Nanobodies dismantle post‐pyroptotic ASC specks and counteract inflammation in vivo

por Bertheloot, Damien, Wanderley, Carlos WS, Schneider, Ayda H, Schiffelers, Lisa DJ, Wuerth, Jennifer D, Tödtmann, Jan MP, Maasewerd, Salie, Hawwari, Ibrahim, Duthie, Fraser, Rohland, Cornelia, Ribeiro, Lucas S, Jenster, Lea‐Marie, Rosero, Nathalia, Tesfamariam, Yonas M, Cunha, Fernando Q, Schmidt, Florian I, Franklin, Bernardo S
Publicado 2022

P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

por Jenster, Lea-Marie, Lange, Karl-Elmar, Normann, Sabine, vom Hemdt, Anja, Wuerth, Jennifer D., Schiffelers, Lisa D.J., Tesfamariam, Yonas M., Gohr, Florian N., Klein, Laura, Kaltheuner, Ines H., Ebner, Stefan, Lapp, Dorothee J., Mayer, Jacob, Moecking, Jonas, Ploegh, Hidde L., Latz, Eicke, Meissner, Felix, Geyer, Matthias, Kümmerer, Beate M., Schmidt, Florian I.
Publicado 2022

Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape

por Koenig, Paul-Albert, Das, Hrishikesh, Liu, Hejun, Kümmerer, Beate M., Gohr, Florian N., Jenster, Lea-Marie, Schiffelers, Lisa D. J., Tesfamariam, Yonas M., Uchima, Miki, Wuerth, Jennifer D., Gatterdam, Karl, Ruetalo, Natalia, Christensen, Maria H., Fandrey, Caroline I., Normann, Sabine, Tödtmann, Jan M. P., Pritzl, Steffen, Hanke, Leo, Boos, Jannik, Yuan, Meng, Zhu, Xueyong, Schmid-Burgk, Jonathan L., Kato, Hiroki, Schindler, Michael, Wilson, Ian A., Geyer, Matthias, Ludwig, Kerstin U., Hällberg, B. Martin, Wu, Nicholas C., Schmidt, Florian I.
Publicado 2021