The Remarkable Selectivity of Nirmatrelvir

por Duveau, Damien Y., Thomas, Craig J.
Publicado 2022

PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers

por Eastman, Richard T., Khine, Pwint, Huang, Ruili, Thomas, Craig J., Su, Xin-zhuan
Publicado 2016

Drug resistant integrase mutants cause aberrant HIV integrations

por Varadarajan, Janani, McWilliams, Mary Jane, Mott, Bryan T., Thomas, Craig J., Smith, Steven J., Hughes, Stephen H.
Publicado 2016

KiRNet: Kinase-centered network propagation of pharmacological screen results

por Bello, Thomas, Chan, Marina, Golkowski, Martin, Xue, Andrew G., Khasnavis, Nithisha, Ceribelli, Michele, Ong, Shao-En, Thomas, Craig J., Gujral, Taranjit S.
Publicado 2021

Quantitative High-Throughput Screen Identifies Inhibitors of the Schistosoma mansoni Redox Cascade

por Simeonov, Anton, Jadhav, Ajit, Sayed, Ahmed A., Wang, Yuhong, Nelson, Michael E., Thomas, Craig J., Inglese, James, Williams, David L., Austin, Christopher P.
Publicado 2008

Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wil...

por Vazquez-Ortiz, Guelaguetza, Chisholm, Cristine, Xu, Xiaoling, Lahusen, Tyler J, Li, Cuiling, Sakamuru, Srilatha, Huang, Ruili, Thomas, Craig J, Xia, Menghang, Deng, Chuxia
Publicado 2014

Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants

por Smith, Steven J., Pauly, Gary T., Akram, Aamir, Melody, Kevin, Rai, Ganesha, Maloney, David J., Ambrose, Zandrea, Thomas, Craig J., Schneider, Joel T., Hughes, Stephen H.
Publicado 2016

Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna(®)) with the human ABC drug transporter P-glycoprotein

por Shukla, Suneet, Chufan, Eduardo E., Singh, Satyakam, Skoumbourdis, Amanda P., Kapoor, Khyati, Boxer, Matthew B., Duveau, Damien Y., Thomas, Craig J., Talele, Tanaji T., Ambudkar, Suresh V.
Publicado 2014

A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology

por Burgess, Teresa L., Amason, Joshua D., Rubin, Jeffrey S., Duveau, Damien Y., Lamy, Laurence, Roberts, David D., Farrell, Catherine L., Inglese, James, Thomas, Craig J., Miller, Thomas W.
Publicado 2020

O-GlcNAc regulates gene expression by controlling detained intron splicing

por Tan, Zhi-Wei, Fei, George, Paulo, Joao A, Bellaousov, Stanislav, Martin, Sara E S, Duveau, Damien Y, Thomas, Craig J, Gygi, Steven P, Boutz, Paul L, Walker, Suzanne
Publicado 2020

Enhanced efficacy of JAK1 inhibitor with mTORC1/C2 targeting in smoldering/chronic adult T cell leukemia

por Daenthanasanmak, Anusara, Lin, Yuquan, Zhang, Meili, Bryant, Bonita R., Petrus, Michael N., Bamford, Richard N., Thomas, Craig J., Miljkovic, Milos D., Conlon, Kevin C., Waldmann, Thomas A.
Publicado 2020

Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins

por Antignani, Antonella, Mathews Griner, Lesley, Guha, Rajarshi, Simon, Nathan, Pasetto, Matteo, Keller, Jonathan, Huang, Manjie, Angelus, Evan, Pastan, Ira, Ferrer, Marc, FitzGerald, David J., Thomas, Craig J.
Publicado 2016

Inhibition of MAPK‐Erk pathway in vivo attenuates aortic valve disease processes in Emilin1‐deficient mouse model

por Munjal, Charu, Jegga, Anil G., Opoka, Amy M., Stoilov, Ivan, Norris, Russell A., Thomas, Craig J., Smith, J. Michael, Mecham, Robert P., Bressan, Giorgio M., Hinton, Robert B.
Publicado 2017

Matrix Drug Screen Identifies Synergistic Drug Combinations to Augment SMAC Mimetic Activity in Ovarian Cancer

por Noonan, Anne M., Cousins, Amanda, Anderson, David, Zeligs, Kristen P., Bunch, Kristen, Hernandez, Lidia, Shibuya, Yusuke, Goldlust, Ian S., Guha, Rajarshi, Ferrer, Marc, Thomas, Craig J., Annunziata, Christina M.
Publicado 2020

Large-scale pharmacological profiling of 3D tumor models of cancer cells

por Mathews Griner, Lesley A, Zhang, Xiaohu, Guha, Rajarshi, McKnight, Crystal, Goldlust, Ian S, Lal-Nag, Madhu, Wilson, Kelli, Michael, Sam, Titus, Steve, Shinn, Paul, Thomas, Craig J, Ferrer, Marc
Publicado 2016

Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death

por Zhu, Ping Jun, Hobson, John P., Southall, Noel, Qiu, Cunping, Thomas, Craig J., Lu, Jiamo, Inglese, James, Zheng, Wei, Leppla, Stephen H., Bugge, Thomas H., Austin, Christopher P., Liu, Shihui
Publicado 2009

CD28 and ITK signals regulate autoreactive T cell trafficking

por Jain, Nitya, Miu, Bing, Jiang, Jian-kang, McKinstry, Kai K., Prince, Amanda, Swain, Susan L, Greiner, Dale L., Thomas, Craig J., Sanderson, Michael J., Berg, Leslie J, Kang, Joonsoo
Publicado 2013

Characterization of clinically used oral antiseptics as quadruplex-binding ligands

por Calabrese, David R, Zlotkowski, Katherine, Alden, Stephanie, Hewitt, William M, Connelly, Colleen M, Wilson, Robert M, Gaikwad, Snehal, Chen, Lu, Guha, Rajarshi, Thomas, Craig J, Mock, Beverly A, Schneekloth, John S
Publicado 2018

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

por Venkatesh, Humsa S., Tam, Lydia T., Woo, Pamelyn J., Lennon, James, Nagaraja, Surya, Gillespie, Shawn M., Ni, Jing, Duveau, Damien Y., Morris, Patrick J., Zhao, Jean J., Thomas, Craig J., Monje, Michelle
Publicado 2017

The Inhibition and Treatment of Breast Cancer with Poly (ADP-ribose) Polymerase (PARP-1) Inhibitors

por De Soto, Joseph A., Wang, Xianyan, Tominaga, Yohei, Wang, Rui-Hong, Cao, Liu, Qiao, Wenhui, Li, Cuiling, Xu, Xiaoling, Skoumbourdis, Amanda P., Prindiville, Sheila A., Thomas, Craig J., Deng, Chu-Xia
Publicado 2006