Editorial: Advances in Human Immune System Mouse Models for Studying Human Hematopoiesis and Cancer Immunotherapy

por Saito, Yasuyuki, Willinger, Tim, Theocharides, Alexandre P. A.
Publicado 2021

Transient paraproteinemia after allogeneic hematopoietic stem cell transplantation is an underexplored phenomenon associated with graft versus host disease

por Widmer, Corinne C., Balabanov, Stefan, Schanz, Urs, Theocharides, Alexandre P.A.
Publicado 2017

Candida albicans-Induced NETosis Is Independent of Peptidylarginine Deiminase 4

por Guiducci, Eva, Lemberg, Christina, Küng, Noëmi, Schraner, Elisabeth, Theocharides, Alexandre P. A., LeibundGut-Landmann, Salomé
Publicado 2018

Sensitive Quantitative Proteomics of Human Hematopoietic Stem and Progenitor Cells by Data-independent Acquisition Mass Spectrometry

por Amon, Sabine, Meier-Abt, Fabienne, Gillet, Ludovic C., Dimitrieva, Slavica, Theocharides, Alexandre P. A., Manz, Markus G., Aebersold, Ruedi
Publicado 2019

Reduced CXCL4/PF4 expression as a driver of increased human hematopoietic stem and progenitor cell proliferation in polycythemia vera

por Meier-Abt, Fabienne, Wolski, Witold E., Tan, Ge, Kummer, Sandra, Amon, Sabine, Manz, Markus G., Aebersold, Ruedi, Theocharides, Alexandre P. A.
Publicado 2021

Proteomic identification of proliferation and progression markers in human polycythemia vera stem and progenitor cells

por Tan, Ge, Wolski, Witold E., Kummer, Sandra, Hofstetter, Mara, Theocharides, Alexandre P. A., Manz, Markus G., Aebersold, Ruedi, Meier-Abt, Fabienne
Publicado 2022

The IL‐6 signaling complex is a critical driver, negative prognostic factor, and therapeutic target in diffuse large B‐cell lymphoma

por Hashwah, Hind, Bertram, Katrin, Stirm, Kristin, Stelling, Anna, Wu, Cheuk‐Ting, Kasser, Sabrina, Manz, Markus G, Theocharides, Alexandre P, Tzankov, Alexandar, Müller, Anne
Publicado 2019

Blocking the CD47-SIRPα interaction reverses the disease phenotype in a polycythemia vera mouse model

por Lysenko, Veronika, Schürch, Patrick M., Tuzlak, Selma, van Wijk, Nicole Wildner-Verhey, Kovtonyuk, Larisa V., Becher, Burkhard, Manz, Markus G., Kreutmair, Stefanie, Theocharides, Alexandre P. A.
Publicado 2023

PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy

por Maru, Bruktawit, Messikommer, Alessandra, Huang, Linhui, Seipel, Katja, Kovecses, Olivia, Valk, Peter J.M., Theocharides, Alexandre P.A., Mercier, Francois E., Pabst, Thomas, McKeague, Maureen, Luedtke, Nathan W.
Publicado 2023

Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria

por Halloy, François, Iyer, Pavithra S, Ćwiek, Paulina, Ghidini, Alice, Barman-Aksözen, Jasmin, Wildner-Verhey van Wijk, Nicole, Theocharides, Alexandre P A, Minder, Elisabeth I, Schneider-Yin, Xiaoye, Schümperli, Daniel, Hall, Jonathan
Publicado 2020

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts

por Theocharides, Alexandre P.A., Jin, Liqing, Cheng, Po-Yan, Prasolava, Tatiana K., Malko, Andrei V., Ho, Jenny M., Poeppl, Armando G., van Rooijen, Nico, Minden, Mark D., Danska, Jayne S., Dick, John E., Wang, Jean C.Y.
Publicado 2012

Proteogenetic drug response profiling elucidates targetable vulnerabilities of myelofibrosis

por Wildschut, Mattheus H. E., Mena, Julien, Dördelmann, Cyril, van Oostrum, Marc, Hale, Benjamin D., Settelmeier, Jens, Festl, Yasmin, Lysenko, Veronika, Schürch, Patrick M., Ring, Alexander, Severin, Yannik, Bader, Michael S., Pedrioli, Patrick G. A., Goetze, Sandra, van Drogen, Audrey, Balabanov, Stefan, Skoda, Radek C., Lopes, Massimo, Wollscheid, Bernd, Theocharides, Alexandre P. A., Snijder, Berend
Publicado 2023

Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms

por Grockowiak, Elodie, Korn, Claudia, Rak, Justyna, Lysenko, Veronika, Hallou, Adrien, Panvini, Francesca M., Williams, Matthew, Fielding, Claire, Fang, Zijian, Khatib-Massalha, Eman, García-García, Andrés, Li, Juan, Khorshed, Reema A., González-Antón, Sara, Baxter, E. Joanna, Kusumbe, Anjali, Wilkins, Bridget S., Green, Anna, Simons, Benjamin D., Harrison, Claire N., Green, Anthony R., Lo Celso, Cristina, Theocharides, Alexandre P. A., Méndez-Ferrer, Simón
Publicado 2023

An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein

por Kara, Eleanna, Crimi, Alessandro, Wiedmer, Anne, Emmenegger, Marc, Manzoni, Claudia, Bandres-Ciga, Sara, D’Sa, Karishma, Reynolds, Regina H., Botía, Juan A., Losa, Marco, Lysenko, Veronika, Carta, Manfredi, Heinzer, Daniel, Avar, Merve, Chincisan, Andra, Blauwendraat, Cornelis, García-Ruiz, Sonia, Pease, Daniel, Mottier, Lorene, Carrella, Alessandra, Beck-Schneider, Dezirae, Magalhães, Andreia D., Aemisegger, Caroline, Theocharides, Alexandre P.A., Fan, Zhanyun, Marks, Jordan D., Hopp, Sarah C., Abramov, Andrey Y., Lewis, Patrick A., Ryten, Mina, Hardy, John, Hyman, Bradley T., Aguzzi, Adriano
Publicado 2021