Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade

por Cloherty, Alexandra P. M., Rader, Anusca G., Patel, Kharishma S., Pérez-Vargas, Jimena, Thompson, Connor A. H., Ennis, Siobhan, Niikura, Masahiro, Wildenberg, Manon E., Muncan, Vanesa, Schreurs, Renée R. C. E., Jean, François, Ribeiro, Carla M. S.
Publicado 2023

A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic

por Shapira, Tirosh, Monreal, I. Abrrey, Dion, Sébastien P., Buchholz, David W., Imbiakha, Brian, Olmstead, Andrea D., Jager, Mason, Désilets, Antoine, Gao, Guang, Martins, Mathias, Vandal, Thierry, Thompson, Connor A. H., Chin, Aaleigha, Rees, William D., Steiner, Theodore, Nabi, Ivan Robert, Marsault, Eric, Sahler, Julie, Diel, Diego G., Van de Walle, Gerlinde R., August, Avery, Whittaker, Gary R., Boudreault, Pierre-Luc, Leduc, Richard, Aguilar, Hector C., Jean, François
Publicado 2022

A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants

por Pérez-Vargas, Jimena, Worrall, Liam J., Olmstead, Andrea D., Ton, Anh-Tien, Lee, Jaeyong, Villanueva, Ivan, Thompson, Connor A. H., Dudek, Svenja, Ennis, Siobhan, Smith, Jason R., Shapira, Tirosh, De Guzman, Joshua, Gang, Shutong, Ban, Fuqiang, Vuckovic, Marija, Bielecki, Michael, Kovacic, Suzana, Kenward, Calem, Hong, Christopher Yee, Gordon, Danielle G., Levett, Paul N., Krajden, Mel, Leduc, Richard, Boudreault, Pierre-Luc, Niikura, Masahiro, Paetzel, Mark, Young, Robert N., Cherkasov, Artem, Strynadka, Natalie C. J., Jean, François
Publicado 2023

Corrigendum to “Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics” “Antiviral Research 209 (2023)/105484”

por Perez-Vargas, Jimena, Shapira, Tirosh, Olmstead, Andrea D., Villanueva, Ivan, Thompson, Connor A.H., Ennis, Siobhan, Gao, Guang, De Guzman, Joshua, Williams, David E., Wang, Meng, Chin, Aaleigha, Bautista-Sanchez, Diana, Agafitei, Olga, Levett, Paul, Xie, Xuping, Nuzzo, Genoveffa, Freire, Vitor F., Quintana-Bulla, Jairo I., Bernardi, Darlon I., Gubiani, Juliana R., Suthiphasilp, Virayu, Raksat, Achara, Meesakul, Pornphimol, Polbuppha, Isaraporn, Cheenpracha, Sarot, Jaidee, Wuttichai, Kanokmedhakul, Kwanjai, Yenjai, Chavi, Chaiyosang, Boonyanoot, Teles, Helder Lopes, Manzo, Emiliano, Fontana, Angelo, Leduc, Richard, Boudreault, Pierre-Luc, Berlinck, Roberto G.S., Laphookhieo, Surat, Kanokmedhakul, Somdej, Tietjen, Ian, Cherkasov, Artem, Krajden, Mel, Nabi, Ivan Robert, Niikura, Masahiro, Shi, Pei-Yong, Andersen, Raymond J., Jean, François
Publicado 2023

Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics

por Pérez-Vargas, Jimena, Shapira, Tirosh, Olmstead, Andrea D., Villanueva, Ivan, Thompson, Connor A.H., Ennis, Siobhan, Gao, Guang, De Guzman, Joshua, Williams, David E., Wang, Meng, Chin, Aaleigha, Bautista-Sánchez, Diana, Agafitei, Olga, Levett, Paul, Xie, Xuping, Nuzzo, Genoveffa, Freire, Vitor F., Quintana-Bulla, Jairo I., Bernardi, Darlon I., Gubiani, Juliana R., Suthiphasilp, Virayu, Raksat, Achara, Meesakul, Pornphimol, Polbuppha, Isaraporn, Cheenpracha, Sarot, Jaidee, Wuttichai, Kanokmedhakul, Kwanjai, Yenjai, Chavi, Chaiyosang, Boonyanoot, Teles, Helder Lopes, Manzo, Emiliano, Fontana, Angelo, Leduc, Richard, Boudreault, Pierre-Luc, Berlinck, Roberto G.S., Laphookhieo, Surat, Kanokmedhakul, Somdej, Tietjen, Ian, Cherkasov, Artem, Krajden, Mel, Nabi, Ivan Robert, Niikura, Masahiro, Shi, Pei-Yong, Andersen, Raymond J., Jean, François
Publicado 2023