Production of Recombinant Replication-defective Lentiviruses Bearing the SARS-CoV or SARS-CoV-2 Attachment Spike Glycoprotein and Their Application in Receptor Tropism and Neutrali...

por Thakur, Nazia, Gallo, Giulia, Elreafey, Ahmed M. E., Bailey, Dalan
Publicado 2021

BST2/Tetherin Overexpression Modulates Morbillivirus Glycoprotein Production to Inhibit Cell–Cell Fusion

por Kelly, James T., Human, Stacey, Alderman, Joseph, Jobe, Fatoumatta, Logan, Leanne, Rix, Thomas, Gonçalves-Carneiro, Daniel, Leung, Corwin, Thakur, Nazia, Birch, Jamie, Bailey, Dalan
Publicado 2019

Combinatorial F-G Immunogens as Nipah and Respiratory Syncytial Virus Vaccine Candidates

por Isaacs, Ariel, Cheung, Stacey T. M., Thakur, Nazia, Jaberolansar, Noushin, Young, Andrew, Modhiran, Naphak, Bailey, Dalan, Graham, Simon P., Young, Paul R., Chappell, Keith J., Watterson, Daniel
Publicado 2021

Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients

por Cantoni, Diego, Mayora-Neto, Martin, Thakur, Nazia, Elrefaey, Ahmed M. E., Newman, Joseph, Vishwanath, Sneha, Nadesalingam, Angalee, Chan, Andrew, Smith, Peter, Castillo-Olivares, Javier, Baxendale, Helen, Charleston, Bryan, Heeney, Jonathan, Bailey, Dalan, Temperton, Nigel
Publicado 2022

Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2

por Newman, Joseph, Thakur, Nazia, Peacock, Thomas P., Bialy, Dagmara, Elrefaey, Ahmed M. E., Bogaardt, Carlijn, Horton, Daniel L., Ho, Sammy, Kankeyan, Thivya, Carr, Christine, Hoschler, Katja, Barclay, Wendy S., Amirthalingam, Gayatri, Brown, Kevin E., Charleston, Bryan, Bailey, Dalan
Publicado 2022

Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion

por Thakur, Nazia, Conceicao, Carina, Isaacs, Ariel, Human, Stacey, Modhiran, Naphak, McLean, Rebecca K., Pedrera, Miriam, Tan, Tiong Kit, Rijal, Pramila, Townsend, Alain, Taylor, Geraldine, Young, Paul R., Watterson, Daniel, Chappell, Keith J., Graham, Simon P., Bailey, Dalan
Publicado 2020

Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs

por Pedrera, Miriam, Macchi, Francesca, McLean, Rebecca K., Franceschi, Valentina, Thakur, Nazia, Russo, Luca, Medfai, Lobna, Todd, Shawn, Tchilian, Elma Z., Audonnet, Jean-Christophe, Chappell, Keith, Isaacs, Ariel, Watterson, Daniel, Young, Paul R., Marsh, Glenn A., Bailey, Dalan, Graham, Simon P., Donofrio, Gaetano
Publicado 2020

Efficacy of ChAdOx1 vaccines against SARS-CoV-2 Variants of Concern Beta, Delta and Omicron in the Syrian hamster model

por van Doremalen, Neeltje, Schulz, Jonathan E., Adney, Danielle R., Saturday, Taylor A., Fischer, Robert J., Yinda, Claude Kwe, Thakur, Nazia, Newman, Joseph, Ulaszewska, Marta, Belij-Rammerstorfer, Sandra, Saturday, Greg, Spencer, Alexandra J., Bailey, Dalan, Gilbert, Sarah C., Lambe, Teresa, Munster, Vincent J.
Publicado 2022

Tfh cells and the germinal center are required for memory B cell formation & humoral immunity after ChAdOx1 nCoV-19 vaccination

por Foster, William S., Lee, Jia Le, Thakur, Nazia, Newman, Joseph, Spencer, Alexandra J., Davies, Sophie, Woods, Danielle, Godfrey, Leila, Hay, Iain M., Innocentin, Silvia, Yam-Puc, Juan Carlos, Horner, Emily C., Sharpe, Hayley J., Thaventhiran, James E., Bailey, Dalan, Lambe, Teresa, Linterman, Michelle A.
Publicado 2022

ChAdOx1 nCoV-19 (AZD1222) or nCoV-19-Beta (AZD2816) protect Syrian hamsters against Beta Delta and Omicron variants

por van Doremalen, Neeltje, Schulz, Jonathan E., Adney, Danielle R., Saturday, Taylor A., Fischer, Robert J., Yinda, Claude Kwe, Thakur, Nazia, Newman, Joseph, Ulaszewska, Marta, Belij-Rammerstorfer, Sandra, Saturday, Greg, Spencer, Alexandra J., Bailey, Dalan, Russell, Colin A., Gilbert, Sarah C., Lambe, Teresa, Munster, Vincent J.
Publicado 2022

An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity

por Wing, Peter A. C., Schmidt, Nathalie M., Peters, Rory, Erdmann, Maximilian, Brown, Rachel, Wang, Hao, Swadling, Leo, Newman, Joseph, Thakur, Nazia, Shionoya, Kaho, Morgan, Sophie B., Hinks, Timothy SC, Watashi, Koichi, Bailey, Dalan, Hansen, Scott B., Davidson, Andrew D., Maini, Mala K., McKeating, Jane A.
Publicado 2023

A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice

por Silva-Cayetano, Alyssa, Foster, William S., Innocentin, Silvia, Belij-Rammerstorfer, Sandra, Spencer, Alexandra J., Burton, Oliver T., Fra-Bidó, Sigrid, Le Lee, Jia, Thakur, Nazia, Conceicao, Carina, Wright, Daniel, Barrett, Jordan, Evans-Bailey, Nicola, Noble, Carly, Bailey, Dalan, Liston, Adrian, Gilbert, Sarah C., Lambe, Teresa, Linterman, Michelle A.
Publicado 2021

Differential susceptibility of SARS‐CoV‐2 in animals: Evidence of ACE2 host receptor distribution in companion animals, livestock and wildlife by immunohistochemical characterisati...

por Lean, Fabian Z. X., Núñez, Alejandro, Spiro, Simon, Priestnall, Simon L., Vreman, Sandra, Bailey, Dalan, James, Joe, Wrigglesworth, Ethan, Suarez‐Bonnet, Alejandro, Conceicao, Carina, Thakur, Nazia, Byrne, Alexander M.P., Ackroyd, Stuart, Delahay, Richard J., van der Poel, Wim H. M., Brown, Ian H., Fooks, Anthony R., Brookes, Sharon M.
Publicado 2021

The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins

por Conceicao, Carina, Thakur, Nazia, Human, Stacey, Kelly, James T., Logan, Leanne, Bialy, Dagmara, Bhat, Sushant, Stevenson-Leggett, Phoebe, Zagrajek, Adrian K., Hollinghurst, Philippa, Varga, Michal, Tsirigoti, Christina, Tully, Matthew, Chiu, Chris, Moffat, Katy, Silesian, Adrian Paul, Hammond, John A., Maier, Helena J., Bickerton, Erica, Shelton, Holly, Dietrich, Isabelle, Graham, Stephen C., Bailey, Dalan
Publicado 2020

Porcine Respiratory Coronavirus as a Model for Acute Respiratory Coronavirus Disease

por Keep, Sarah, Carr, Brigid Veronica, Lean, Fabian Z. X., Fones, Albert, Newman, Joseph, Dowgier, Giulia, Freimanis, Graham, Vatzia, Eleni, Polo, Noemi, Everest, Holly, Webb, Isobel, Mcnee, Adam, Paudyal, Basu, Thakur, Nazia, Nunez, Alejandro, MacLoughlin, Ronan, Maier, Helena, Hammond, John, Bailey, Dalan, Waters, Ryan, Charleston, Bryan, Tuthill, Toby, Britton, Paul, Bickerton, Erica, Tchilian, Elma
Publicado 2022

The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 beta (B.1.351) and other variants of concern in preclinical studies

por Spencer, Alexandra J, Morris, Susan, Ulaszewska, Marta, Powers, Claire, Kailath, Reshma, Bissett, Cameron, Truby, Adam, Thakur, Nazia, Newman, Joseph, Allen, Elizabeth R, Rudiansyah, Indra, Liu, Chang, Dejnirattisai, Wanwisa, Mongkolsapaya, Juthathip, Davies, Hannah, Donnellan, Francesca R, Pulido, David, Peacock, Thomas P., Barclay, Wendy S., Bright, Helen, Ren, Kuishu, Screaton, Gavin, McTamney, Patrick, Bailey, Dalan, Gilbert, Sarah C, Lambe, Teresa
Publicado 2022

A platform technology for generating subunit vaccines against diverse viral pathogens

por Young, Andrew, Isaacs, Ariel, Scott, Connor A. P., Modhiran, Naphak, McMillan, Christopher L. D., Cheung, Stacey T. M., Barr, Jennifer, Marsh, Glenn, Thakur, Nazia, Bailey, Dalan, Li, Kenneth S. M., Luk, Hayes K. H., Kok, Kin-Hang, Lau, Susanna K. P., Woo, Patrick C. Y., Furuyama, Wakako, Marzi, Andrea, Young, Paul R., Chappell, Keith J., Watterson, Daniel
Publicado 2022

Genomic screening of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential

por Tan, Cedric C. S., Trew, Jahcub, Peacock, Thomas P., Mok, Kai Yi, Hart, Charlie, Lau, Kelvin, Ni, Dongchun, Orme, C. David L., Ransome, Emma, Pearse, William D., Coleman, Christopher M., Bailey, Dalan, Thakur, Nazia, Quantrill, Jessica L., Sukhova, Ksenia, Richard, Damien, Kahane, Laura, Woodward, Guy, Bell, Thomas, Worledge, Lisa, Nunez-Mino, Joe, Barclay, Wendy, van Dorp, Lucy, Balloux, Francois, Savolainen, Vincent
Publicado 2023

Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

por Meng, Bo, Kemp, Steven A., Papa, Guido, Datir, Rawlings, Ferreira, Isabella A.T.M., Marelli, Sara, Harvey, William T., Lytras, Spyros, Mohamed, Ahmed, Gallo, Giulia, Thakur, Nazia, Collier, Dami A., Mlcochova, Petra, Duncan, Lidia M., Carabelli, Alessandro M., Kenyon, Julia C., Lever, Andrew M., De Marco, Anna, Saliba, Christian, Culap, Katja, Cameroni, Elisabetta, Matheson, Nicholas J., Piccoli, Luca, Corti, Davide, James, Leo C., Robertson, David L., Bailey, Dalan, Gupta, Ravindra K.
Publicado 2021

The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

por Zhuang, Xiaodong, Tsukuda, Senko, Wrensch, Florian, Wing, Peter A.C., Schilling, Mirjam, Harris, James M., Borrmann, Helene, Morgan, Sophie B., Cane, Jennifer L., Mailly, Laurent, Thakur, Nazia, Conceicao, Carina, Sanghani, Harshmeena, Heydmann, Laura, Bach, Charlotte, Ashton, Anna, Walsh, Steven, Tan, Tiong Kit, Schimanski, Lisa, Huang, Kuan-Ying A., Schuster, Catherine, Watashi, Koichi, Hinks, Timothy S.C., Jagannath, Aarti, Vausdevan, Sridhar R., Bailey, Dalan, Baumert, Thomas F., McKeating, Jane A.
Publicado 2021