Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization

por Dyer, Douglas P., Migliorini, Elisa, Salanga, Catherina L., Thakar, Dhruv, Handel, Tracy M., Richter, Ralf P.
Publicado 2017

Incorporation of Pentraxin 3 into Hyaluronan Matrices Is Tightly Regulated and Promotes Matrix Cross-linking

por Baranova, Natalia S., Inforzato, Antonio, Briggs, David C., Tilakaratna, Viranga, Enghild, Jan J., Thakar, Dhruv, Milner, Caroline M., Day, Anthony J., Richter, Ralf P.
Publicado 2014

Cytokines and growth factors cross-link heparan sulfate

por Migliorini, Elisa, Thakar, Dhruv, Kühnle, Jens, Sadir, Rabia, Dyer, Douglas P., Li, Yong, Sun, Changye, Volkman, Brian F., Handel, Tracy M., Coche-Guerente, Liliane, Fernig, David G., Lortat-Jacob, Hugues, Richter, Ralf P.
Publicado 2015

Intratumoral delivery of TransCon(™) TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction

por Zúñiga, Luis Alejandro, Leßmann, Torben, Uppal, Karan, Bisek, Nicola, Hong, Enping, Rasmussen, Caroline E., Karlsson, Jens-Jakob, Zettler, Joachim, Holten-Andersen, Lars, Bang, Kathy, Thakar, Dhruv, Lee, Yu-Chi, Martinez, Salomon, Sabharwal, Simran Singh, Stark, Sebastian, Faltinger, Frank, Kracker, Oliver, Weisbrod, Samuel, Müller, Robin, Voigt, Tobias, Bigott, Kornelia, Tabrizifard, Mohammad, Breinholt, Vibeke Miller, Mirza, Amer M., Rosen, David B., Sprogøe, Kennett, Punnonen, Juha
Publicado 2022

TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune...

por Rosen, David B, Kvarnhammar, Anne Månsson, Laufer, Burkhardt, Knappe, Thomas, Karlsson, Jens Jakob, Hong, Enping, Lee, Yu-Chi, Thakar, Dhruv, Zúñiga, Luis Alejandro, Bang, Kathy, Sabharwal, Simran Singh, Uppal, Karan, Olling, Janne Damm, Kjaergaard, Kristian, Kurpiers, Thomas, Schnabel, Meike, Reich, Diana, Glock, Philipp, Zettler, Joachim, Krusch, Mathias, Bernhard, Ana, Heinig, Stefan, Konjik, Valentino, Wegge, Thomas, Hehn, Yvonne, Killian, Steffen, Viet, Laura, Runz, Josefine, Faltinger, Frank, Tabrizi, Mohammad, Abel, Kristin Laura, Breinholt, Vibeke Miller, Singel, Stina M, Sprogøe, Kennett, Punnonen, Juha
Publicado 2022