Beyond Structure: Defining the Function of the Gut Using Omic Approaches for Rational Design of Personalized Therapeutics

por Theriot, Casey M.
Publicado 2018

Diversification of host bile acids by members of the gut microbiota

por Winston, Jenessa A., Theriot, Casey M.
Publicado 2019

Contribution of Inhibitory Metabolites and Competition for Nutrients to Colonization Resistance against Clostridioides difficile by Commensal Clostridium

por Reed, Amber D., Theriot, Casey M.
Publicado 2021

Probiotic colonization dynamics after oral consumption of VSL#3(®) by antibiotic-treated mice

por Theriot, Casey, Thanissery, Rajani, O'Flaherty, Sarah, Barrangou, Rodolphe
Publicado 2022

Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine

por Theriot, Casey M., Bowman, Alison A., Young, Vincent B.
Publicado 2016

Shifts in the Gut Metabolome and Clostridium difficile Transcriptome throughout Colonization and Infection in a Mouse Model

por Fletcher, Joshua R., Erwin, Samantha, Lanzas, Cristina, Theriot, Casey M.
Publicado 2018

A Small Molecule-Screening Pipeline to Evaluate the Therapeutic Potential of 2-Aminoimidazole Molecules Against Clostridium difficile

por Thanissery, Rajani, Zeng, Daina, Doyle, Raul G., Theriot, Casey M.
Publicado 2018

Improving the Catalytic Activity of Hyperthermophilic Pyrococcus horikoshii Prolidase for Detoxification of Organophosphorus Nerve Agents over a Broad Range of Temperatures

por Theriot, Casey M., Semcer, Rebecca L., Shah, Saumil S., Grunden, Amy M.
Publicado 2011

The Lactobacillus Bile Salt Hydrolase Repertoire Reveals Niche-Specific Adaptation

por O’Flaherty, Sarah, Briner Crawley, Alexandra, Theriot, Casey M., Barrangou, Rodolphe
Publicado 2018

Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract

por Foley, Matthew H., O’Flaherty, Sarah, Barrangou, Rodolphe, Theriot, Casey M.
Publicado 2019

Tauroursodeoxycholic Acid Inhibits Clostridioides difficile Toxin-Induced Apoptosis

por Pike, Colleen M., Tam, John, Melnyk, Roman A., Theriot, Casey M.
Publicado 2022

Loss of Bacteroides thetaiotaomicron bile acid altering enzymes impact bacterial fitness and the global metabolic transcriptome

por McMillan, Arthur S., Foley, Matthew H., Perkins, Caroline E., Theriot, Casey M.
Publicado 2023

The Complete Campylobacter jejuni Transcriptome during Colonization of a Natural Host Determined by RNAseq

por Taveirne, Michael E., Theriot, Casey M., Livny, Jonathan, DiRita, Victor J.
Publicado 2013

Prolonged oral antimicrobial administration prevents doxorubicin-induced loss of active intestinal stem cells

por Sheahan, Breanna J, Theriot, Casey M, Cortes, Jocsa E., Dekaney, Christopher M
Publicado 2022

Secondary bile acid ursodeoxycholic acid alters weight, the gut microbiota, and the bile acid pool in conventional mice

por Winston, Jenessa A., Rivera, Alissa, Cai, Jingwei, Patterson, Andrew D., Theriot, Casey M.
Publicado 2021

The microbial derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota

por Kisthardt, Samantha C, Thanissery, Rajani, Pike, Colleen M, Foley, Matthew H, Theriot, Casey M
Publicado 2023

Complete Genome Sequence of Lactobacillus johnsonii NCK2677, Isolated from Mice

por O'Flaherty, Sarah, Foley, Matthew H., Rivera, Alissa J., Theriot, Casey M., Barrangou, Rodolphe
Publicado 2020

Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis

por Icho, Simoun, Ward, Jennifer S., Tam, John, Kociolek, Larry K., Theriot, Casey M., Melnyk, Roman A.
Publicado 2023

Lactobacillus bile salt hydrolase substrate specificity governs bacterial fitness and host colonization

por Foley, Matthew H., O’Flaherty, Sarah, Allen, Garrison, Rivera, Alissa J., Stewart, Allison K., Barrangou, Rodolphe, Theriot, Casey M.
Publicado 2021

Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation

por Noecker, Cecilia, Eng, Alexander, Srinivasan, Sujatha, Theriot, Casey M., Young, Vincent B., Jansson, Janet K., Fredricks, David N., Borenstein, Elhanan
Publicado 2016