Combinatorial genetics methods for discovering high-order regulatory combinations and engineering genetic drivers for neural differentiation

por Thean, Dawn G. L., Wong, Alan S. L.
Publicado 2021

Machine learning-coupled combinatorial mutagenesis enables resource-efficient engineering of CRISPR-Cas9 genome editor activities

por Thean, Dawn G. L., Chu, Hoi Yee, Fong, John H. C., Chan, Becky K. C., Zhou, Peng, Kwok, Cynthia C. S., Chan, Yee Man, Mak, Silvia Y. L., Choi, Gigi C. G., Ho, Joshua W. K., Zheng, Zongli, Wong, Alan S. L.
Publicado 2022

High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination

por Yuen, Chaya T L, Thean, Dawn G L, Chan, Becky K C, Zhou, Peng, Kwok, Cynthia C S, Chu, Hoi Yee, Cheung, Maggie S H, Wang, Bei, Chan, Yee Man, Mak, Silvia Y L, Leung, Anskar Y, Choi, Gigi C G, Zheng, Zongli, Wong, Alan S L
Publicado 2022