A kinetic method for measuring agonist efficacy and ligand bias using high resolution biosensors and a kinetic data analysis framework

por Hoare, Sam R. J., Tewson, Paul H., Quinn, Anne Marie, Hughes, Thomas E.
Publicado 2020

N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP(2)

por Pratt, Emily B., Tewson, Paul, Bruederle, Cathrin E., Skach, William R., Shyng, Show-Ling
Publicado 2011

New DAG and cAMP Sensors Optimized for Live-Cell Assays in Automated Laboratories

por Tewson, Paul H., Martinka, Scott, Shaner, Nathan C., Hughes, Thomas E., Quinn, Anne Marie
Publicado 2015

Simultaneous Detection of Ca(2+) and Diacylglycerol Signaling in Living Cells

por Tewson, Paul, Westenberg, Mara, Zhao, Yongxin, Campbell, Robert E., Quinn, Anne Marie, Hughes, Thomas E.
Publicado 2012

Correction: Simultaneous Detection of Ca(2+) and Diacylglycerol Signaling in Living Cells

por Tewson, Paul, Westenberg, Mara, Zhao, Yongxin, Campbell, Robert E., Quinn, Anne Marie, Hughes, Thomas E.
Publicado 2014

Analyzing kinetic signaling data for G-protein-coupled receptors

por Hoare, Sam R. J., Tewson, Paul H., Quinn, Anne Marie, Hughes, Thomas E., Bridge, Lloyd J.
Publicado 2020

Quantifying the Kinetics of Signaling and Arrestin Recruitment by Nervous System G-Protein Coupled Receptors

por Hoare, Sam R. J., Tewson, Paul H., Sachdev, Shivani, Connor, Mark, Hughes, Thomas E., Quinn, Anne Marie
Publicado 2022

PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity

por Chen, Xingjuan, Egly, Christian, Riley, Ashley M., Li, Wennan, Tewson, Paul, Hughes, Thomas E., Quinn, Anne Marie, Obukhov, Alexander G.
Publicado 2014

Diazoxide-Unresponsive Congenital Hyperinsulinism in Children With Dominant Mutations of the β-Cell Sulfonylurea Receptor SUR1

por MacMullen, Courtney M., Zhou, Qing, Snider, Kara E., Tewson, Paul H., Becker, Susan A., Aziz, Ali Rahim, Ganguly, Arupa, Shyng, Show-Ling, Stanley, Charles A.
Publicado 2011

Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange

por Ding, Yidan, Li, Jiao, Enterina, Jhon Ralph, Shen, Yi, Zhang, Issan, Tewson, Paul H., Mo, Gary C. H., Zhang, Jin, Quinn, Anne Marie, Hughes, Thomas E., Maysinger, Dusica, Alford, Spencer C., Zhang, Yan, Campbell, Robert E.
Publicado 2015