The FDA’s Experience with Emerging Genomics Technologies—Past, Present, and Future

por Xu, Joshua, Thakkar, Shraddha, Gong, Binsheng, Tong, Weida
Publicado 2016

Development of Decision Forest Models for Prediction of Drug-Induced Liver Injury in Humans Using A Large Set of FDA-approved Drugs

por Hong, Huixiao, Thakkar, Shraddha, Chen, Minjun, Tong, Weida
Publicado 2017

Deep Learning on High-Throughput Transcriptomics to Predict Drug-Induced Liver Injury

por Li, Ting, Tong, Weida, Roberts, Ruth, Liu, Zhichao, Thakkar, Shraddha
Publicado 2020

DeepCarc: Deep Learning-Powered Carcinogenicity Prediction Using Model-Level Representation

por Li, Ting, Tong, Weida, Roberts, Ruth, Liu, Zhichao, Thakkar, Shraddha
Publicado 2021

Editorial: Emerging Technologies Powering Rare and Neglected Disease Diagnosis and Theraphy Development

por Liu, Zhichao, Hatim, Qais, Thakkar, Shraddha, Roberts, Ruth, Shi, Tieliu
Publicado 2022

Corrigendum: DeepCarc: Deep learning-powered carcinogenicity prediction using model-level representation

por Li, Ting, Tong, Weida, Roberts, Ruth, Liu, Zhichao, Thakkar, Shraddha
Publicado 2022

A Nanotechnology-Based Platform for Extending the Pharmacokinetic and Binding Properties of Anti-methamphetamine Antibody Fragments

por Nanaware-Kharade, Nisha, Thakkar, Shraddha, Gonzalez III, Guillermo A., Peterson, Eric C.
Publicado 2015

Comprehensive Assessments of RNA-seq by the SEQC Consortium: FDA-Led Efforts Advance Precision Medicine

por Xu, Joshua, Gong, Binsheng, Wu, Leihong, Thakkar, Shraddha, Hong, Huixiao, Tong, Weida
Publicado 2016

Adaptability of AI for safety evaluation in regulatory science: A case study of drug-induced liver injury

por Connor, Skylar, Li, Ting, Roberts, Ruth, Thakkar, Shraddha, Liu, Zhichao, Tong, Weida
Publicado 2022

Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering

por Thakkar, Shraddha, Nanaware-Kharade, Nisha, Celikel, Reha, Peterson, Eric C., Varughese, Kottayil I.
Publicado 2014

Proceedings of the 2015 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference

por Wren, Jonathan D, Thakkar, Shraddha, Homayouni, Ramin, Johann, Donald J, Dozmorov, Mikhail G
Publicado 2015

Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein

por Thakkar, Shraddha, Wang, Xianwei, Khaidakov, Magomed, Dai, Yao, Gokulan, Kuppan, Mehta, Jawahar L., Varughese, Kottayil I.
Publicado 2015

Proceedings of the 2016 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference

por Wren, Jonathan D., Toby, Inimary, Hong, Huxiao, Nanduri, Bindu, Kaundal, Rakesh, Dozmorov, Mikhail G., Thakkar, Shraddha
Publicado 2016

Proceedings of the 2017 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference

por Wren, Jonathan D., Dozmorov, Mikhail G., Toby, Inimary, Nanduri, Bindu, Homayouni, Ramin, Manda, Prashanti, Thakkar, Shraddha
Publicado 2017

Antioxidant Tocols as Radiation Countermeasures (Challenges to be Addressed to Use Tocols as Radiation Countermeasures in Humans)

por Nukala, Ujwani, Thakkar, Shraddha, Krager, Kimberly J., Breen, Philip J., Compadre, Cesar M., Aykin-Burns, Nukhet
Publicado 2018

Proceedings of the 2018 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) conference

por Wren, Jonathan D., Doerkson, Robert J., Toby, Inimary T., Nanduri, Bindu, Homayouni, Ramin, Manda, Prashanti, Thakkar, Shraddha
Publicado 2019

Linking Pharmacogenomic Information on Drug Safety and Efficacy with Ethnic Minority Populations

por Li, Dan, Xie, April Hui, Liu, Zhichao, Li, Dongying, Ning, Baitang, Thakkar, Shraddha, Tong, Weida, Xu, Joshua
Publicado 2020

466 Development of a novel tocotrienol analogue, tocoflexol, as a radiomitigator

por Shrimali, Shivangi, Singh, Awantika, Manian, Rajeshkumar, Thakkar, Shraddha, Jones, Darin E., Aykin-Burns, Nukhet, Breen, Philip, Compadre, Cesar M.
Publicado 2023

Scaling bioinformatics applications on HPC

por Mikailov, Mike, Luo, Fu-Jyh, Barkley, Stuart, Valleru, Lohit, Whitney, Stephen, Liu, Zhichao, Thakkar, Shraddha, Tong, Weida, Petrick, Nicholas
Publicado 2017

Study of serious adverse drug reactions using FDA-approved drug labeling and MedDRA

por Wu, Leihong, Ingle, Taylor, Liu, Zhichao, Zhao-Wong, Anna, Harris, Stephen, Thakkar, Shraddha, Zhou, Guangxu, Yang, Junshuang, Xu, Joshua, Mehta, Darshan, Ge, Weigong, Tong, Weida, Fang, Hong
Publicado 2019