Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease

por Thome, Aaron D., Standaert, David G., Harms, Ashley S.
Publicado 2015

Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson’s disease

por Williams, Gregory P., Schonhoff, Aubrey M., Jurkuvenaite, Asta, Thome, Aaron D., Standaert, David G., Harms, Ashley S.
Publicado 2018

α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration

por Harms, Ashley S., Delic, Vedad, Thome, Aaron D., Bryant, Nicole, Liu, Zhiyong, Chandra, Sidhanth, Jurkuvenaite, Asta, West, Andrew B.
Publicado 2017

Extracellular Vesicles Derived From Ex Vivo Expanded Regulatory T Cells Modulate In Vitro and In Vivo Inflammation

por Thome, Aaron D., Thonhoff, Jason R., Zhao, Weihua, Faridar, Alireza, Wang, Jinghong, Beers, David R., Appel, Stanley H.
Publicado 2022

Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS

por Beers, David R., Thonhoff, Jason R., Faridar, Alireza, Thome, Aaron D., Zhao, Weihua, Wen, Shixiang, Appel, Stanley H.
Publicado 2022

Serum programmed cell death proteins in amyotrophic lateral sclerosis

por Beers, David R., Zhao, Weihua, Thonhoff, Jason R., Faridar, Alireza, Thome, Aaron D., Wen, Shixiang, Wang, Jinghong, Appel, Stanley H.
Publicado 2021

Restoring regulatory T-cell dysfunction in Alzheimer’s disease through ex vivo expansion

por Faridar, Alireza, Thome, Aaron D, Zhao, Weihua, Thonhoff, Jason R, Beers, David R, Pascual, Belen, Masdeu, Joseph C, Appel, Stanley H
Publicado 2020

Functional alterations of myeloid cells during the course of Alzheimer’s disease

por Thome, Aaron D., Faridar, Alireza, Beers, David R., Thonhoff, Jason R., Zhao, Weihua, Wen, Shixiang, Pascual, Belen, Masdeu, Joseph C., Appel, Stanley H.
Publicado 2018

Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis

por Beers, David R., Zhao, Weihua, Neal, Daniel W., Thonhoff, Jason R., Thome, Aaron D., Faridar, Alireza, Wen, Shixiang, Wang, Jinghong, Appel, Stanley H.
Publicado 2020

Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson’s disease

por Thome, Aaron D., Atassi, Farah, Wang, Jinghong, Faridar, Alireza, Zhao, Weihua, Thonhoff, Jason R., Beers, David R., Lai, Eugene C., Appel, Stanley H.
Publicado 2021

Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls

por Zhao, Weihua, Beers, David R., Thonhoff, Jason R., Thome, Aaron D., Faridar, Alireza, Wang, Jinghong, Wen, Shixiang, Ornelas, Loren, Sareen, Dhruv, Goodridge, Helen S., Svendsen, Clive N., Appel, Stanley H.
Publicado 2020

A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer’s disease

por Faridar, Alireza, Eid, Abdulmunaim M., Thome, Aaron D., Zhao, Weihua, Beers, David R., Pascual, Maria B., Nakawah, Mohammad O., Roman, Gustavo C., Davis, Charles S., Grundman, Michael, Masdeu, Joseph C., Appel, Stanley H.
Publicado 2023

Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis

por Thonhoff, Jason R., Berry, James D., Macklin, Eric A., Beers, David R., Mendoza, Patricia A., Zhao, Weihua, Thome, Aaron D., Triolo, Fabio, Moon, James J., Paganoni, Sabrina, Cudkowicz, Merit, Appel, Stanley H.
Publicado 2022

Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer’s disease

por Faridar, Alireza, Vasquez, Matthew, Thome, Aaron D., Yin, Zheng, Xuan, Hui, Wang, Jing Hong, Wen, Shixiang, Li, Xuping, Thonhoff, Jason R., Zhao, Weihua, Zhao, Hong, Beers, David R., Wong, Stephen T. C., Masdeu, Joseph C., Appel, Stanley H.
Publicado 2022