CD8(+) T-cell cross-competition is governed by peptide–MHC class I stability

por Galea, Ian, Stasakova, Jana, Dunscombe, Melanie S, Ottensmeier, Christian H, Elliott, Tim, Thirdborough, Stephen M
Publicado 2012

Fcγ receptor–mediated cross-linking codefines the immunostimulatory activity of anti-human CD96 antibodies

por Rogel, Anne, Ibrahim, Fathima M., Thirdborough, Stephen M., Renart-Depontieu, Florence, Birts, Charles N., Buchan, Sarah L., Preville, Xavier, King, Emma V., Al-Shamkhani, Aymen
Publicado 2022

Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR‐200 levels in extracellular vesicles

por Bhome, Rahul, Emaduddin, Muhammad, James, Victoria, House, Louise M., Thirdborough, Stephen M., Mellone, Massimiliano, Tulkens, Joeri, Primrose, John N., Thomas, Gareth J., De Wever, Olivier, Mirnezami, Alex H., Sayan, A. Emre
Publicado 2022

Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer

por Ward, M J, Thirdborough, S M, Mellows, T, Riley, C, Harris, S, Suchak, K, Webb, A, Hampton, C, Patel, N N, Randall, C J, Cox, H J, Jogai, S, Primrose, J, Piper, K, Ottensmeier, C H, King, E V, Thomas, G J
Publicado 2014

Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression

por Bhome, Rahul, Goh, Rebecca W., Bullock, Marc D., Pillar, Nir, Thirdborough, Stephen M., Mellone, Massimiliano, Mirnezami, Reza, Galea, Dieter, Veselkov, Kirill, Gu, Quan, Underwood, Timothy J., Primrose, John N., De Wever, Olivier, Shomron, Noam, Sayan, A. Emre, Mirnezami, Alex H.
Publicado 2017

Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4

por Hanley, Christopher J, Mellone, Massimiliano, Ford, Kirsty, Thirdborough, Steve M, Mellows, Toby, Frampton, Steven J, Smith, David M, Harden, Elena, Szyndralewiez, Cedric, Bullock, Marc, Noble, Fergus, Moutasim, Karwan A, King, Emma V, Vijayanand, Pandurangan, Mirnezami, Alex H, Underwood, Timothy J, Ottensmeier, Christian H, Thomas, Gareth J
Publicado 2017

LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation

por Yeboah, Muchaala, Papagregoriou, Charys, Jones, Des C., Chan, H.T. Claude, Hu, Guangan, McPartlan, Justine S., Schiött, Torbjörn, Mattson, Ulrika, Mockridge, C. Ian, Tornberg, Ulla-Carin, Hambe, Björn, Ljungars, Anne, Mattsson, Mikael, Tews, Ivo, Glennie, Martin J., Thirdborough, Stephen M., Trowsdale, John, Frendeus, Björn, Chen, Jianzhu, Cragg, Mark S., Roghanian, Ali
Publicado 2020

Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment

por Turaj, Anna H., Hussain, Khiyam, Cox, Kerry L., Rose-Zerilli, Matthew J.J., Testa, James, Dahal, Lekh N., Chan, H.T. Claude, James, Sonya, Field, Vikki L., Carter, Matthew J., Kim, Hyung J., West, Jonathan J., Thomas, Lawrence J., He, Li-Zhen, Keler, Tibor, Johnson, Peter W.M., Al-Shamkhani, Aymen, Thirdborough, Stephen M., Beers, Stephen A., Cragg, Mark S., Glennie, Martin J., Lim, Sean H.
Publicado 2017

HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy

por Hussain, Khiyam, Liu, Rena, Smith, Rosanna C. G., Müller, Kri T. J., Ghorbani, Mohammadmersad, Macari, Sofia, Cleary, Kirstie L. S., Oldham, Robert J., Foxall, Russell B., James, Sonya, Booth, Steven G., Murray, Tom, Dahal, Lekh N., Hargreaves, Chantal E., Kemp, Robert S., Longley, Jemma, Douglas, James, Markham, Hannah, Chee, Serena J., Stopforth, Richard J., Roghanian, Ali, Carter, Matthew J., Ottensmeier, Christian H., Frendéus, Bjorn, Cutress, Ramsey I., French, Ruth R., Glennie, Martin J., Strefford, Jonathan C., Thirdborough, Stephen M., Beers, Stephen A., Cragg, Mark S.
Publicado 2022