Midlife anticholinergic drug use, risk of Alzheimer's disease, and brain atrophy in community-dwelling older adults

por Chuang, Yi-Fang, Elango, Palchamy, Gonzalez, Christopher E., Thambisetty, Madhav
Publicado 2017

Obesity and Longer Term Risks of Dementia in 65–74 Year Olds

por Bowman, Kirsty, Thambisetty, Madhav, Kuchel, George A, Ferrucci, Luigi, Melzer, David
Publicado 2019

Genetic Variation in Targets of Antidiabetic Drugs and Alzheimer Disease Risk: A Mendelian Randomization Study

por Tang, Bowen, Wang, Yunzhang, Jiang, Xia, Thambisetty, Madhav, Ferrucci, Luigi, Johnell, Kristina, Hägg, Sara
Publicado 2022

Metabolomic Method: UPLC-q-ToF Polar and Non-Polar Metabolites in the Healthy Rat Cerebellum Using an In-Vial Dual Extraction

por Ebshiana, Amera A., Snowden, Stuart G., Thambisetty, Madhav, Parsons, Richard, Hye, Abdul, Legido-Quigley, Cristina
Publicado 2015

A Decade of Blood Biomarkers for Alzheimer’s Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication

por Shi, Liu, Baird, Alison L., Westwood, Sarah, Hye, Abdul, Dobson, Richard, Thambisetty, Madhav, Lovestone, Simon
Publicado 2018

Bile Acids in Dementia: Brain Amyloid, White Matter Lesions, and Atrophy

por Varma, Vijay, Wang, Youjin, An, Yang, Varma, Sudhir, Bilgel, Murat, Doshi, Jimit, Legido-Quigley, Cristina, Thambisetty, Madhav
Publicado 2020

Unbiased proteomics and multivariable regularized regression techniques identify SMOC1, NOG, APCS, and NTN1 in an Alzheimer’s disease brain proteomic signature

por Roberts, Jackson A., Varma, Vijay R., Candia, Julián, Tanaka, Toshiko, Ferrucci, Luigi, Bennett, David A., Thambisetty, Madhav
Publicado 2023

Systematic Identification of circRNAs in Alzheimer’s Disease

por Cochran, Kyle R., Veeraraghavan, Kirtana, Kundu, Gautam, Mazan-Mamczarz, Krystyna, Coletta, Christopher, Thambisetty, Madhav, Gorospe, Myriam, De, Supriyo
Publicado 2021

Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study

por Snowden, Stuart G., Ebshiana, Amera A., Hye, Abdul, An, Yang, Pletnikova, Olga, O’Brien, Richard, Troncoso, John, Legido-Quigley, Cristina, Thambisetty, Madhav
Publicado 2017

Comparative Risk of Alzheimer Disease and Related Dementia Among Medicare Beneficiaries With Rheumatoid Arthritis Treated With Targeted Disease-Modifying Antirheumatic Agents

por Desai, Rishi J., Varma, Vijay R., Gerhard, Tobias, Segal, Jodi, Mahesri, Mufaddal, Chin, Kristyn, Horton, Daniel B., Kim, Seoyoung C., Schneeweiss, Sebastian, Thambisetty, Madhav
Publicado 2022

FTO Genotype and Aging: Pleiotropic Longitudinal Effects on Adiposity, Brain function, Impulsivity and Diet

por Chuang, Yi-Fang, Tanaka, Toshiko, Beason-Held, Lori L., An, Yang, Terracciano, Antonio, Sutin, Angelina R., Kraut, Michael, Singleton, Andrew B., Resnick, Susan M., Thambisetty, Madhav
Publicado 2014

Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

por Johnson, Erik C. B., Dammer, Eric B., Duong, Duc M., Yin, Luming, Thambisetty, Madhav, Troncoso, Juan C., Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Publicado 2018

Blood Metabolite Signatures of Metabolic Syndrome in Two Cross-Cultural Older Adult Cohorts

por Mahajan, Uma V., Varma, Vijay R., Huang, Chiung-Wei, An, Yang, Tanaka, Toshiko, Ferrucci, Luigi, Takebayashi, Toru, Harada, Sei, Iida, Miho, Legido-Quigley, Cristina, Thambisetty, Madhav
Publicado 2020

Longitudinal associations between use of antihypertensive, antidiabetic, and lipid-lowering medications and biological aging

por Tang, Bowen, Li, Xia, Wang, Yunzhang, Sjölander, Arvid, Johnell, Kristina, Thambisetty, Madhav, Ferrucci, Luigi, Reynolds, Chandra A., Finkel, Deborah, Jylhävä, Juulia, Pedersen, Nancy L., Hägg, Sara
Publicado 2023

Blood Metabolite Signature of Metabolic Syndrome Implicates Alterations in Amino Acid Metabolism: Findings from the Baltimore Longitudinal Study of Aging (BLSA) and the Tsuruoka Me...

por Roberts, Jackson A., Varma, Vijay R., Huang, Chiung-Wei, An, Yang, Oommen, Anup, Tanaka, Toshiko, Ferrucci, Luigi, Elango, Palchamy, Takebayashi, Toru, Harada, Sei, Iida, Miho, Thambisetty, Madhav
Publicado 2020

Plasma proteomic signatures predict dementia and cognitive impairment

por Tanaka, Toshiko, Lavery, Robert, Varma, Vijay, Fantoni, Giovanna, Colpo, Marco, Thambisetty, Madhav, Candia, Julian, Resnick, Susan M., Bennett, David A., Biancotto, Angelique, Bandinelli, Stefania, Ferrucci, Luigi
Publicado 2020

A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer’s Disease

por Khan, Wasim, Aguilar, Carlos, Kiddle, Steven J., Doyle, Orla, Thambisetty, Madhav, Muehlboeck, Sebastian, Sattlecker, Martina, Newhouse, Stephen, Lovestone, Simon, Dobson, Richard, Giampietro, Vincent, Westman, Eric, Simmons, Andrew
Publicado 2015

U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer’s disease due to autosomal dominant genetic mutations and trisomy 21

por Hales, Chadwick M, Seyfried, Nicholas T, Dammer, Eric B, Duong, Duc, Yi, Hong, Gearing, Marla, Troncoso, Juan C, Mufson, Elliott J, Thambisetty, Madhav, Levey, Allan I, Lah, James J
Publicado 2014

Acid ceramidase promotes senescent cell survival

por Munk, Rachel, Anerillas, Carlos, Rossi, Martina, Tsitsipatis, Dimitrios, Martindale, Jennifer L., Herman, Allison B., Yang, Jen-Hao, Roberts, Jackson A., Varma, Vijay R., Pandey, Poonam R., Thambisetty, Madhav, Gorospe, Myriam, Abdelmohsen, Kotb
Publicado 2021

Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study

por Mahajan, Uma V., Varma, Vijay R., Griswold, Michael E., Blackshear, Chad T., An, Yang, Oommen, Anup M., Varma, Sudhir, Troncoso, Juan C., Pletnikova, Olga, O’Brien, Richard, Hohman, Timothy J., Legido-Quigley, Cristina, Thambisetty, Madhav
Publicado 2020