Editorial

por Thomas, David Y.
Publicado 2017

Refining Protein Subcellular Localization

por Scott, Michelle S, Calafell, Sara J, Thomas, David Y, Hallett, Michael T
Publicado 2005

Variable Responses to CFTR Correctors in vitro: Estimating the Design Effect in Precision Medicine

por Matthes, Elizabeth, Goepp, Julie, Martini, Carolina, Shan, Jiajie, Liao, Jie, Thomas, David Y., Hanrahan, John W.
Publicado 2018

Proteomic Analysis of Rough and Smooth Endoplasmic Reticulum

por Paiement, Jacques, Roy, Line, Gilchrist, Annalyn, Bell, Alex, Kearney, Rob, Thomas, David Y., Bergeron, John J.M.
Publicado 2002

A Biochemical Genomics Screen for Substrates of Ste20p Kinase Enables the In Silico Prediction of Novel Substrates

por Annan, Robert B., Lee, Anna Y., Reid, Ian D., Sayad, Azin, Whiteway, Malcolm, Hallett, Michael, Thomas, David Y.
Publicado 2009

Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium

por Sato, Yukiko, Mustafina, Kamila R., Luo, Yishan, Martini, Carolina, Thomas, David Y., Wiseman, Paul W., Hanrahan, John W.
Publicado 2021

Intracellular Eukaryotic Parasites Have a Distinct Unfolded Protein Response

por Gosline, Sara J. C., Nascimento, Mirna, McCall, Laura-Isobel, Zilberstein, Dan, Thomas, David Y., Matlashewski, Greg, Hallett, Michael
Publicado 2011

Combination of Selective PARP3 and PARP16 Inhibitory Analogues of Latonduine A Corrects F508del-CFTR Trafficking

por Centko, Ryan M., Carlile, Graeme W., Barne, Isabel, Patrick, Brian O., Blagojevic, Polina, Thomas, David Y., Andersen, Raymond J.
Publicado 2020

A novel triple combination of pharmacological chaperones improves F508del-CFTR correction

por Carlile, Graeme W., Yang, Qi, Matthes, Elizabeth, Liao, Jie, Radinovic, Stevo, Miyamoto, Carol, Robert, Renaud, Hanrahan, John W., Thomas, David Y.
Publicado 2018

gp25L/emp24/p24 Protein Family Members of the cis-Golgi Network Bind Both COP I and II Coatomer

por Dominguez, Michel, Dejgaard, Kurt, Füllekrug, Joachim, Dahan, Sophie, Fazel, Ali, Paccaud, Jean-Pierre, Thomas, David Y., Bergeron, John J. M., Nilsson, Tommy
Publicado 1998

A Role for Myosin-I in Actin Assembly through Interactions with Vrp1p, Bee1p, and the Arp2/3 Complex

por Evangelista, Marie, Klebl, Bert M., Tong, Amy H.Y., Webb, Bradley A., Leeuw, Thomas, Leberer, Ekkehard, Whiteway, Malcolm, Thomas, David Y., Boone, Charles
Publicado 2000

Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence

por Epp, Elias, Vanier, Ghyslaine, Harcus, Doreen, Lee, Anna Y., Jansen, Gregor, Hallett, Michael, Sheppard, Don C., Thomas, David Y., Munro, Carol A., Mullick, Alaka, Whiteway, Malcolm
Publicado 2010

Chemogenomic profiling predicts antifungal synergies

por Jansen, Gregor, Lee, Anna Y, Epp, Elias, Fredette, Amélie, Surprenant, Jamie, Harcus, Doreen, Scott, Michelle, Tan, Elaine, Nishimura, Tamiko, Whiteway, Malcolm, Hallett, Michael, Thomas, David Y
Publicado 2009

Ouabain Mimics Low Temperature Rescue of F508del-CFTR in Cystic Fibrosis Epithelial Cells

por Zhang, Donglei, Ciciriello, Fabiana, Anjos, Suzana M., Carissimo, Annamaria, Liao, Jie, Carlile, Graeme W., Balghi, Haouaria, Robert, Renaud, Luini, Alberto, Hanrahan, John W., Thomas, David Y.
Publicado 2012

Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands

por Brahimi, Fouad, Galan, Alba, Jmaeff, Sean, Barcelona, Pablo F., De Jay, Nicolas, Dejgaard, Kurt, Young, Jason C., Kleinman, Claudia L., Thomas, David Y., Saragovi, H. Uri
Publicado 2020

The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway

por Carlile, Graeme W., Yang, Qi, Matthes, Elizabeth, Liao, Jie, Birault, Véronique, Sneddon, Helen F., Poole, Darren L., Hall, Callum J., Hanrahan, John W., Thomas, David Y.
Publicado 2022

Compounds that correct F508del-CFTR trafficking can also correct other protein trafficking diseases: an in vitro study using cell lines

por Sampson, Heidi M, Lam, Hung, Chen, Pei-Chun, Zhang, Donglei, Mottillo, Cristina, Mirza, Myriam, Qasim, Karim, Shrier, Alvin, Shyng, Show-Ling, Hanrahan, John W, Thomas, David Y
Publicado 2013

Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A

por Lopes-Pacheco, Miquéias, Bacalhau, Mafalda, Ramalho, Sofia S., Silva, Iris A. L., Ferreira, Filipa C., Carlile, Graeme W., Thomas, David Y., Farinha, Carlos M., Hanrahan, John W., Amaral, Margarida D.
Publicado 2022

Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR

por Stevers, Loes M., Wolter, Madita, Carlile, Graeme W., Macdonald, Dwight, Richard, Luc, Gielkens, Frank, Hanrahan, John W., Thomas, David Y., Chakka, Sai Kumar, Peterson, Mark L., Thomas, Helmut, Brunsveld, Luc, Ottmann, Christian
Publicado 2022

Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent...

por Goldberg, Alexander A., Richard, Vincent R., Kyryakov, Pavlo, Bourque, Simon D., Beach, Adam, Burstein, Michelle T., Glebov, Anastasia, Koupaki, Olivia, Boukh-Viner, Tatiana, Gregg, Christopher, Juneau, Mylène, English, Ann M., Thomas, David Y., Titorenko, Vladimir I.
Publicado 2010