Membrane Lipids in Epithelial Polarity: Sorting out the PIPs

por Bugda Gwilt, Katlynn, Thiagarajah, Jay R.
Publicado 2022

Convective washout reduces the antidiarrheal efficacy of enterocyte surface–targeted antisecretory drugs

por Jin, Byung-Ju, Thiagarajah, Jay R., Verkman, A.S.
Publicado 2013

Response to “Diffusion versus convection”

por Jin, Byung-Ju, Thiagarajah, Jay R., Verkman, A.S.
Publicado 2013

The genetics of monogenic intestinal epithelial disorders

por Babcock, Stephen J., Flores-Marin, David, Thiagarajah, Jay R.
Publicado 2022

Airway surface liquid depth imaged by surface laser reflectance microscopy

por Thiagarajah, Jay R., Song, Yuanlin, Derichs, Nico, Verkman, A.S.
Publicado 2010

Evidence for modulation of pericryptal sheath myofibroblasts in rat descending colon by Transforming Growth Factor β and Angiotensin II.

por Thiagarajah, Jay R, Griffiths, Nina M, Pedley, Kevin C, Naftalin, Richard J
Publicado 2002

Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion

por Saslowsky, David E., Thiagarajah, Jay R., McCormick, Beth A., Lee, Jean C., Lencer, Wayne I.
Publicado 2016

Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling

por Chang, Denis, Whiteley, Aaron T., Bugda Gwilt, Katlynn, Lencer, Wayne I., Mekalanos, John J., Thiagarajah, Jay R.
Publicado 2020

Altered Goblet Cell Differentiation and Surface Mucus Properties in Hirschsprung Disease

por Thiagarajah, Jay R., Yildiz, Hasan, Carlson, Taylor, Thomas, Alyssa R., Steiger, Casey, Pieretti, Alberto, Zukerberg, Lawrence R., Carrier, Rebecca L., Goldstein, Allan M.
Publicado 2014

Gasdermin D pore-forming activity is redox-sensitive

por Devant, Pascal, Boršić, Elvira, Ngwa, Elsy M., Xiao, Haopeng, Chouchani, Edward T., Thiagarajah, Jay R., Hafner-Bratkovič, Iva, Evavold, Charles L., Kagan, Jonathan C.
Publicado 2023

CFTR Activator Increases Intestinal Fluid Secretion and Normalizes Stool Output in a Mouse Model of Constipation

por Cil, Onur, Phuan, Puay-Wah, Lee, Sujin, Tan, Joseph, Haggie, Peter M., Levin, Marc H., Sun, Liang, Thiagarajah, Jay R., Ma, Tonghui, Verkman, Alan S.
Publicado 2016

INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling

por Luong, Phi, Hedl, Matija, Yan, Jie, Zuo, Tao, Fu, Tian-Min, Jiang, Xiaomo, Thiagarajah, Jay R, Hansen, Steen H, Lesser, Cammie F, Wu, Hao, Abraham, Clara, Lencer, Wayne I
Publicado 2018

A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization

por Luong, Phi, Li, Qian, Chen, Pin-Fang, Wrighton, Paul J., Chang, Denis, Dwyer, Sean, Bayer, Marie-Theres, Snapper, Scott B., Hansen, Steen H., Thiagarajah, Jay R., Goessling, Wolfram, Lencer, Wayne I.
Publicado 2020

Patient-derived enteroids provide a platform for the development of therapeutic approaches in microvillus inclusion disease

por Kalashyan, Meri, Raghunathan, Krishnan, Oller, Haley, Bayer, Marie-Theres, Jimenez, Lissette, Roland, Joseph T., Kolobova, Elena, Hagen, Susan J., Goldsmith, Jeffrey D., Shub, Mitchell D., Goldenring, James R., Kaji, Izumi, Thiagarajah, Jay R.
Publicado 2023

The epithelial-specific ER stress sensor ERN2/IRE1β enables host-microbiota crosstalk to affect colon goblet cell development

por Grey, Michael J., De Luca, Heidi, Ward, Doyle V., Kreulen, Irini A.M., Bugda Gwilt, Katlynn, Foley, Sage E., Thiagarajah, Jay R., McCormick, Beth A., Turner, Jerrold R., Lencer, Wayne I.
Publicado 2022

Therapy Development for Microvillus Inclusion Disease using Patient-derived Enteroids

por Kalashyan, Meri, Raghunathan, Krishnan, Oller, Haley, Theres, Marie-Bayer, Jimenez, Lissette, Roland, Joseph T., Kolobova, Elena, Hagen, Susan J, Goldsmith, Jeffrey D., Shub, Mitchell D., Goldenring, James R., Kaji, Izumi, Thiagarajah, Jay R.
Publicado 2023

Congenital chloride-losing diarrhea in a Mexican child with the novel homozygous SLC26A3 mutation G393W

por Reimold, Fabian R., Balasubramanian, Savithri, Doroquez, David B., Shmukler, Boris E., Zsengeller, Zsuzsanna K., Saslowsky, David, Thiagarajah, Jay R., Stillman, Isaac E., Lencer, Wayne I., Wu, Bai-Lin, Villalpando-Carrion, Salvador, Alper, Seth L.
Publicado 2015

Novel variants in the stem cell niche factor WNT2B define the disease phenotype as a congenital enteropathy with ocular dysgenesis

por Zhang, Yanjia Jason, Jimenez, Lissette, Azova, Svetlana, Kremen, Jessica, Chan, Yee-Ming, Elhusseiny, Abdelrahman M., Saeed, Hajirah, Goldsmith, Jeffrey, Al-Ibraheemi, Alyaa, O’Connell, Amy E., Kovbasnjuk, Olga, Rodan, Lance, Agrawal, Pankaj B., Thiagarajah, Jay R.
Publicado 2021

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress

por Grey, Michael J., Cloots, Eva, Simpson, Mariska S., LeDuc, Nicole, Serebrenik, Yevgeniy V., De Luca, Heidi, De Sutter, Delphine, Luong, Phi, Thiagarajah, Jay R., Paton, Adrienne W., Paton, James C., Seeliger, Markus A., Eyckerman, Sven, Janssens, Sophie, Lencer, Wayne I.
Publicado 2020

Minimally Invasive Image-Guided Gut Transport Function Measurement Probe

por Otuya, David O., Gavgiotaki, Evangelia, Carlson, Camella J., Shi, Serena Q., Lee, Ariel J., Krall, Alexander A., Chung, Anita, Grant, Catriona G., Bhat, Nitasha M., Choy, Peter, Giddings, Sarah L., Gardecki, Joseph A., Thiagarajah, Jay R., Rowe, Steven M., Tearney, Guillermo J.
Publicado 2021