Characterization of Cortical Glial Scars in the Diisopropylfluorophosphate (DFP) Rat Model of Epilepsy

por Gage, Meghan, Gard, Megan, Thippeswamy, Thimmasettappa
Publicado 2022

Seizure-Induced Oxidative Stress in Temporal Lobe Epilepsy

por Puttachary, Sreekanth, Sharma, Shaunik, Stark, Sara, Thippeswamy, Thimmasettappa
Publicado 2015

Gut dysbiosis following organophosphate, diisopropylfluorophosphate (DFP), intoxication and saracatinib oral administration

por Gage, Meghan, Vinithakumari, Akhil A., Mooyottu, Shankumar, Thippeswamy, Thimmasettappa
Publicado 2022

The effects of Src tyrosine kinase inhibitor, saracatinib, on the markers of epileptogenesis in a mixed-sex cohort of adult rats in the kainic acid model of epilepsy

por Rao, Nikhil S., Putra, Marson, Meyer, Christina, Almanza, Aida, Thippeswamy, Thimmasettappa
Publicado 2023

Fyn-tau Ablation Modifies PTZ-Induced Seizures and Post-seizure Hallmarks of Early Epileptogenesis

por Putra, Marson, Puttachary, Sreekanth, Liu, Guanghao, Lee, Gloria, Thippeswamy, Thimmasettappa
Publicado 2020

Advantages of Repeated Low Dose against Single High Dose of Kainate in C57BL/6J Mouse Model of Status Epilepticus: Behavioral and Electroencephalographic Studies

por Tse, Karen, Puttachary, Sreekanth, Beamer, Edward, Sills, Graeme J., Thippeswamy, Thimmasettappa
Publicado 2014

Status Epilepticus: Behavioral and Electroencephalography Seizure Correlates in Kainate Experimental Models

por Sharma, Shaunik, Puttachary, Sreekanth, Thippeswamy, Achala, Kanthasamy, Anumantha G., Thippeswamy, Thimmasettappa
Publicado 2018

The male sex pheromone darcin stimulates hippocampal neurogenesis and cell proliferation in the subventricular zone in female mice

por Hoffman, Emma, Pickavance, Lucy, Thippeswamy, Thimmasettappa, Beynon, Robert J., Hurst, Jane L.
Publicado 2015

Exploring the benefits of in-diet versus repeated oral dosing of saracatinib (AZD0530) in chronic studies: insights into pharmacokinetics and animal welfare

por Vasanthi, Suraj S., Massey, Nyzil, Nair, Suresh N., Mochel, Jonathan P., Showman, Lucas, Thippeswamy, Thimmasettappa
Publicado 2023

Immediate Epileptogenesis after Kainate-Induced Status Epilepticus in C57BL/6J Mice: Evidence from Long Term Continuous Video-EEG Telemetry

por Puttachary, Sreekanth, Sharma, Shaunik, Tse, Karen, Beamer, Edward, Sexton, Abby, Crutison, Joseph, Thippeswamy, Thimmasettappa
Publicado 2015

The Impacts of Surgery and Intracerebral Electrodes in C57BL/6J Mouse Kainate Model of Epileptogenesis: Seizure Threshold, Proteomics, and Cytokine Profiles

por Tse, Karen, Beamer, Edward, Simpson, Deborah, Beynon, Robert J., Sills, Graeme J., Thippeswamy, Thimmasettappa
Publicado 2021

Mechanisms of disease-modifying effect of saracatinib (AZD0530), a Src/Fyn tyrosine kinase inhibitor, in the rat kainate model of temporal lobe epilepsy

por Sharma, Shaunik, Carlson, Steven, Gregory-Flores, Adriana, Hinojo-Perez, Andy, Olson, Ashley, Thippeswamy, Thimmasettappa
Publicado 2021

1400 W, a selective inducible nitric oxide synthase inhibitor, mitigates early neuroinflammation and nitrooxidative stress in diisopropylfluorophosphate-induced short-term neurotox...

por Massey, Nyzil, Vasanthi, Suraj Sundara, Samidurai, Manikandan, Gage, Meghan, Rao, Nikhil, Meyer, Christina, Thippeswamy, Thimmasettappa
Publicado 2023

Differential Impact of Severity and Duration of Status Epilepticus, Medical Countermeasures, and a Disease-Modifier, Saracatinib, on Brain Regions in the Rat Diisopropylfluorophosp...

por Gage, Meghan, Putra, Marson, Gomez-Estrada, Crystal, Golden, Madison, Wachter, Logan, Gard, Megan, Thippeswamy, Thimmasettappa
Publicado 2021

Saracatinib, a Src Tyrosine Kinase Inhibitor, as a Disease Modifier in the Rat DFP Model: Sex Differences, Neurobehavior, Gliosis, Neurodegeneration, and Nitro-Oxidative Stress

por Gage, Meghan, Putra, Marson, Wachter, Logan, Dishman, Kylie, Gard, Megan, Gomez-Estrada, Crystal, Thippeswamy, Thimmasettappa
Publicado 2021

Sex‐based structural and functional MRI outcomes in the rat brain after soman (GD) exposure‐induced status epilepticus

por Gage, Meghan, Vasanthi, Suraj S, Meyer, Christina M, Rao, Nikhil S, Thedens, Daniel R, Kannurpatti, Sridhar S., Thippeswamy, Thimmasettappa
Publicado 2023

Soman (GD) Rat Model to Mimic Civilian Exposure to Nerve Agent: Mortality, Video-EEG Based Status Epilepticus Severity, Sex Differences, Spontaneously Recurring Seizures, and Brain...

por Gage, Meghan, Rao, Nikhil S., Samidurai, Manikandan, Putra, Marson, Vasanthi, Suraj S., Meyer, Christina, Wang, Chong, Thippeswamy, Thimmasettappa
Publicado 2022

Peripheral and central effects of NADPH oxidase inhibitor, mitoapocynin, in a rat model of diisopropylfluorophosphate (DFP) toxicity

por Meyer, Christina, Rao, Nikhil S., Vasanthi, Suraj S., Pereira, Beatriz, Gage, Meghan, Putra, Marson, Holtkamp, Claire, Huss, Joselyn, Thippeswamy, Thimmasettappa
Publicado 2023

DFP-Induced Status Epilepticus Severity in Mixed-Sex Cohorts of Adult Rats Housed in the Same Room: Behavioral and EEG Comparisons

por Rao, Nikhil S., Meyer, Christina, Vasanthi, Suraj S., Massey, Nyzil, Samidurai, Manikandan, Gage, Meghan, Putra, Marson, Almanza, Aida N., Wachter, Logan, Thippeswamy, Thimmasettappa
Publicado 2022

Disease-Modifying Effects of a Glial-targeted Inducible Nitric Oxide Synthase Inhibitor (1400W) in Mixed-sex Cohorts of a Rat Soman (GD) Model of Epilepsy

por Vasanthi, Suraj S., Rao, Nikhil S., Samidurai, Manikandan, Massey, Nyzil, Meyer, Christina, Gage, Meghan, Kharate, Mihir, Almanza, Aida, Wachter, Logan, Mafuta, Candide, Trevino, Lily, Carlo, Adriana M, Bryant, Elijah, Corson, Brooke E., Wohlgemuth, Morgan, Ostrander, Morgan, Wang, Chong, Thippeswamy, Thimmasettappa
Publicado 2023