Targeting histone lysine demethylases — Progress, challenges, and the future()

por Thinnes, Cyrille C., England, Katherine S., Kawamura, Akane, Chowdhury, Rasheduzzaman, Schofield, Christopher J., Hopkinson, Richard J.
Publicado 2014

Inhibition of JMJD6 by 2‐Oxoglutarate Mimics

por Islam, Md. Sailful, Thinnes, Cyrille C., Holt‐Martyn, James P., Chowdhury, Rasheduzzaman, McDonough, Michael A., Schofield, Christopher J.
Publicado 2021

Glucose Metabolism and Oxygen Availability Govern Reactivation of the Latent Human Retrovirus HTLV-1

por Kulkarni, Anurag, Mateus, Manuel, Thinnes, Cyrille C., McCullagh, James S., Schofield, Christopher J., Taylor, Graham P., Bangham, Charles R.M.
Publicado 2017

Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

por Baldini, Federico, Hertel, Johannes, Sandt, Estelle, Thinnes, Cyrille C., Neuberger-Castillo, Lorieza, Pavelka, Lukas, Betsou, Fay, Krüger, Rejko, Thiele, Ines
Publicado 2020

Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases

por Horita, Shoichiro, Scotti, John S., Thinnes, Cyrille, Mottaghi-Taromsari, Yousef S., Thalhammer, Armin, Ge, Wei, Aik, WeiShen, Loenarz, Christoph, Schofield, Christopher J., McDonough, Michael A.
Publicado 2015

Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible f...

por Kiriakidis, Serafim, Hoer, Simon S., Burrows, Natalie, Biddlecome, Gloria, Khan, Moddasar N., Thinnes, Cyrille C., Schofield, Christopher J., Rogers, Norma, Botto, Marina, Paleolog, Ewa, Maxwell, Patrick H.
Publicado 2017

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

por Thinnes, Cyrille C., Lohans, Christopher T., Abboud, Martine I., Yeh, Tzu‐Lan, Tumber, Anthony, Nowak, Radosław P., Attwood, Martin, Cockman, Matthew E., Oppermann, Udo, Loenarz, Christoph, Schofield, Christopher J.
Publicado 2019

A Novel Color Change Mechanism for Breast Cancer Biomarker Detection: Naphthoquinones as Specific Ligands of Human Arylamine N-Acetyltransferase 1

por Laurieri, Nicola, Egleton, James E., Varney, Amy, Thinnes, Cyrille C., Quevedo, Camilo E., Seden, Peter T., Thompson, Sam, Rodrigues-Lima, Fernando, Dairou, Julien, Dupret, Jean-Marie, Russell, Angela J., Sim, Edith
Publicado 2013

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease

por Hertel, Johannes, Harms, Amy C., Heinken, Almut, Baldini, Federico, Thinnes, Cyrille C., Glaab, Enrico, Vasco, Daniel A., Pietzner, Maik, Stewart, Isobel D., Wareham, Nicholas J., Langenberg, Claudia, Trenkwalder, Claudia, Krüger, Rejko, Hankemeier, Thomas, Fleming, Ronan M.T., Mollenhauer, Brit, Thiele, Ines
Publicado 2019

APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites

por Heinken, Almut, Hulshof, Timothy Otto, Nap, Bram, Martinelli, Filippo, Basile, Arianna, O'Brolchain, Amy, O’Sullivan, Neil Francis, Gallagher, Celine, Magee, Eimer, McDonagh, Francesca, Lalor, Ian, Bergin, Maeve, Evans, Phoebe, Daly, Rachel, Farrell, Ronan, Delaney, Rose Marie, Hill, Saoirse, McAuliffe, Saoirse Roisin, Kilgannon, Trevor, Fleming, Ronan M.T., Thinnes, Cyrille C., Thiele, Ines
Publicado 2023

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

por Yeh, Tzu-Lan, Leissing, Thomas M., Abboud, Martine I., Thinnes, Cyrille C., Atasoylu, Onur, Holt-Martyn, James P., Zhang, Dong, Tumber, Anthony, Lippl, Kerstin, Lohans, Christopher T., Leung, Ivanhoe K. H., Morcrette, Helen, Clifton, Ian J., Claridge, Timothy D. W., Kawamura, Akane, Flashman, Emily, Lu, Xin, Ratcliffe, Peter J., Chowdhury, Rasheduzzaman, Pugh, Christopher W., Schofield, Christopher J.
Publicado 2017