Modeling X-chromosome inactivation and reactivation during human development

por Khan, Shafqat A, Theunissen, Thorold W
Publicado 2023

Accessing the human trophoblast stem cell state from pluripotent and somatic cells

por Karvas, Rowan M., David, Laurent, Theunissen, Thorold W.
Publicado 2022

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

por Silva, Jose, Barrandon, Ornella, Nichols, Jennifer, Kawaguchi, Jitsutaro, Theunissen, Thorold W, Smith, Austin
Publicado 2008

ZMYM2 inhibits NANOG-mediated reprogramming

por Lawrence, Moyra, Theunissen, Thorold W., Lombard, Patrick, Adams, David J., Silva, José C. R.
Publicado 2019

Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency

por Yang, Jian, van Oosten, Anouk L., Theunissen, Thorold W., Guo, Ge, Silva, Jose C.R., Smith, Austin
Publicado 2010

Nanog Overcomes Reprogramming Barriers and Induces Pluripotency in Minimal Conditions

por Theunissen, Thorold W., van Oosten, Anouk L., Castelo-Branco, Gonçalo, Hall, John, Smith, Austin, Silva, José C.R.
Publicado 2011

Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

por Pontis, Julien, Planet, Evarist, Offner, Sandra, Turelli, Priscilla, Duc, Julien, Coudray, Alexandre, Theunissen, Thorold W., Jaenisch, Rudolf, Trono, Didier
Publicado 2019

Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain

por Theunissen, Thorold W., Costa, Yael, Radzisheuskaya, Aliaksandra, van Oosten, Anouk L., Lavial, Fabrice, Pain, Bertrand, Castro, L. Filipe C., Silva, José C. R.
Publicado 2011

Nanog Is the Gateway to the Pluripotent Ground State

por Silva, Jose, Nichols, Jennifer, Theunissen, Thorold W., Guo, Ge, van Oosten, Anouk L., Barrandon, Ornella, Wray, Jason, Yamanaka, Shinya, Chambers, Ian, Smith, Austin
Publicado 2009

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

por Cheng, Albert W, Wang, Haoyi, Yang, Hui, Shi, Linyu, Katz, Yarden, Theunissen, Thorold W, Rangarajan, Sudharshan, Shivalila, Chikdu S, Dadon, Daniel B, Jaenisch, Rudolf
Publicado 2013

Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening

por Khan, Shafqat A., Park, Kyoung-mi, Fischer, Laura A., Dong, Chen, Lungjangwa, Tenzin, Jimenez, Marta, Casalena, Dominick, Chew, Brian, Dietmann, Sabine, Auld, Douglas S., Jaenisch, Rudolf, Theunissen, Thorold W.
Publicado 2021

A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells

por Dong, Chen, Fu, Shuhua, Karvas, Rowan M., Chew, Brian, Fischer, Laura A., Xing, Xiaoyun, Harrison, Jessica K., Popli, Pooja, Kommagani, Ramakrishna, Wang, Ting, Zhang, Bo, Theunissen, Thorold W.
Publicado 2022

Derivation of trophoblast stem cells from naïve human pluripotent stem cells

por Dong, Chen, Beltcheva, Mariana, Gontarz, Paul, Zhang, Bo, Popli, Pooja, Fischer, Laura A, Khan, Shafqat A, Park, Kyoung-mi, Yoon, Eun-Ja, Xing, Xiaoyun, Kommagani, Ramakrishna, Wang, Ting, Solnica-Krezel, Lilianna, Theunissen, Thorold W
Publicado 2020

Nanog-dependent function of Tet1 and Tet2 in establishment of pluripotency

por Costa, Yael, Ding, Junjun, Theunissen, Thorold W., Faiola, Francesco, Hore, Timothy A., Shliaha, Pavel V., Fidalgo, Miguel, Saunders, Arven, Lawrence, Moyra, Dietmann, Sabine, Das, Satyabrata, Levasseur, Dana N., Li, Zhe, Xu, Mingjiang, Reik, Wolf, Silva, José C.R., Wang, Jianlong
Publicado 2013

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

por Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Publicado 2014

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

por Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Publicado 2014

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

por Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Publicado 2014

Molecular Criteria for Defining the Naive Human Pluripotent State

por Theunissen, Thorold W., Friedli, Marc, He, Yupeng, Planet, Evarist, O’Neil, Ryan C., Markoulaki, Styliani, Pontis, Julien, Wang, Haoyi, Iouranova, Alexandra, Imbeault, Michaël, Duc, Julien, Cohen, Malkiel A., Wert, Katherine J., Castanon, Rosa, Zhang, Zhuzhu, Huang, Yanmei, Nery, Joseph R., Drotar, Jesse, Lungjangwa, Tenzin, Trono, Didier, Ecker, Joseph R., Jaenisch, Rudolf
Publicado 2016

OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human

por Huang, Xin, Park, Kyoung-mi, Gontarz, Paul, Zhang, Bo, Pan, Joshua, McKenzie, Zachary, Fischer, Laura A., Dong, Chen, Dietmann, Sabine, Xing, Xiaoyun, Shliaha, Pavel V., Yang, Jihong, Li, Dan, Ding, Junjun, Lungjangwa, Tenzin, Mitalipova, Maya, Khan, Shafqat A., Imsoonthornruksa, Sumeth, Jensen, Nick, Wang, Ting, Kadoch, Cigall, Jaenisch, Rudolf, Wang, Jianlong, Theunissen, Thorold W.
Publicado 2021