Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways

por Minato, Yusuke, Gohl, Daryl M., Thiede, Joshua M., Chacón, Jeremy M., Harcombe, William R., Maruyama, Fumito, Baughn, Anthony D.
Publicado 2019

Targeting intracellular p-aminobenzoic acid production potentiates the anti-tubercular action of antifolates

por Thiede, Joshua M., Kordus, Shannon L., Turman, Breanna J., Buonomo, Joseph A., Aldrich, Courtney C., Minato, Yusuke, Baughn, Anthony D.
Publicado 2016

Pyrazinamide Susceptibility Is Driven by Activation of the SigE-Dependent Cell Envelope Stress Response in Mycobacterium tuberculosis

por Thiede, Joshua M., Dillon, Nicholas A., Howe, Michael D., Aflakpui, Ranee, Modlin, Samuel J., Hoffner, Sven E., Valafar, Faramarz, Minato, Yusuke, Baughn, Anthony D.
Publicado 2022

Cephem‐Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis

por Cole, Malcolm S., Howe, Michael D., Buonomo, Joseph A., Sharma, Sachin, Lamont, Elise A., Brody, Scott I., Mishra, Neeraj K., Minato, Yusuke, Thiede, Joshua M., Baughn, Anthony D., Aldrich, Courtney C.
Publicado 2022

Immune Profiling to Determine Early Disease Trajectories Associated With Coronavirus Disease 2019 Mortality Rate: A Substudy from the ACTT-1 Trial

por Thiede, Joshua M, Gress, Abigail R, Libby, Samuel D, Ronayne, Christine E, Matchett, William E, Noren, Brooke, Billings, Joanne L, Menachery, Vineet D, Langlois, Ryan A, Kline, Susan, Bold, Tyler D
Publicado 2021

Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium

por Fiege, Jessica K., Thiede, Joshua M., Nanda, Hezkiel, Matchett, William E., Moore, Patrick J., Montanari, Noe Rico, Thielen, Beth K., Daniel, Jerry, Stanley, Emma, Hunter, Ryan C., Menachery, Vineet D., Shen, Steven S., Bold, Tyler D., Langlois, Ryan A.
Publicado 2020

Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium

por Fiege, Jessica K., Thiede, Joshua M., Nanda, Hezkiel Arya, Matchett, William E., Moore, Patrick J., Montanari, Noe Rico, Thielen, Beth K., Daniel, Jerry, Stanley, Emma, Hunter, Ryan C., Menachery, Vineet D., Shen, Steven S., Bold, Tyler D., Langlois, Ryan A.
Publicado 2021

A metabolic pathway for catabolizing levulinic acid in bacteria

por Rand, Jacqueline M., Pisithkul, Tippapha, Clark, Ryan L., Thiede, Joshua M., Mehrer, Christopher R., Agnew, Daniel E., Campbell, Candace E., Markley, Andrew L., Price, Morgan N., Ray, Jayashree, Wetmore, Kelly M., Suh, Yumi, Arkin, Adam P., Deutschbauer, Adam M., Amador-Noguez, Daniel, Pfleger, Brian F.
Publicado 2017

Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

por Ubah, Obinna C., Lake, Eric W., Gunaratne, Gihan S., Gallant, Joseph P., Fernie, Marie, Robertson, Austin J., Marchant, Jonathan S., Bold, Tyler D., Langlois, Ryan A., Matchett, William E., Thiede, Joshua M., Shi, Ke, Yin, Lulu, Moeller, Nicholas H., Banerjee, Surajit, Ferguson, Laura, Kovaleva, Marina, Porter, Andrew J., Aihara, Hideki, LeBeau, Aaron M., Barelle, Caroline J.
Publicado 2021