Mechanical strain disrupts primary cilia structure and modulates hedgehog signalling in adult chondrocytes

por Thompson, CL, Chapple, JP, Knight, MM
Publicado 2012

Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes

por Thompson, C.L., Chapple, J.P., Knight, M.M.
Publicado 2014

Heat-shock induces rapid resorption of primary cilia

por Thompson, CL, Prodromou, NV, Osborn, DP, Ashworth, R, Knight, MM, Beales, PL, Chapple, JP
Publicado 2012

IFT88 influences chondrocyte actin organization and biomechanics

por Wang, Z., Wann, A.K.T., Thompson, C.L., Hassen, A., Wang, W., Knight, M.M.
Publicado 2016

Activation of TRPV4 by mechanical, osmotic or pharmaceutical stimulation is anti-inflammatory blocking IL-1β mediated articular cartilage matrix destruction

por Fu, S., Meng, H., Inamdar, S., Das, B., Gupta, H., Wang, W., Thompson, C.L., Knight, M.M.
Publicado 2021

Mechanical loading inhibits cartilage inflammatory signalling via an HDAC6 and IFT-dependent mechanism regulating primary cilia elongation

por Fu, S., Thompson, C.L., Ali, A., Wang, W., Chapple, J.P., Mitchison, H.M., Beales, P.L., Wann, A.K.T., Knight, M.M.
Publicado 2019