Turnip yellow mosaic virus protease binds ubiquitin suboptimally to fine-tune its deubiquitinase activity

por Fieulaine, Sonia, Witte, Martin D., Theile, Christopher S., Ayach, Maya, Ploegh, Hidde L., Jupin, Isabelle, Bressanelli, Stéphane
Publicado 2020

siRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2

por Elkayam, Elad, Parmar, Rubina, Brown, Christopher R., Willoughby, Jennifer L., Theile, Christopher S., Manoharan, Muthiah, Joshua-Tor, Leemor
Publicado 2017

siRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2

por Elkayam, Elad, Parmar, Rubina, Brown, Christopher R., Willoughby, Jennifer L., Theile, Christopher S., Manoharan, Muthiah, Joshua-Tor, Leemor
Publicado 2017

Site-Specific Chemoenzymatic Labeling of Aerolysin Enables the Identification of New Aerolysin Receptors

por Wuethrich, Irene, Peeters, Janneke G. C., Blom, Annet E. M., Theile, Christopher S., Li, Zeyang, Spooner, Eric, Ploegh, Hidde L., Guimaraes, Carla P.
Publicado 2014

Generation and validation of structurally defined antibody–siRNA conjugates

por Nanna, Alex R, Kel’in, Alexander V, Theile, Christopher, Pierson, Justin M, Voo, Zhi Xiang, Garg, Ashish, Nair, Jayaprakash K, Maier, Martin A, Fitzgerald, Kevin, Rader, Christoph
Publicado 2020

Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells

por Avalos, Ana M., Bilate, Angelina M., Witte, Martin D., Tai, Albert K., He, Jiang, Frushicheva, Maria P., Thill, Peter D., Meyer-Wentrup, Friederike, Theile, Christopher S., Chakraborty, Arup K., Zhuang, Xiaowei, Ploegh, Hidde L.
Publicado 2014

Centyrin ligands for extrahepatic delivery of siRNA

por Klein, Donna, Goldberg, Shalom, Theile, Christopher S., Dambra, Richard, Haskell, Kathleen, Kuhar, Elise, Lin, Tricia, Parmar, Rubina, Manoharan, Muthiah, Richter, Mark, Wu, Meizhen, Mendrola Zarazowski, Jeannine, Jadhav, Vasant, Maier, Martin A., Sepp-Lorenzino, Laura, O’Neil, Karyn, Dudkin, Vadim
Publicado 2021

Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates

por Brown, Christopher R, Gupta, Swati, Qin, June, Racie, Timothy, He, Guo, Lentini, Scott, Malone, Ryan, Yu, Mikyung, Matsuda, Shigeo, Shulga-Morskaya, Svetlana, Nair, Anil V, Theile, Christopher S, Schmidt, Karyn, Shahraz, Azar, Goel, Varun, Parmar, Rubina G, Zlatev, Ivan, Schlegel, Mark K, Nair, Jayaprakash K, Jayaraman, Muthusamy, Manoharan, Muthiah, Brown, Dennis, Maier, Martin A, Jadhav, Vasant
Publicado 2020