The Trypanosomatid Pr77-hallmark contains a downstream core promoter element essential for transcription activity of the Trypanosoma cruzi L1Tc retrotransposon

por Macías, Francisco, López, Manuel Carlos, Thomas, M. Carmen
Publicado 2016

The L1Tc non-LTR retrotransposon of Trypanosoma cruzi contains an internal RNA-pol II-dependent promoter that strongly activates gene transcription and generates unspliced transcri...

por Heras, Sara R., López, Manuel C., Olivares, Mónica, Thomas, M. Carmen
Publicado 2007

The SIDER2 elements, interspersed repeated sequences that populate the Leishmania genomes, constitute subfamilies showing chromosomal proximity relationship

por Requena, Jose M, Folgueira, Cristina, López, Manuel C, Thomas, M Carmen
Publicado 2008

TBP and SNAP50 transcription factors bind specifically to the Pr77 promoter sequence from trypanosomatid non-LTR retrotransposons

por Macías, Francisco, Afonso-Lehmann, Raquel, Carreira, Patricia E., Thomas, M. Carmen
Publicado 2021

Pr77 and L1TcRz: A dual system within the 5′-end of L1Tc retrotransposon, internal promoter and HDV-like ribozyme

por Sánchez-Luque, Francisco, López, Manuel C., Macias, Francisco, Alonso, Carlos, Thomas, M. Carmen
Publicado 2012

Biology of Trypanosoma cruzi Retrotransposons: From an Enzymatic to a Structural Point of View

por Macías, Francisco, Afonso-Lehmann, Raquel, López, Manuel C., Gómez, Inmaculada, Thomas, M. Carmen
Publicado 2018

Identification of an hepatitis delta virus-like ribozyme at the mRNA 5′-end of the L1Tc retrotransposon from Trypanosoma cruzi

por Sánchez-Luque, Francisco J., López, Manuel C., Macias, Francisco, Alonso, Carlos, Thomas, M. Carmen
Publicado 2011

Dataset for distribution of SIDER2 elements in the Leishmania major genome and transcriptome

por Requena, Jose M., Rastrojo, Alberto, Garde, Esther, López, Manuel C., Thomas, M. Carmen, Aguado, Begoña
Publicado 2017

Nucleic-acid-binding properties of the C2-L1Tc nucleic acid chaperone encoded by L1Tc retrotransposon

por Heras, Sara R., Thomas, M. Carmen, Macias, Francisco, Patarroyo, Manuel E., Alonso, Carlos, López, Manuel C.
Publicado 2009

Differential Phenotypic and Functional Profiles of TcCA-2 -Specific Cytotoxic CD8(+) T Cells in the Asymptomatic versus Cardiac Phase in Chagasic Patients

por Egui, Adriana, Thomas, M. Carmen, Carrilero, Bartolomé, Segovia, Manuel, Alonso, Carlos, Marañón, Concepción, López, Manuel Carlos
Publicado 2015

Identification of a type I nitroreductase gene in non-virulent Trypanosoma rangeli

por Montenegro, Marjorie, Cuervo, Claudia, Cardenas, Constanza, Duarte, Silvia, Díaz, Jenny R, Thomas, M Carmen, Lopez, Manuel C, Puerta, Concepcion J
Publicado 2017

Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4(+)CD8(+) T cells in chronic Chagas disease patients

por Pérez-Antón, Elena, Egui, Adriana, Thomas, M. Carmen, Puerta, Concepción J., González, John Mario, Cuéllar, Adriana, Segovia, Manuel, López, Manuel Carlos
Publicado 2018

A proportion of CD4(+) T cells from patients with chronic Chagas disease undergo a dysfunctional process, which is partially reversed by benznidazole treatment

por Pérez-Antón, Elena, Egui, Adriana, Thomas, M. Carmen, Carrilero, Bartolomé, Simón, Marina, López-Ruz, Miguel Ángel, Segovia, Manuel, López, Manuel Carlos
Publicado 2021

Differential expression profile of genes involved in the immune response associated to progression of chronic Chagas disease

por Gómez, Inmaculada, López, Manuel Carlos, Egui, Adriana, Palacios, Génesis, Carrilero, Bartolomé, Benítez, Celia, Simón, Marina, Segovia, Manuel, Carmelo, Emma, Thomas, M Carmen
Publicado 2023

Short-term follow-up of chagasic patients after benznidazole treatment using multiple serological markers

por Fernández-Villegas, Ana, Pinazo, María Jesús, Marañón, Concepción, Thomas, M Carmen, Posada, Elizabeth, Carrilero, Bartolomé, Segovia, Manuel, Gascon, Joaquim, López, Manuel C
Publicado 2011

Promiscuous Recognition of a Trypanosoma cruzi CD8(+) T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients

por Lasso, Paola, Beltrán, Lina, Guzmán, Fanny, Rosas, Fernando, Thomas, M. Carmen, López, Manuel Carlos, González, John Mario, Cuéllar, Adriana, Puerta, Concepción J.
Publicado 2016

Differential Expression of Immune Response Genes in Asymptomatic Chronic Chagas Disease Patients Versus Healthy Subjects

por Gómez, Inmaculada, Thomas, M. Carmen, Palacios, Génesis, Egui, Adriana, Carrilero, Bartolomé, Simón, Marina, Valladares, Basilio, Segovia, Manuel, Carmelo, Emma, López, Manuel Carlos
Publicado 2021

CD8(+) T Cell Response Quality Is Related to Parasite Control in an Animal Model of Single and Mixed Chronic Trypanosoma cruzi Infections

por Mateus, Jose, Nocua, Paola, Lasso, Paola, López, Manuel Carlos, Thomas, M. Carmen, Egui, Adriana, Cuervo, Claudia, González, John Mario, Puerta, Concepción J., Cuéllar, Adriana
Publicado 2021

Phenotypic and Functional Profiles of Antigen-Specific CD4(+) and CD8(+) T Cells Associated With Infection Control in Patients With Cutaneous Leishmaniasis

por Egui, Adriana, Ledesma, Darién, Pérez-Antón, Elena, Montoya, Andrés, Gómez, Inmaculada, Robledo, Sara María, Infante, Juan José, Vélez, Ivan Darío, López, Manuel C., Thomas, M. Carmen
Publicado 2018

Draft Genome Sequence of the Trypanosoma cruzi B. M. López Strain (TcIa), Isolated from a Colombian Patient

por Gómez, Inmaculada, Rastrojo, Alberto, Sanchez-Luque, Francisco José, Lorenzo-Díaz, Fabián, Macías, Francisco, Valladares, Basilio, Aguado, Begoña, Requena, José María, López, Manuel Carlos, Thomas, M. Carmen
Publicado 2020