Translational PBPK Modeling of the Protein Therapeutic and CD95L Inhibitor Asunercept to Develop Dose Recommendations for Its First Use in Pediatric Glioblastoma Patients

por Hanke, Nina, Kunz, Claudia, Thiemann, Meinolf, Fricke, Harald, Lehr, Thorsten
Publicado 2019

Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in mice

por Gao, Liang, Brenner, David, Llorens-Bobadilla, Enric, Saiz-Castro, Gonzalo, Frank, Tobias, Wieghofer, Peter, Hill, Oliver, Thiemann, Meinolf, Karray, Saoussen, Prinz, Marco, Weishaupt, Jochen H., Martin-Villalba, Ana
Publicado 2015

A Single-Chain-Based Hexavalent CD27 Agonist Enhances T Cell Activation and Induces Anti-Tumor Immunity

por Thiemann, Meinolf, Richards, David M., Heinonen, Karl, Kluge, Michael, Marschall, Viola, Merz, Christian, Redondo Müller, Mauricio, Schnyder, Tim, Sefrin, Julian P., Sykora, Jaromir, Fricke, Harald, Gieffers, Christian, Hill, Oliver
Publicado 2018

The CD40 agonist HERA-CD40L results in enhanced activation of antigen presenting cells, promoting an anti-tumor effect alone and in combination with radiotherapy

por Frankish, Jamie, Mukherjee, Debayan, Romano, Erminia, Billian-Frey, Katharina, Schröder, Matthias, Heinonen, Karl, Merz, Christian, Redondo Müller, Mauricio, Gieffers, Christian, Hill, Oliver, Thiemann, Meinolf, Honeychurch, Jamie, Illidge, Tim, Sykora, Jaromir
Publicado 2023

HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality

por Richards, David M., Marschall, Viola, Billian-Frey, Katharina, Heinonen, Karl, Merz, Christian, Redondo Müller, Mauricio, Sefrin, Julian P., Schröder, Matthias, Sykora, Jaromir, Fricke, Harald, Hill, Oliver, Gieffers, Christian, Thiemann, Meinolf
Publicado 2019