J., Adams, Drew J.
Publicado 2018