The emerging determinants of replication fork stability

por Thakar, Tanay, Moldovan, George-Lucian
Publicado 2021

Base-editing screens illuminate variant effects in human hematopoiesis

por Vaitsiankova, Alina, Thakar, Tanay, Ciccia, Alberto
Publicado 2023

Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling

por Thakar, Tanay, Dhoonmoon, Ashna, Straka, Joshua, Schleicher, Emily M., Nicolae, Claudia M., Moldovan, George-Lucian
Publicado 2022

Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells

por Clements, Kristen E, Thakar, Tanay, Nicolae, Claudia M, Liang, Xinwen, Wang, Hong-Gang, Moldovan, George-Lucian
Publicado 2018

Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly

por Thakar, Tanay, Leung, Wendy, Nicolae, Claudia M., Clements, Kristen E., Shen, Binghui, Bielinsky, Anja-Katrin, Moldovan, George-Lucian
Publicado 2020

WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells

por Datta, Arindam, Biswas, Kajal, Sommers, Joshua A., Thompson, Haley, Awate, Sanket, Nicolae, Claudia M., Thakar, Tanay, Moldovan, George-Lucian, Shoemaker, Robert H., Sharan, Shyam K., Brosh, Robert M.
Publicado 2021

Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens

por Clements, Kristen E., Schleicher, Emily M., Thakar, Tanay, Hale, Anastasia, Dhoonmoon, Ashna, Tolman, Nathanial J., Sharma, Anchal, Liang, Xinwen, Imamura Kawasawa, Yuka, Nicolae, Claudia M., Wang, Hong-Gang, De, Subhajyoti, Moldovan, George-Lucian
Publicado 2020